職名 教授
氏名 さくまはじめ
佐久間 肇
生年月 1960.04
所属 部局 医学系研究科
学科・専攻 生命医科学専攻
講座 臨床医学系講座
教育研究分野 放射線医学
TEL 059-231-5029
FAX 059-232-8066
E-mail sakuma@clin.medic. (末尾に mie-u.ac.jp を補ってください)
個人のホームページ  
学歴 三重大学医学部 学士課程 (~1985年)
博士課程・博士後期課程 (~)
学位 1991.12 医学博士 三重大学
所属学会 日本医学放射線学会 日本核医学会 日本磁気共鳴医学会 Society for Cardiovascular Magnetic Resonance Radiological Society of North America International Society for Magnetic Resonance
社会活動  
職歴 1985.05~1987.03 三重大学医学部附属病院放射線科 医員研修医
1987.04~1988.03 三重大学医学部附属病院 放射線科 医員
1988.04~1988.06 福井医科大学附属病院放射線科 助手
1989.07~1991.10 三重大学医学部附属病院放射線科 助手
1991.11~1996.03 カリフォルニア大学サンフランシスコ校放射線科 Research fellow
1996.04~1996.10 三重大学医学部附属病院放射線科 助手
1996.11~1998.10 三重大学医学部附属病院放射線科 講師
1998.11~ 三重大学医学部附属病院中央放射線部 准教授
2009.04~ 三重大学医学部附属病院中央放射線部 部長
2009.07~ 三重大学医学部附属病院放射線診断科 科長
2012.06~ 三重大学大学院医学系研究科放射線医学教授
学術(芸術)賞  
専門分野 放射線科 画像診断学 Magnetic Resonance Imaging (MRI) 心臓大血管の画像診断
現在の研究課題 循環器画像診断 心臓冠動脈MRI、心臓CT、PET
担当科目 がんの画像診断 画像診断 今週の画像 循環器画像診断の進歩と役割
主な業績等 Prognostic Value of Stress Dynamic Computed Tomography Perfusion With Computed Tomography Delayed Enhancement. 2020.08 JACC. Cardiovascular imaging 13 1721-1734
Multimodality Imaging for More Accurate Diagnosis and Risk Assessment in Infective Endocarditis. 2020.11 Radiology 297 342-343
Myocardial Coverage and Radiation Dose in Dynamic Myocardial Perfusion Imaging Using Third-Generation Dual-Source CT. 2020.01 Korean journal of radiology 21 58-67
Monitoring of the Evolution of Immune Checkpoint Inhibitor Myocarditis With Cardiovascular Magnetic Resonance. 2020.11 Circulation. Cardiovascular imaging 13 e010633-
(18)F-FDG uptake as a predictive factor for progressive aortic enlargement in aortic dissection. 2020.09 Annals of nuclear medicine 34 636-642
Improving Image Resolution of Whole-Heart Coronary MRA Using Convolutional Neural Network. 2020.04 Journal of digital imaging 33 497-503
Myocardial Native T(1) Predicts Load-Independent Left Ventricular Chamber Stiffness In Patients With HFpEF. 2020.10 JACC. Cardiovascular imaging 13 2117-2128
Editorial for "Evaluation of Vascular Reactivity of Maternal Vascular Adaptations of Pregnancy With Quantitative MRI". 2020.09 Journal of magnetic resonance imaging : JMRI
Quantification of extracellular volume fraction by cardiac computed tomography for noninvasive assessment of myocardial fibrosis in hemodialysis patients. 2020.09 Scientific reports 10 15367-
Feasibility of extracellular volume fraction calculation using myocardial CT delayed enhancement with low contrast media administration. 2020.02 Journal of cardiovascular computed tomography
Early alteration in apparent diffusion coefficient and tumor volume in cervical cancer treated with chemoradiotherapy or radiotherapy: Incremental prognostic value over pretreatment assessments. 2020.10 Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 155 3-9
The value of Bayesian penalized likelihood reconstruction for improving lesion conspicuity of malignant lung tumors on (18)F-FDG PET/CT: comparison with ordered subset expectation maximization reconstruction incorporating time-of-flight model and point spread function correction. 2020.04 Annals of nuclear medicine 34 272-279
Perfusion CT to Assess Response to Neoadjuvant Chemotherapy and Radiation Therapy in Pancreatic Ductal Adenocarcinoma: Initial Experience. 2019.09 Radiology 292 628-635
Cardiovascular magnetic resonance feature tracking for characterization of patients with heart failure with preserved ejection fraction: correlation of global longitudinal strain with invasive diastolic functional indices. 2020.06 Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 22 42-
Coronary CT Angiography Fractional Flow Reserve Analysis: A Practical Tool or a Luxury for Research Centers? 2019.09 Radiology 292 606-607
Incremental Prognostic Value of Myocardial Blood Flow Quantified WithツStress Dynamic Computed Tomography Perfusion Imaging. 2019.07 JACC. Cardiovascular imaging 12 1379-1387
Comparison of the different imaging time points in delayed phase cardiac CT for myocardial scar assessment and extracellular volume fraction estimation in patients with old myocardial infarction. 2019.05 The international journal of cardiovascular imaging 35 917-926
