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三重大学教員紹介

教員情報

職名
教授
氏名
よしだとしみち
吉田 利通
生年月
1955.02
所属
部局
医学系研究科
学科・専攻
生命医科学専攻
講座
基礎医学系講座
教育研究分野
修復再生病理分野/病理学
TEL
059-232-1111(内線6356)
FAX
059-231-5009
E-mail
t-yosida@doc.medic. (末尾に mie-u.ac.jp を補ってください)
個人のホームページ
 
学歴
三重大学大学院医学系研究科 学士課程 (~1979年)
三重大学大学院医学研究科 博士課程・博士後期課程 (~1983年) 卒業・修了
学位
1983.07 医学博士 三重大学
所属学会
日本病理学会
日本細胞生物学会
日本癌学会
日本結合組織学会
American Society for Cell Biology
社会活動
 
職歴
1983.04~1991.05 三重大学医学部 助手
1991.06~1996.05 三重大学医学部 講師
1996.06~1999.07 三重大学医学部 助教授
学術(芸術)賞
 
専門分野
人体病理学 実験病理学 細胞生物学
現在の研究課題
細胞外マトリックスと組織修復・再生
担当科目
医学概論 修復再生病理学Ⅰ 修復再生病理学Ⅲ 病理・病態学 病理学 病理学各論
主な業績等
MMP-2 expression is associated with rapidly proliferative arteriosclerosis in the flexor tenosynovium and pain severity in carpal tunnel syndrome. 共著 2005.03 The Journal of pathology 205 4 443-50
Diagnostic utility of tenascin-C for evaluation of the activity of human acute myocarditis. 共著 2005.03 The Journal of pathology 205 4 460-7
Tenascin-C is an essential factor for neointimal hyperplasia after aortotomy in mice. 共著 2005.02 Cardiovascular research 65 3 737-42
Interleukin-1 receptor antagonist inhibits the expression of vascular endothelial growth factor in colorectal carcinoma. 共著 2005 Oncology 68 2-3 138-45
Increased expression of matrix metalloproteinase-2 in nasal polyps. 共著 2004.12 Acta oto-laryngologica 124 10 1165-70
Co-stimulation of human breast cancer cells with transforming growth factor-beta and tenascin-C enhances matrix metalloproteinase-9 expression and cancer cell invasion. 共著 2004.12 International journal of experimental pathology 85 6 373-9
Tenascin-C concentration in synovial fluid correlates with radiographic progression of knee osteoarthritis. 共著 2004.10 The Journal of rheumatology 31 10 2021-6
Locally applied cilostazol suppresses neointimal hyperplasia by inhibiting tenascin-C synthesis and smooth muscle cell proliferation in free artery grafts. 共著 2004.09 The Journal of thoracic and cardiovascular surgery 128 3 357-63
Interaction between cell and extracellular matrix in heart disease: multiple roles of tenascin-C in tissue remodeling. 共著 2004.04 Histology and histopathology 19 2 517-25
Targeted deletion of BMK1/ERK5 in adult mice perturbs vascular integrity and leads to endothelial failure. 共著 2004.04 The Journal of clinical investigation 113 8 1138-48
Rho kinases regulate endothelial invasion and migration during valvuloseptal endocardial cushion tissue formation. 共著 2006.01 Developmental dynamics : an official publication of the American Association of Anatomists 235 1 94-104
A crucial role of mitochondrial Hsp40 in preventing dilated cardiomyopathy. 共著 2006.01 Nature medicine 12 1 128-32
Tenascin-C levels in pseudosynovial fluid of loose hip prostheses. 共著 2005.11 Scandinavian journal of rheumatology 34 6 464-8
Tenascin-C-coated platinum coils for acceleration of organization of cavities and reduction of lumen size in a rat aneurysm model. 共著 2005.10 Journal of neurosurgery 103 4 681-6
Method of cell transplantation promoting the organization of intraarterial thrombus. 共著 2005.08 Circulation 112 9 Suppl 0-6
Expression of matrix metalloproteinase-3 in mouse endometrial stromal cells during early pregnancy: regulation by interleukin-1alpha and tenascin-C. 共著 2005.08 Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 21 2 111-8
Tenascin-C regulates recruitment of myofibroblasts during tissue repair after myocardial injury. 共著 2005.07 The American journal of pathology 167 1 71-80
Higher serum tenascin-C levels reflect the severity of heart failure, left ventricular dysfunction and remodeling in patients with dilated cardiomyopathy. 共著 2007.03 Circulation journal : official journal of the Japanese Circulation Society 71 3 327-30
Expression of large tenascin-C splice variants in synovial fluid of patients with rheumatoid arthritis. 共著 2007.01 J Orthop Res 0-0
Conditional N-rasG12V expression promotes manifestations of neurofibromatosis in a mouse model. 共著 2007.07 Oncogene 26 4714-9 0-0
Deficiency of tenascin-C attenuates liver fibrosis in immune-mediated chronic hepatitis in mice. 共著 2007.01 The Journal of pathology 211 1 86-94
Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice. 共著 2006.12 Oncogene 25 59 7673-9
Deficiency of tenascin C attenuates allergen-induced bronchial asthma in the mouse. 共著 2006.12 European journal of immunology 36 12 3334-45
Development of a new method for endovascular aortic repair: combination therapy of cell transplantation and stent grafts with a drug delivery system. 共著 2006.07 Circulation 114 1 Suppl 0-83
In vitro model for mouse coronary vasculogenesis. 共著 2006.07 The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 288 7 714-22
Serum tenascin-C might be a novel predictor of left ventricular remodeling and prognosis after acute myocardial infarction. 共著 2006.06 Journal of the American College of Cardiology 47 11 2319-25
Involvement of tenascin-C and PG-M/versican in flexor tenosynovial pathology of idiopathic carpal tunnel syndrome. 共著 2006.05 Histology and histopathology 21 5 511-8
Circulating level of large splice variants of tenascin-C is a marker of piecemeal necrosis activity in patients with chronic hepatitis C. 共著 2006.04 Liver international : official journal of the International Association for the Study of the Liver 26 3 311-8
Regenerating axons emerge far proximal to the coaptation site in end-to-side nerve coaptation without a perineurial window using a T-shaped chamber. 共著 2006.04 Plastic and reconstructive surgery 117 4 1194-203
脳血管攣縮とテネイシンC:Preliminary Study 共著 2005.03 脳血管攣縮 20 75-79 0-0
【関節炎マーカーの基礎と臨床】 関節液マーカーとなるテネイシンC 共著 2006.06 リウマチ科 35 565-570 0-0
Regulation of tenascin-C expression by tumor necrosis factor-alpha in cultured human osteoarthritis chondrocytes. 共著 2008.01 The Journal of rheumatology 35 1 147-52
Locally applied cilostazol suppresses neointimal hyperplasia and medial thickening in a vein graft model. 共著 2007.10 Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of A 13 5 322-30
Changes in biochemical markers and prediction of effectiveness of intra-articular hyaluronan in patients with knee osteoarthritis. 共著 2008.04 Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 16 4 526-9
Th1-type immune responses by Toll-like receptor 4 signaling are required for the development of myocarditis in mice with BCG-induced myocarditis. 共著 2007.09 Journal of autoimmunity 29 2-3 146-53
Eplerenone attenuates myocardial fibrosis in the angiotensin II-induced hypertensive mouse: involvement of tenascin-C induced by aldosterone-mediated inflammation. 共著 2007.05 Journal of cardiovascular pharmacology 49 5 261-8
Tenascin-C synthesized in both donor grafts and recipients accelerates artery graft stenosis. 2007.06 Cardiovascular research 74 3 366-76
Expression of large tenascin-C splice variants in synovial fluid of patients with rheumatoid arthritis. 2007.05 Journal of orthopaedic research : official publication of the Orthopaedic Research Society 25 5 563-8
Expression of large tenascin-C splice variants by hepatic stellate cells/myofibroblasts in chronic hepatitis C. 共著 2007.04 Journal of hepatology 46 4 664-73
Deficiency of tenascin-C delays articular cartilage repair in mice. 共著 2009.09 Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 0-0
Tenascin-C is induced in cerebral vasospasm after subarachnoid hemorrhage in rats and humans: a pilot study. 共著 2009.07 Neurological research 0-0
High prevalence of chronic myocarditis in dilated cardiomyopathy referred for left ventriculoplasty: expression of tenascin C as a possible marker for inflammation. 共著 2009.07 Human pathology 40 7 1015-22
Role of stromal tenascin-C in mouse prostatic development and epithelial cell differentiation. 2008.12 Developmental biology 324 2 310-9
Noninvasive detection of cardiac repair after acute myocardial infarction in rats by 111 In Fab fragment of monoclonal antibody specific for tenascin-C. 共著 2008.07 International heart journal 49 4 481-92
Cerebrospinal fluid tenascin-C increases preceding the development of chronic shunt-dependent hydrocephalus after subarachnoid hemorrhage. 共著 2008.05 Stroke; a journal of cerebral circulation 39 5 1610-2


更新日 2012-09-06
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