| 教員紹介トップページへ | 三重大学トップページへ |
| 職名 | 准教授 | |||||||||
| 氏名 | おいかわしんじ 及川 伸二 |
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| 生年月 | 1961.07 | |||||||||
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| s-oikawa@doc.medic. (末尾に mie-u.ac.jp を補ってください) | ||||||||||
| 個人のホームページ | http://www.medic.mie-u.ac.jp/eiseigaku/ | |||||||||
| 学歴 | 北海道大学水産学部 学士課程 (～1985年)
北海道大学大学院環境科学研究科 博士課程・博士後期課程 (～1993年) 卒業・修了 |
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| 学位 | 1993.03 博士（環境科学）
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| 所属学会 | 日本衛生学会、日本癌学会、日本分子生物学会、日本基礎老化学会、日本産業衛生学会、日本ヒトプロテオーム学会、日本光医学・光生物学会、日本環境変異原学会、日本生化学会、日本NO学会、日本フリーラジカル学会、日本がん予防学会、環境ホルモン学会、環境科学会 | |||||||||
| 社会活動 | ||||||||||
| 職歴 | 1992.04～1994.03 日本学術振興会特別研究員 PD
2001.10～2005.03 三重大学 医学部 教員 講師 |
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| 学術（芸術）賞 | 日本光医学・光生物学会奨励賞,日本光医学・光生物学会
三重大学医学部・大学院医学系研究科教育貢献賞,三重大学医学部・大学院医学系研究科 日本衛生学会奨励賞,日本衛生学会 日本環境変異原学会奨励賞,日本環境変異原学会 「科研費」審査委員表彰 |
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| 専門分野 | 環境医学 | |||||||||
| 現在の研究課題 | 酸化ストレスによる老化促進および発がん機構の解明 | |||||||||
| 担当科目 | 衛生学 環境生命科学 高齢社会と医療 社会医学集中講義 生物資源学部 公衆衛生学 | |||||||||
| 主な業績等 | H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion 共著 2007 Cell. Phyisol. Biochem.
9-Nitroanthracene derivative as a precursor of anthraquinone for photodynamic therapy 2007.03 Bioorg Med Chem. Mechanism of oxidative DNA damage induced by capsaicin, a principal ingredient of hot chili pepper. 共著 2006.09 Free Radic Res. 9 966-973 Proteomic analysis for protein carbonyl as an indicator of oxidative damage in senescence-accelerated mice. 共著 2006.11 Free Radic Res. 11 1173-1181 Mechanism for manganese enhancement of dopamine-induced oxidative DNA damage and neuronal cell death. 共著 2006.09 Free Radic Biol Med. 4 523-531 Mechanism of DNA damage and apoptosis induced by tetrahydropapaveroline, a metabolite of dopamine. 共著 2006.04 Neurochem Res. 4 523-532 iNOS-dependent DNA damage via NF-kappaB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel. 共著 2006.09 Int J Cancer. 5 1067-1072 Radical production and DNA damage induced by carcinogenic 4-hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus. 共著 2006.01 Free Radic Res. 1 31-39 Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure. 共著 2006.02 Cardiovasc Res. 3 726-735 Mechanism of metal-mediated DNA damage and apoptosis induced by 6-hydroxydopamine in neuroblastoma SH-SY5Y cells. 2008.07 Free radical research 42 651-60 Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine in patients with parasite infection and effect of antiparasitic drug in relation to cholangiocarcinogenesis. 2008.03 Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the 17 518-24 Mechanism of Oxidative DNA Damage Induced by Environmental Carcinogens and Antioxidants 2008 Genes Environ 30 1-9 The role of lysosomal rupture in neuronal death. 2009.12 Progress in neurobiology 89 343-58 DNA damage and apoptosis induced by photosensitization of 5,10,15,20-tetrakis (N-methyl-4-pyridyl)-21H,23H-porphyrin via singlet oxygen generation. 2009.11 Photochemistry and photobiology 85 1391-9 Proteomic identification of carbonylated proteins in the monkey hippocampus after ischemia-reperfusion. 2009.06 Free radical biology & medicine 46 1472-7 Damage to cellular and isolated DNA induced by a metabolite of aspirin. 2009.02 Mutation research 661 93-100 The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease. 2009.01 Journal of neurochemistry 108 397-407 Oxidatively generated DNA damage induced by 3-amino-5-mercapto-1,2,4-triazole, a metabolite of carcinogenic amitrole. 