Usefulness of dictionary learning-based processing for improving image quality of sub-millisievert low-dose chest CT: initial experience. 2020.03 Japanese journal of radiology 38 215-221
Assessment of coronary flow velocity reserve with phase-contrast cine magnetic resonance imaging in patients with heavy coronary calcification. 2019.05 The international journal of cardiovascular imaging 35 897-905
Native T1 Mapping and Extracellular Volume Mapping for the Assessment of Diffuse Myocardial Fibrosis in DilatedツCardiomyopathy. 2018.01 JACC. Cardiovascular imaging 11 48-59
2D Flow CMR for Risk Assessment inツCoronary Artery Disease: An Alternative to PET? 2019.08 JACC. Cardiovascular imaging 12 1696-1698
CT-based attenuation correction and resolution compensation for I-123 IMP brain SPECT normal database: a multicenter phantom study. 2018.06 Annals of nuclear medicine 32 311-318
Incremental Prognostic Value of Myocardial Blood Flow Quantified WithツStress Dynamic Computed Tomography Perfusion Imaging. 2019.07 JACC. Cardiovascular imaging 12 1379-1387
Effect of Sitagliptin on Coronary Flow Reserve Assessed by Magnetic Resonance Imaging in Type 2 Diabetic Patients With Coronary Artery Disease. 2018.07 Circulation journal : official journal of the Japanese Circulation Society 82 2119-2127
Prognostic impact of unrecognized myocardial scar in the non-culprit territories by cardiac magnetic resonance imaging in patients with acute myocardial infarction. 2018.01 European heart journal cardiovascular Imaging 19 108-116
Comparison of the different imaging time points in delayed phase cardiac CT for myocardial scar assessment and extracellular volume fraction estimation in patients with old myocardial infarction. 2019.05 The international journal of cardiovascular imaging 35 917-926
Myocardial Extracellular Volume Fraction and Change in Hematocrit Level: MR Evaluation by Using T1 Mapping in an Experimental Model of Anemia. 2018.07 Radiology 288 93-98
Combined Assessment of Stress Myocardial Perfusion Cardiovascular Magnetic Resonance and Flow Measurement in the Coronary Sinus Improves Prediction of Functionally Significant Coronary Stenosis Determined by Fractional Flow Reserve in Multivessel Disease. 2018.01 Journal of the American Heart Association 7
Myocardial tissue characterization and strain analysis in healthy pregnant women using cardiovascular magnetic resonance native T1 mapping and feature tracking technique. 2018.08 Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20 52-
Usefulness of abdominal belt for restricting respiratory cardiac motion and improving image quality in myocardial perfusion PET. 2018.04 Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 25 407-415
2017 Multimodality Appropriate Use Criteria for Noninvasive Cardiac Imaging: Expert Consensus of the Asian Society of Cardiovascular Imaging. 2017.11 Korean journal of radiology 18 871-880
Diagnostic Accuracy of Endocardial-to-Epicardial Myocardial Blood Flow Ratio for the Detection of Significant Coronary Artery Disease With Dynamic Myocardial Perfusion Dual-Source Computed Tomography. 2017.09 Circulation journal : official journal of the Japanese Circulation Society 81 1477-1483
Prognostic Value of Combined CT Angiography and Myocardial Perfusion Imaging versus Invasive Coronary Angiography and Nuclear Stress Perfusion Imaging in the Prediction of Major Adverse Cardiovascular Events: The CORE320 Multicenter Study. 2017.07 Radiology 284 55-65
Native Myocardial T1 Mapping, Are We There Yet? 2016.07 International heart journal 57 400-7
The impact of epidermal growth factor receptor mutations on patterns of disease recurrence after chemoradiotherapy for locally advanced non-small cell lung cancer: a literature review and pooled analysis. 2016.09 Journal of radiation research 57 449-459
Data on correlation between CT-derived and MRI-derived myocardial extracellular volume. 2016.06 Data in brief 7 1045-1047
