職名 准教授
氏名 はせがわまさひろ
長谷川 正裕
生年月 1965.06
所属 部局 医学系研究科
学科・専攻 生命医科学専攻
講座 臨床医学系講座
教育研究分野 整形外科
TEL 059-231-5022
FAX 059-231-5211
E-mail masahase@clin.medic. (末尾に mie-u.ac.jp を補ってください)
個人のホームページ  
学歴 三重大学医学部 学士課程 (~1990年)
三重大学医学部大学院 博士課程・博士後期課程 (~1999年)
学位 1999.12 医学博士 三重大学
所属学会 Orthopaedic Research Society 日本整形外科学会 日本リウマチ学会 日本人工関節学会 中部日本整形外科災害外科学会 日本股関節学会 日本関節病学会 日本リハビリテーション医学会 日本関節鏡・膝・スポーツ整形外科学会 中部リウマチ学会 日本結合組織学会
社会活動  
職歴 1990~1991 三重大学医学部附属病院整形外科
1991~1994 松阪市民病院整形外科
1998~2000 朝日大学村上記念病院整形外科 助手
2000~2001 朝日大学村上記念病院整形外科 講師
2001~2002 三重大学医学部附属病院整形外科  医員
2002~2007 三重大学医学部附属病院整形外科  講師
2017~ 三重大学医学部附属病院整形外科 准教授
学術(芸術)賞 中冨健康科学振興財団 研究助成賞,変形性膝関節症におけるマトリックス細胞タンパクの機能,2008,中冨健康科学振興財団
吉田壽記念三重医学研究振興会賞,人工関節置換術,2018,三重医学研究振興会
第14回日本CAOS研究会・第26回日本最小侵襲整形外科学会 web奨励賞,AR技術を用いたCT-based ナビゲーションの開発,2020,第14回日本CAOS研究会・第26回日本最小侵襲整形外科学会
専門分野 股関節外科、膝関節外科、人工関節、人工材料
現在の研究課題 関節マーカー 人工関節 軟骨修復
担当科目 整形外科
主な業績等 Thrombin-cleaved osteopontin in synovial fluid of subjects with rheumatoid arthritis 共著 2009 J Rheumatol 36 240-245
Staged bilateral mobile-bearing and fixed-bearing total knee arthroplasty in the same patients: a prospective comparison of a posterior-stabilized prosthesis 共著 2009 Knee Surg Sports Traumatol Arthrosc 17 237-243
Subchondral insufficiency fracture of the second metatatarsal head in an eldery woman treated with autologous osteochondral transplantation 共著 2009 Arch Orthop Trauma Surg 128 689-693
Total knee arthroplasty in osteogenesis imperfecta: Case report 共著 2008 Knee 15 494-496
An infant with unexplained multiple rib fractures occurring during treatment in a neonatal intensive care unit 共著 2008 Turk J Pediatr 50 377-379
Unilateral stress fracture of the femoral shaft combined with contralateral insuffi ciency fracture of the femoral shaft after bilateral total knee arthroplasty 共著 2008 J Orthop Sci 13 572-575
Course of avascular necrosis of femoral head without collapse of femoral head at first examination: minimum 8-year follow-up: 共著 2008 Orthopedics 31 755-
Long-term results of bipolar hemiarthroplasty for osteoarthritis of the hip and idiopathic osteonecrosis of the femoral head: 共著 2008 J Orthop Sci 13 313-317
A long-term follow-up study of the cementless THA with anatomic stem/HGPII cup with 22-mm head.: 共著 2009 Int Orthop 33 381-385
Cut-off values of D-dimer and soluble fibrin for prediction of deep vein thrombosis after orthopaedic surgery: 共著 2009 Int J Hematol 89 572-576
Changes to patellar blood flow after minimally invasive total knee arthroplasty: 共著 2009 Knee Surg Sports Traumatol Arthrosc 17 1195-1198
Devastating ochronotic arthropathy with successful bilateral hip and knee arthroplasties: 共著 2009 J Clin Rheumatol 15 138-140
Late small intestine perforation after cementless total hip arthroplasty: 共著 2009 Hip International 19 399-401
Deficiency of tenascin-C delays articular cartilage repair in mice: 共著 2010 Osteoarthritis Cartilage 18 839-848
Evaluation of soluble fibrin and D-dimer in the diagnosis of postoperative deep vein thrombosis: 共著 2010 Biomarkers 15 149-157
Serum metal ion levels after second-generation metal-on-metal total hip arthroplasty: 共著 2010 Arch Orthop Trauma Surg 130 1447-11450
Retrospective clinical study of the efficacy of lower-dose methotrexate and infliximab therapy in patients with rheumatoid arthritis: 共著 2010 Clin Rheumatol
Incidence and time course of asymptomatic deep vein thrombosis with fondaparinux in patients undergoing total joint arthroplasty: 共著 2010 Thromb Res 126 323-326
The cleavage of N-cadherin is essential for chondrocyte differentiation: 共著 2010 Biochem Biophys Res Commun
Distribution and role of tenascin-C in human osteoarthritic cartilage: 共著 2010 J Orthop Sci 15 666-673
Minimally invasive total knee arthroplasty: comparison of jig-based technique versus computer navigation for clinical and alignment outcome: 共著 2011 Knee Surg Sports Traumatol Arthrosc 19 904-910
Thrombin-cleaved osteopontin levels in synovial fluid correlate with disease severity of knee osteoarthritis: 共著 2011 J Rheumatol 38 129-134
Do biologics-naïve patients with rheumatoid arthritis respond better to tocilizumab than patients for whom anti-TNF agents have failed? A retrospective study: 共著 2011 Clin Exp Rheumatol