2010.12 Mutation research 694 7-12 Suppressed phosphorylation of collapsin response mediator protein-2 in the hippocampus of HCNP precursor transgenic mice. 2010.10 Brain research 1355 180-8 Proteomic analysis of aging brain in SAMP10 mouse: a model of age-related cerebral degeneration. 2010.06 Mechanisms of ageing and development 131 379-88 Evaluation for safety of antioxidant chemopreventive agents. 2005.11 Antioxidants & redox signaling 7 1728-39 Oxidative DNA damage in relation to neurotoxicity in the brain of mice exposed to arsenic at environmentally relevant levels. 2005.09 Journal of occupational health 47 445-9 Procyanidin B2 has anti- and pro-oxidant effects on metal-mediated DNA damage. 2005.10 Free radical biology & medicine 39 1041-9 Nitrative and oxidative DNA damage in oral lichen planus in relation to human oral carcinogenesis. 2005.09 Cancer science 96 553-9 Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion. 2005.08 World journal of gastroenterology : WJG 11 4644-9 Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C. 2005.09 Journal of hepatology 43 403-10 Sequence-specific DNA damage by reactive oxygen species: Implications for carcinogenesis and aging. 2005.03 Environmental health and preventive medicine 10 65-71 Guanine-specific DNA damage induced by gamma-irradiated histone. 2005.06 The Biochemical journal 388 813-8 Chemopreventive action of xanthone derivatives on photosensitized DNA damage. 2005.03 Photochemistry and photobiology 81 314-9 Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal model of dilated cardiomyopathy. 2006.11 Biochemical and biophysical research communications 350 105-13 DNA damage and estrogenic activity induced by the environmental pollutant 2-nitrotoluene and its metabolite. 2010.09 Environmental health and preventive medicine 15 319-26 Nitrative DNA damage and Oct3/4 expression in urinary bladder cancer with Schistosoma haematobium infection. 2011.10 Biochemical and biophysical research communications 414 344-9 Proteomic analysis of hippocampal proteins of F344 rats exposed to 1-bromopropane. 2011.11 Toxicology and applied pharmacology 257 93-101 Astrocytic neuroprotection through induction of cytoprotective molecules; a proteomic analysis of mutant P301S tau-transgenic mouse. 2011.09 Brain research 1410 12-23 Proteomic identification of hippocampal proteins vulnerable to oxidative stress in excitotoxin-induced acute neuronal injury. 2011.09 Neurobiology of disease 43 706-14 Altered gene and protein expression in liver of the obese spontaneously hypertensive/NDmcr-cp rat. 共著 2012 Nutr Metab (Lond). 9(1):87 Proteomic identification of carbonylated proteins in F344 rat hippocampus after 1-bromopropane exposure. 共著 2012 263 44-52 Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma. 共著 2012 Cancer Lett. 323 147-154 nflammation-induced protein carbonylation contributes to poor prognosis for cholangiocarcinoma. 共著 2012 Free Radic Biol Med. 52 1465-1472 Nuclear localization of COX-2 in relation to the expression of stemness markers in urinary bladder cancer. 共著 2012 Mediators Inflamm. 2012, 165879, Proton pump inhibitors suppress iNOS-dependent DNA damage in Barrett's esophagus by increasing Mn-SOD expression. 単著 2012 Biochem. Biophys. Res. Commun. 421 280-286 Inflammation-related DNA damage and expression of CD133 and Oct3/4 in cholangiocarcinoma patients with poor prognosis. 