The impact of emphysema on dosimetric parameters for stereotactic body radiotherapy of the lung. 2016.09 Journal of radiation research 57 555-566
The Effect of Misregistration Between CT-Attenuation and PET-Emission Images in 13N-Ammonia Myocardial PET/CT. 2016.06 Journal of nuclear medicine technology 44 73-7
Tracking isolated myocarditis in a young adult with acute rheumatic fever on cardiac magnetic resonance imaging. 2016.11 International journal of cardiology 222 921-923
Usefulness of abdominal belt for restricting respiratory cardiac motion and improving image quality in myocardial perfusion PET. 2018.04 Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 25 407-415
Persistent Left Ventricular Apical Ballooning Induced by Right Ventricular Apical Pacing. 2015 Circulation journal : official journal of the Japanese Circulation Society 79 2723-5
Radiofrequency Ablation Using a Multiple-Electrode Switching System for Lung Tumors with 2.0-5.0-cm Maximum Diameter: Phase II Clinical Study. 2015.12 Radiology 277 895-902
Theoretical considerations in measurement of time discrepancies between input and myocardial time-signal intensity curves in estimates of regional myocardial perfusion with first-pass contrast-enhanced MRI. 2015.11 Magnetic resonance imaging 33 1059-1065
Coronary CT versus MR angiography: the role of MR angiography. 単著 2011.02 Radiology 258 340-349
Assessment of coronary artery disease using magnetic resonance coronary angiography: a national multicenter trial. 共著 2010.09 Journal of the American College of Cardiology 56 983-91
Hypertension impairs myocardial blood perfusion reserve in subjects without regional myocardial ischemia. 共著 2010.11 Hypertension Research 33 1144-9
Single-breath-hold multiple-slice DENSE MRI. 共著 2010.05 Magnetic Resonance in Medicine 63 1411-4
Vegetation with ventricular septal defect detected by cardiac magnetic resonance imaging. 共著 2010.03 Circulation Journal 74 592-593
Relation between signal intensity on T2-weighted MR images and presence of microvascular obstruction in patients with acute myocardial infarction. 2009.10 AJR. American journal of roentgenology 193 0-6
Cardiac MRI in ischemic heart disease. 共著 2009.09 Circulation Journal 73 1577-88
Quantitative analysis of first-pass contrast-enhanced myocardial perfusion MRI using a Patlak plot method and blood saturation correction. 2009.08 Magnetic Resonance in Medicine 62 373-383
Diagnostic accuracy of 1.5-T unenhanced whole-heart coronary MR angiography performed with 32-channel cardiac coils: initial single-center experience. 共著 2011.05 Radiology 259 384-92
Quantification of myocardial blood flow using model based analysis of first-pass perfusion MRI: Extraction fraction of Gd-DTPA varies with myocardial blood flow in human myocardium. 共著 2011.04 Magnetic Resonance in Medicine 0-0
Influence of T1-recovery and off-resonance effects in DENSE MRI. 共著 2011.04 Magnetic Resonance in Medicine 0-0
Unique myocardial fibrosis pattern by late gadolinium enhanced magnetic resonance imaging in a patient with isolated noncompaction of the ventricular myocardium. 共著 2010.02 Circulation Journal 74 381-382
Regional myocardial perfusion reserve determined using myocardial perfusion magnetic resonance imaging showed a direct correlation with coronary flow velocity reserve by Doppler flow wire 共著 2009.02 European Heart Journal 30 444-452
Absolute blood contrast concentration and blood signal saturation on myocardial perfusion MRI: estimation from CT data. 共著 2009.01 Journal of Magnetic Resonance Imaging 29 205-210
Prediction of regional functional recovery after acute myocardial infarction with low dose dobutamine stress cine MR imaging and contrast enhanced MR imaging. 共著 2003.11 Clinical Nucler Medicine 28 890-892
Prognostic value of coronary magnetic resonance angiography for prediction of cardiac events in patients with suspected coronary artery disease. 共著 2012.12 Journal of the American College of Cardiology 60 2316-22
Impaired myocardial perfusion reserve in patients with fatty liver disease assessed by quantitative myocardial perfusion magnetic resonance imaging. 共著 2012.06 Circulation journal : official journal of the Japanese Circulation Society 76 2234-40