Risk factors for the incidence and progression of radiographic osteoarthritis of the knee among Japanese: 共著 2011 Int Orthop
Monitoring for anti-Xa activity for prophylactic administration of Fondaparinux in patients with artificial joint replacement: 共著 2011 Int J Hematol
Recurrent hemarthrosis after unicompartmental knee arthroplasty.: 共著 2011 Orthopedics
The influence of fondaparinux on the diagnosis of postoperative deep vein thrombosis by soluble fibrin and D-dimer: 共著 2012 Thromb Res 130 759-764
Which subgroup of rheumatoid arthritis patients benefits from switching to tocilizumab versus etanercept after previous infliximab failure? A retrospective study: 共著 2012 Mod Rheumatol 22 116-121
Risk factor for a residual deep vein thrombosis after fondaparinux administration in patient with postoperative replacement arthroplasty 共著 2012 Yakugaku Zasshi 132 683-687
Increased fibrinolysis increases bleeding in orthopedic patients receiving prophylactic fondaparinux: 共著 2012 Int J Hematol 95 160-166
Cobalt and chromium ion release after large-diameter metal-on-metal total hip arthroplasty: 共著 2012 J Arthroplasty 27 990-996
Prevalence and characteristics of unilateral knee osteoarthritis in a community sample of elderly Japanese: do fractures around the knee affect the pathogenesis of unilateral knee osteoarthritis?: 共著 2012 J Orthop Sci 17 556-561
Transfection of nuclear factor kappa B decoy oligodeoxynucleotide protects against ischemia/reperfusion injury in rat epigastric flap model: 共著 2012 J Gene Med 14 623-631
Repeat etanercept administration restores clinical response of patients with rheumatoid arthritis: 共著 2012 Rheumatol Int 32 3675-3678
Day zero ambulation under modified femoral nerve block after minimally invasive surgery for total knee arthroplasty: preliminary report: 共著 2013 J Anesth 27 132-134
Pseudotumor With Dominant B-Lymphocyte Infiltration After Metal-On-Metal Total Hip Arthroplasty With a Modular Cup.: 共著 2012 J Arthroplasty 27 493.e5-493.e7
Recurrent knee valgus deformity in Ellis-van Creveld syndrome.: 共著 2012 J Pediatr Orthop B 21 352-355-352-355
Failure mechanism of a constrained liner: a case report.: 共著 2012 Acta Orthop Belg 78 129-133
A tumor endoprosthesis is useful in elderly rheumatoid arthritis patient with acute intercondylar fracture of the distal femur.: 共著 2012 Rheumatol Int 32 1411-1413
Cutting and implanting errors in minimally invasive total knee arthroplasty using a navigation system: 共著 2013 Int Orthop 37 27-30
Clinical outcome in patients with rheumatoid arthritis switched to tocilizumab after etanercept or infliximab failure: 共著 2013 Clin Rheumatol 32 253-259
"Protective effect of edaravone for tourniquet-induced ischemia-reperfusion injury on skeletal muscle in murine hindlimb.::": 共著 2013 BMC Musculoskelet Disord 14 113-
In vivo wear performance of highly cross-linked polyethylene vs. yttria stabilized zirconia and alumina stabilized zirconia at a mean seven-year follow-up.: 共著 2013 BMC Musculoskelet Disord 14 154-
Prevalence of Adverse Reactions to Metal Debris associated with Large-Diameter Metal-on-Metal Total Hip Arthroplasty: 共著 2013 Orthopedics 36 e606-e612-e606-e612
Hip score and disease activity correlation in patients with rheumatoid arthritis after total hip arthroplasty.: 共著 2013 Int Orthop 37 1245-1250
Deep-vein thrombosis after resection of musculoskeletal tumours of the lower limb.: 共著 2013 Bone Joint J 95-B 1280-1284
The efficacy of rebamipide add-on therapy in arthritic patients with COX-2 selective inhibitor-related gastrointestinal events: a prospective, randomized, open-label blinded-endpoint pilot study by the GLORIA study group: 共著 2013 Mod Rheumatol 23 1172-1178
The relationships among hemostatic markers, the withdrawal of fondaparinux due to a reduction in hemoglobin and deep vein thrombosis in Japanese patients undergoing major orthopedic surgery.: 共著 2013 Clin Chim Acta 425 109-113-109-113
Comparison of midterm outcomes of minimally invasive computer-assisted vs minimally invasive jig-based total knee arthroplasty: 共著 2017.01 J Arthroplasty 32 43-46
Monitoring of hemostatic abnormalities in major orthopedic surgery patients treated with edoxaban by APTT waveform: 共著 2018.02 Int J Lab Hematol. 40 49-55