共著 2013 Free Radic Biol Med 65 1464-1472 Proteomic analysis of carbonylated proteins in the monkey substantia nigra after ischemia-reperfusion. 共著 2014 Free Radic Res. 48 694-705 Relationships of alpha-SMA-positive fibroblasts and SDF-1-positive tumor cells with neoangiogenesis in nasopharyngeal carcinoma. 共著 2014 Biomed Res Int. 2014: 507353 Oxidative Stress and Its Significant Roles in Neurodegenerative Diseases and Cancer. 共著 2014 Int J Mol Sci. 16 193-217 Nile blue can photosensitize DNA damage through electron transfer 共著 2014 Chem Res Toxicol. 27 649-655 Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat. 共著 2014 Diabetol Metab Syndr. 27;6(1):8, The potent tumor suppressor miR-497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L. 共著 2015 Oncotarget. 6 35893-35907 Oxidative DNA damage induced by metabolites of chloramphenicol, an antibiotic drug 共著 2015 Free Radic Res. 49 1165-1172 Circulating microRNAs as novel prognosis biomarkers for head and neck squamous cell carcinoma. 共著 2015 Cancer Biol Ther. 16 1042-1046 Melatonin induces apoptosis in cholangiocarcinoma cell lines by activating the reactive oxygen species-mediated mitochondrial pathway 共著 2015 Oncol Rep. 33 1443-1449 Hippocampal phosphoproteomics of F344 rats exposed to 1-bromopropane. 共著 2015 Toxicol Appl Pharmacol. 282 151-160 Inflammation-Related DNA Damage and Cancer Stem Cell Markers in Nasopharyngeal Carcinoma. 共著 2016 Mediators Inflamm. 2016:9343460 紫外線によるテロメア短縮促進機構, 共著 2016 光老化科学の最前線, シーエムシー出版 114-122 Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer's disease. 共著 2017 Neurol Res. 39 231-238 Involvement of oxidative modification of proteins related to ATP synthesis in the left ventricles of hamsters with cardiomyopathy 共著 2017 Sci Rep. 23, 7:9243 Quantitation of DNA methylation in Epstein-Barr virus-associated nasopharyngeal carcinoma by bisulfite amplicon sequencing. 共著 2017 BMC Cancer. 17, 17:489, RERG suppresses cell proliferation, migration and angiogenesis through ERK/NF-κB signaling pathway in nasopharyngeal carcinoma. 共著 2017 J Exp Clin Cancer Res. 28, 36:88 Nitrative and oxidative DNA damage in infection-related carcinogenesis in relation to cancer stem cells. 共著 2017 Genes Environ. 38:26, Complement Activation in Capillary Cerebral Amyloid Angiopathy 共著 2017 Dement Geriatr Cogn Disord. 44 343-353 Overexpression of CD44 Variant 9: A Novel Cancer Stem Cell Marker in Human Cholangiocarcinoma in Relation to Inflammation. 共著 2018 Mediators Inflamm. 2018:4867234, Proteomic Profiling of Exosomal Proteins for Blood-based Biomarkers in Parkinson's Disease. 共著 2018 Neuroscience. 392:121-128, 392 121-128 Taurine exhibits an apoptosis-inducing effect on human nasopharyngeal carcinoma cells through PTEN/Akt pathways in vitro. 共著 2018 Amino Acids. 2018, doi: 10.1007/s00726-018-2651-2. Let-7c inhibits migration and epithelial-mesenchymal transition in head and neck squamous cell carcinoma by targeting IGF1R and HMGA2 共著 2018 Oncotarget. 9 8927-8940 Mechanism of oxidative DNA damage induced by metabolites of carcinogenic naphthalene 共著 2018 Mutat Res. 827 42-49 Proteomics analysis identified peroxiredoxin 2 involved in early-phase left ventricular impairment in hamsters with cardiomyopathy 単著 2018 PLoS One. 13(2):e0192624 Nitrative DNA damage in cultured macrophages exposed to indium oxide. 共著 2018 J Occup Health 60 148-155 Mechanisms of DNA damage induced by morin, an inhibitor of amyloid β-peptide aggregation. 共著 2019.01 Free Radic Res. 53 115-123 Proteomic analysis of hippocampal proteins in acrylamide-exposed Wistar rats. 