Prognostic significance of unrecognized myocardial infarction detected with MR imaging in patients with impaired fasting glucose compared with those with diabetes. 共著 2012.03 Radiology 262 807-15
Arrhythmogenic Right Ventricular Cardiomyopathy in a 20-year-old Woman with Systemic Sclerosis. 共著 2014 Internal medicine (Tokyo, Japan) 53 973-7
Magnetic resonance of coronary arteries: assessment of luminal narrowing and blood flow in the coronary arteries. 共著 2014.05 Journal of thoracic imaging 29 155-62
Late gadolinium enhancement and prognosis of hypertrophic cardiomyopathy. 単著 2014.03 Circulation journal 78 832-4
Radiofrequency ablation for ground-glass opacity-dominant lung adenocarcinoma. 共著 2014.03 Journal of vascular and interventional radiology 25 333-9
Altered coronary endothelial function in young smokers detected by magnetic resonance assessment of myocardial blood flow during the cold pressor test. 共著 2014.06 The international journal of cardiovascular imaging 30 Suppl 1 73-80
Detection of diminished response to cold pressor test in smokers: assessment using phase-contrast cine magnetic resonance imaging of the coronary sinus. 共著 2014.04 Magnetic resonance imaging 32 217-23
Quantitative analysis of 1.5-T whole-heart coronary MR angiograms obtained with 32-channel cardiac coils: a comparison with conventional quantitative coronary angiography. 共著 2014.05 Radiology 271 356-64
Radiofrequency ablation for the treatment of recurrent bone and soft-tissue sarcomas in non-surgical candidates. 共著 2013.11 International journal of clinical oncology
Dose reduction in dynamic CT stress myocardial perfusion imaging: comparison of 80-kV/370-mAs and 100-kV/300-mAs protocols. 共著 2014.03 European radiology 24 748-55
Radiofrequency Ablation After Arterial Injection of Miriplatin-Iodized Oil Suspension Into Swine Liver: Ablative Zone Size and Tissue Platinum Concentration. 共著 2013.11 Cardiovascular and interventional radiology
Stent placement for treating IVC stenosis following "left at right" adult liver transplantation. 共著 2013.09 American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Tr 13 2775-6
Model-based iterative reconstruction for multi-detector row CT assessment of the Adamkiewicz artery. 共著 2014.01 Radiology 270 282-91
Quantitative assessment of myocardial strain with displacement encoding with stimulated echoes MRI in patients with coronary artery disease. 共著 2013.12 international journal of cardiovascular imaging 29 1779-86
CT of the chest with model-based, fully iterative reconstruction: comparison with adaptive statistical iterative reconstruction. 共著 2013.08 BMC medical imaging 13 27-
Radiofrequency ablation versus radical nephrectomy: clinical outcomes for stage T1b renal cell carcinoma. 共著 2013.10 Radiology 270 292-9
Myocardial perfusion reserve is impaired in patients with chronic obstructive pulmonary disease: a comparison to current smokers. 共著 2014.02 European heart journal cardiovascular Imaging 15 180-8
Prognostic value of unrecognised myocardial infarction detected by late gadolinium-enhanced MRI in diabetic patients with normal global and regional left ventricular systolic function. 共著 2013.08 European radiology 23 2101-8
Experimental assessment of temperature influence on miriplatin and cisplatin iodized-oil suspension viscosity. 共著 2013.06 Japanese journal of radiology 31 424-7
Survival with up to 10-year follow-up after combination therapy of chemoembolization and radiofrequency ablation for the treatment of hepatocellular carcinoma: single-center experience. 共著 2013.05 Journal of vascular and interventional radiology : JVIR 24 655-66
Prediction of regional functional recovery after acute myocardial infarction with low dose dobutamine stress cine MR imaging and contrast enhanced MR imaging. 共著 2003 Journal of Cardiovascular Magnetic Resonance 5 563-74
Evaluation of left ventricular volumes and ejection fraction using fast steady-state cine MR imaging: comparison with left ventricular angiography. 共著 2003.05 Journal of Cardiovascular Magnetic Resonance 5 333-42