Role of tenascin-C in articular cartilage.: 共著 2018.03 Mod Rheumatol. 28 215-220
The Evaluation of Fibrin-Related Markers for Diagnosing or Predicting Acute or Subclinical Venous Thromboembolism in Patients Undergoing Major Orthopedic Surgery.: 共著 2018.01 Clin Appl Thromb Hemost 24 107-114
The Evaluation of D-Dimer Levels for the Comparison of Fibrinogen and Fibrin Units Using Different D-Dimer Kits to Diagnose VTE.: 共著 2018.05 Clin Appl Thromb Hemost 24 655-662
Factors Contributing to Patient Satisfaction and Expectations following Computer-Assisted Total Knee Arthroplasty.: 共著 2018.05 J Knee Surg 31 448-452
Prevalence of Persistent Pain after Total Knee Arthroplasty and the Impact of Neuropathic Pain.: 共著 2019 J Knee Surg
A case of bone necrosis with pseudotumor following metal-on-metal total hip arthroplasty : 共著 2017.10 Arthroplast Today 4 291-294
Factors associated with symptomatic pseudotumors following metal-on-metal total hip arthroplasty: 共著 BMC Musculoskelet Disord 17 456-
Immune response in adverse reactions to metal debris following metal-on-metal total hip arthroplasty.: 共著 BMC Musculoskelet Disord 17 221-
Prediction of post-operative range of motion using intra-operative soft tissue balance in total knee arthroplasty with navigation.: 共著 Comput Aided Surg 20 47-51
Longitudinal magnetic resonance imaging of pseudotumors following metal-on-metal total hip arthroplasty.: 共著 J Arthroplasty 29 2236-2238
Tenascin-C in Osteoarthritis and Rheumatoid Arthritis. 共著 2020.09 Front Immunol. 11 577015-
Alumina ceramic-on-ceramic total hip replacement with a layered acetabular component 共著 2006.07 J Bone Joint Surg (Br) 88 877-882
Cobalt-chromium head wear following revision hip arthroplasty performed after ceramic fracture-a case report 共著 2006 Acta Orthopaedica 77 833-835
Dislocation of posterior-stabilized mobile-bearing knee prosthesis A case report 共著 2006 Knee 13 478-482
Osteonecrosis of the femoral head caused by bone marrow blockage: a case report 共著 2006 J Orthop Surg (Hong Kong) 14 330-332
Computed tomographic evaluation of component position on dislocation after total hip arthroplasty 共著 2006 Orthopedics 29 1104-1108
Local delivery of antibiotics using hydroxyapatite with bi-modal pore size distribution 共著 2006 Key Engineering Materials 309-311 949-952
Mid-term results of ceramic-on-ceramic total hip arthroplasty with sandwich cup 共著 2006 Key Engineering Materials 309-311 1357-1362
Delayed multiple rupture of extensor tendons associated with a volarly displaced type II physeal fracture of radius 共著 2006 J Trauma 61 1549-1551
Ultrastructural characterization of tissue response to sintered carbonate apatite in rabbit bone 共著 2006 Dent Mater J 25 487-492
Expression of large tenascin-C splice variants in synovial fluid of patients with rheumatoid arthritis 共著 2007 J Orthop Res 25 563-568
A large metallic cyst caused by wear particles after total knee arthroplasty 共著 2007 Arch Orthop Trauma Surg 127 51-54
Large-scale gene expression profiles, differentially represented in osteoarthritic synovium of the knee joint using cDNA microarray technology 共著 2007 Biomarkers 12 384-402
Effect of tourniquet application on deep vein thrombosis after total knee arthroplasty 共著 2007 Arch Orthop Trauma Surg 127 671-675
Acetabular reconstruction using a cementless cup and hydroxyapatite granules: 3- to 8-year clinical results 共著 2007 J Arthroplasty 22 828-832
Regulation of Tenascin-C Expression by Tumor Necrosis Factor-alpha in Cultured Human Osteoarthritis Chondrocytes 共著 2008 J Rheumatol 35 147-152
Treatment of infected hip arthroplasty with antibiotic-impregnated calcium hydroxyapatite 共著 2008 J Arthroplasty 23 145-150
Changes in biochemical markers and prediction of effectiveness of intra-articular hyaluronan in patients with knee osteoarthritis 共著 2008 Osteoarthritis Cartilage 16 526-529
Bilateral Subchondral Insufficiency Fracture of the Femoral Head 共著 2008 Orthopedics 31 399-399
人工膝関節置換術[TKA]のすべて 共著 2007 メジカルビュー
カラー写真でみる!骨折・脱臼・捻挫 改訂版 共著 2010
カラー写真でみる!骨折・脱臼・捻挫 改訂版 共著 2010 羊土社
パーフェクト人工膝関節置換術 共著 2016 金芳堂
歯科アレルギーNOW 共著 2016 デンタルダイヤモンド社
Must & Never 大腿骨頚部・転子部骨折の治療と管理 共著 2017
Must & Never 大腿骨頚部・転子部骨折の治療と管理 共著 2017 南江堂