共著 2019.07 Arch Toxicol. 93 1993-2006 Anti-Cancer Mechanisms of Taurine in Human Nasopharyngeal Carcinoma Cells 共著 2019 Adv Exp Med Biol. 2019;1155:533-541 Proteomic analysis of liver proteins of mice exposed to 1,2-dichloropropane. 共著 2020.08 Arch Toxicol. 94 2691-2705 Taurine Attenuates Carcinogenicity in Ulcerative Colitis-Colorectal Cancer Mouse Model. 共著 2020.05 Oxid Med Cell Longev. 20;2020:7935917. CD44v9 Induces Stem Cell-Like Phenotypes in Human Cholangiocarcinoma. 共著 2020.06 Front Cell Dev Biol. 3;8:417 Nitrative DNA damage in lung epithelial cells exposed to indium nanoparticles and indium ions. 共著 2020.07 Sci Rep. 10(1):10741. Proteomic analysis of the monkey hippocampus for elucidating ischemic resistance 共著 2020.09 J Clin Biochem Nutr. 67 167-173 Proteomic identification of the proteins related to cigarette smoke-induced cardiac hypertrophy in spontaneously hypertensive rats. 共著 2020.11 Sci Rep. 2;10(1):18825 Polyphenols with Anti-Amyloid β Aggregation Show Potential Risk of Toxicity Via Pro-Oxidant Properties. 共著 2020.05 Int J Mol Sci. 18;21(10):3561. Chemopreventive action of xanthone derivatives on photosensitized DNA damage. 2005.03 Photochemistry and photobiology 81 314-9 Sequence-specific DNA damage by reactive oxygen species: Implications for carcinogenesis and aging. 2005.03 Environmental health and preventive medicine 10 65-71 Guanine-specific DNA damage induced by gamma-irradiated histone. 2005.06 The Biochemical journal 388 813-8 Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion. 2005.08 World journal of gastroenterology : WJG 11 4644-9 Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C. 2005.09 Journal of hepatology 43 403-10 Nitrative and oxidative DNA damage in oral lichen planus in relation to human oral carcinogenesis. 2005.09 Cancer science 96 553-9 Oxidative DNA damage in relation to neurotoxicity in the brain of mice exposed to arsenic at environmentally relevant levels. 2005.09 Journal of occupational health 47 445-9 Procyanidin B2 has anti- and pro-oxidant effects on metal-mediated DNA damage. 2005.10 Free radical biology & medicine 39 1041-9 Evaluation for safety of antioxidant chemopreventive agents. 2005.11 Antioxidants & redox signaling 7 1728-39 Radical production and DNA damage induced by carcinogenic 4-hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus. 共著 2006.01 Free Radic Res. 1 31-39 Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure. 共著 2006.02 Cardiovasc Res. 3 726-735 Mechanism of DNA damage and apoptosis induced by tetrahydropapaveroline, a metabolite of dopamine. 共著 2006.04 Neurochem Res. 4 523-532 iNOS-dependent DNA damage via NF-kappaB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel. 共著 2006.09 Int J Cancer. 5 1067-1072 Mechanism for manganese enhancement of dopamine-induced oxidative DNA damage and neuronal cell death. 共著 2006.09 Free Radic Biol Med. 4 523-531 Mechanism of oxidative DNA damage induced by capsaicin, a principal ingredient of hot chili pepper. 共著 2006.09 Free Radic Res. 9 966-973 Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal model of dilated cardiomyopathy. 2006.11 Biochemical and biophysical research communications 350 105-13 Proteomic analysis for protein carbonyl as an indicator of oxidative damage in senescence-accelerated mice. 共著 2006.11 Free Radic Res. 11 1173-1181 H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion 共著 2007 Cell. Phyisol. Biochem. 