Acute myocardial infarction: myocardial viability assessment in patients early thereafter comparison of contrast-enhanced MR imaging with resting (201)Tl SPECT. Single photon emission computed tomography. 共著 2003.01 Radiology 226 138-44
Noninfarcted myocardium: correlation between dynamic first-pass contrast-enhanced myocardial MR imaging and quantitative coronary angiography. 共著 2003.10 Radiology 229 209-16
Thallium-201 SPECT and low-dose dobutamine stress cine MRI for predicting functional recovery of regional myocardial contraction in patients with myocardial infarction. 共著 2004.09 Journal of Cardiovascular Magnetic Resonance 6 697-707
Late gadolinium-enhanced magnetic resonance imaging in acute and chronic myocardial infarction. Improved prediction of regional myocardial contraction in the chronic state by measuring thickness of nonenhanced myocardium. 共著 2005.03 Journal of the American College of Cardiology 45 901-9
Diagnostic accuracy of stress first-pass contrast-enhanced myocardial perfusion MRI compared with stress myocardial perfusion scintigraphy. 共著 2005.07 AJR. American Journal of roentgenology 185 95-102
Feasibility of integrating high-spatial-resolution 3D breath-hold coronary MR angiography with myocardial perfusion and viability examinations 共著 2005.06 Radiology 235 1025-1030
Comparison of MRI and positron emission tomography for measuring myocardial perfusion reserve in healthy humans. 共著 2006.04 Magnetic Resonance in Medicine 55 772-9
Apparent diffusion coefficient in malignant lymphoma and carcinoma involving cavernous sinus evaluated by line scan diffusion-weighted imaging. 共著 2006.09 Journal of Magnetic Resonance Imaging 24 543-8
Detection of coronary artery stenosis with whole-heart coronary magnetic resonance angiography. 共著 2006.11 Journal of the American College of Cardiology 48 1946-50
Magnetic resonance imaging for ischemic heart disease. 単著 2007.07 Journal of magnetic resonance imaging : JMRI 26 3-13
Diagnostic value of late gadolinium-enhanced MRI and first-pass dynamic MRI for predicting functional recovery in patients after acute myocardial infarction. 共著 2007.07 Radiation Medicine 25 263-71
Two cases of dilated cardiomyopathy with right ventricular wall degeneration demonstrated by late gadolinium enhanced MRI. 共著 2007.08 International journal of cardiology 0-0
Apparent diffusion coefficient of pituitary macroadenoma evaluated with line-scan diffusion-weighted imaging. 共著 2007.10 Journal of Neuroradiology 34 228-35
A case of clover-shaped left ventricular non-compaction. 共著 2008.02 European heart journal 29 569-0
Correlation between late gadolinium enhancement and diastolic function in hypertrophic cardiomyopathy assessed by magnetic resonance imaging. 共著 2008.03 Circulation Journal 72 378-83
Two cases of dilated cardiomyopathy with right ventricular wall degeneration demonstrated by late gadolinium enhanced MRI. 共著 2008.09 International Journal of Cardiology 129 0-3
Diagnostic accuracy of stress myocardial perfusion MRI and late gadolinium-enhanced MRI for detecting flow-limiting coronary artery disease: a multicenter study. 共著 2008.12 European radiology 18 2808-16
Regional myocardial perfusion reserve determined using myocardial perfusion magnetic resonance imaging showed a direct correlation with coronary flow velocity reserve by Doppler flow wire. 共著 2009.02 European heart journal 30 444-52
Quantitative assessment of regional systolic and diastolic functions and temporal heterogeneity of myocardial contraction in patients with myocardial infarction using cine magnetic resonance imaging and Fourier fitting. 共著 2009.07 Magnetic Resonance Imaging 0-0
Adipose tissue detected by multislice computed tomography in patients after myocardial infarction. 共著 2009.05 Journal of American College of Cardiology - Cardiovascular Imaging 2 548-555
Quantitative analysis of first-pass contrast-enhanced myocardial perfusion MRI using a Patlak plot method and blood saturation correction. 共著 2009.08 Magnetic Resonance in Medicine 62 373-83
Cardiac MRI in Ischemic Heart Disease 共著 2009.09 Circulation Journal 73 1577-1588