9-Nitroanthracene derivative as a precursor of anthraquinone for photodynamic therapy 2007.03 Bioorg Med Chem. Mechanism of Oxidative DNA Damage Induced by Environmental Carcinogens and Antioxidants 2008 Genes Environ 30 1-9 Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine in patients with parasite infection and effect of antiparasitic drug in relation to cholangiocarcinogenesis. 2008.03 Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the 17 518-24 Mechanism of metal-mediated DNA damage and apoptosis induced by 6-hydroxydopamine in neuroblastoma SH-SY5Y cells. 2008.07 Free radical research 42 651-60 The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease. 2009.01 Journal of neurochemistry 108 397-407 Damage to cellular and isolated DNA induced by a metabolite of aspirin. 2009.02 Mutation research 661 93-100 Proteomic identification of carbonylated proteins in the monkey hippocampus after ischemia-reperfusion. 2009.06 Free radical biology & medicine 46 1472-7 DNA damage and apoptosis induced by photosensitization of 5,10,15,20-tetrakis (N-methyl-4-pyridyl)-21H,23H-porphyrin via singlet oxygen generation. 2009.11 Photochemistry and photobiology 85 1391-9 The role of lysosomal rupture in neuronal death. 2009.12 Progress in neurobiology 89 343-58 Proteomic analysis of aging brain in SAMP10 mouse: a model of age-related cerebral degeneration. 2010.06 Mechanisms of ageing and development 131 379-88 DNA damage and estrogenic activity induced by the environmental pollutant 2-nitrotoluene and its metabolite. 2010.09 Environmental health and preventive medicine 15 319-26 Suppressed phosphorylation of collapsin response mediator protein-2 in the hippocampus of HCNP precursor transgenic mice. 2010.10 Brain research 1355 180-8 Oxidatively generated DNA damage induced by 3-amino-5-mercapto-1,2,4-triazole, a metabolite of carcinogenic amitrole. 2010.12 Mutation research 694 7-12 Astrocytic neuroprotection through induction of cytoprotective molecules; a proteomic analysis of mutant P301S tau-transgenic mouse. 2011.09 Brain research 1410 12-23 Proteomic identification of hippocampal proteins vulnerable to oxidative stress in excitotoxin-induced acute neuronal injury. 2011.09 Neurobiology of disease 43 706-14 Nitrative DNA damage and Oct3/4 expression in urinary bladder cancer with Schistosoma haematobium infection. 2011.10 Biochemical and biophysical research communications 414 344-9 Proteomic analysis of hippocampal proteins of F344 rats exposed to 1-bromopropane. 2011.11 Toxicology and applied pharmacology 257 93-101 Altered gene and protein expression in liver of the obese spontaneously hypertensive/NDmcr-cp rat. 共著 2012 Nutr Metab (Lond). 9(1):87 nflammation-induced protein carbonylation contributes to poor prognosis for cholangiocarcinoma. 共著 2012 Free Radic Biol Med. 52 1465-1472 Nuclear localization of COX-2 in relation to the expression of stemness markers in urinary bladder cancer. 共著 2012 Mediators Inflamm. 2012, 165879, Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma. 共著 2012 Cancer Lett. 323 147-154 Proteomic identification of carbonylated proteins in F344 rat hippocampus after 1-bromopropane exposure. 共著 2012 263 44-52 Proton pump inhibitors suppress iNOS-dependent DNA damage in Barrett's esophagus by increasing Mn-SOD expression. 単著 2012 Biochem. Biophys. Res. Commun. 421 280-286 Inflammation-related DNA damage and expression of CD133 and Oct3/4 in cholangiocarcinoma patients with poor prognosis. 共著 2013 Free Radic Biol Med 65 1464-1472 Expression of proteins associated with adipocyte lipolysis was significantly changed in the adipose tissues of the obese spontaneously hypertensive/NDmcr-cp rat. 共著 2014 Diabetol Metab Syndr. 27;6(1):8, Nile blue can photosensitize DNA damage through electron transfer 共著 2014 Chem Res Toxicol. 27 649-655 Oxidative Stress and Its Significant Roles in Neurodegenerative Diseases and Cancer. 共著 2014 Int J Mol Sci. 16 193-217 Proteomic analysis of carbonylated proteins in the monkey substantia nigra after ischemia-reperfusion. 共著 2014 Free Radic Res. 48 694-705 Relationships of alpha-SMA-positive fibroblasts and SDF-1-positive tumor cells with neoangiogenesis in nasopharyngeal carcinoma. 共著 2014 Biomed Res Int. 2014: 507353 Circulating microRNAs as novel prognosis biomarkers for head and neck squamous cell carcinoma. 共著 2015 Cancer Biol Ther. 16 1042-1046 Hippocampal phosphoproteomics of F344 rats exposed to 1-bromopropane. 共著 2015 Toxicol Appl Pharmacol. 282 151-160 Melatonin induces apoptosis in cholangiocarcinoma cell lines by activating the reactive oxygen species-mediated mitochondrial pathway 共著 2015 Oncol Rep. 33 1443-1449 Oxidative DNA damage induced by metabolites of chloramphenicol, an antibiotic drug 共著 2015 Free Radic Res. 49 1165-1172 The potent tumor suppressor miR-497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L. 共著 2015 Oncotarget. 6 35893-35907 Inflammation-Related DNA Damage and Cancer Stem Cell Markers in Nasopharyngeal Carcinoma. 共著 2016 Mediators Inflamm. 2016:9343460 紫外線によるテロメア短縮促進機構, 共著 2016 光老化科学の最前線, シーエムシー出版 114-122 Complement Activation in Capillary Cerebral Amyloid Angiopathy 共著 2017 Dement Geriatr Cogn Disord. 44 343-353 Involvement of oxidative modification of proteins related to ATP synthesis in the left ventricles of hamsters with cardiomyopathy 共著 2017 Sci Rep. 23, 7:9243 Nitrative and oxidative DNA damage in infection-related carcinogenesis in relation to cancer stem cells. 共著 2017 Genes Environ. 38:26, Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer's disease. 共著 2017 Neurol Res. 39 231-238 Quantitation of DNA methylation in Epstein-Barr virus-associated nasopharyngeal carcinoma by bisulfite amplicon sequencing. 共著 2017 BMC Cancer. 17, 17:489, RERG suppresses cell proliferation, migration and angiogenesis through ERK/NF-κB signaling pathway in nasopharyngeal carcinoma. 共著 2017 J Exp Clin Cancer Res. 28, 36:88 Nitrative DNA damage in cultured macrophages exposed to indium oxide. 共著 2018 J Occup Health 60 148-155 Let-7c inhibits migration and epithelial-mesenchymal transition in head and neck squamous cell carcinoma by targeting IGF1R and HMGA2 共著 2018 Oncotarget. 9 8927-8940 Mechanism of oxidative DNA damage induced by metabolites of carcinogenic naphthalene 共著 2018 Mutat Res. 827 42-49 Overexpression of CD44 Variant 9: A Novel Cancer Stem Cell Marker in Human Cholangiocarcinoma in Relation to Inflammation. 共著 2018 Mediators Inflamm. 2018:4867234, Proteomic Profiling of Exosomal Proteins for Blood-based Biomarkers in Parkinson's Disease. 共著 2018 Neuroscience. 392:121-128, 392 121-128 Proteomics analysis identified peroxiredoxin 2 involved in early-phase left ventricular impairment in hamsters with cardiomyopathy 単著 2018 PLoS One. 13(2):e0192624 Taurine exhibits an apoptosis-inducing effect on human nasopharyngeal carcinoma cells through PTEN/Akt pathways in vitro. 共著 2018 Amino Acids. 2018, doi: 10.1007/s00726-018-2651-2. Anti-Cancer Mechanisms of Taurine in Human Nasopharyngeal Carcinoma Cells 共著 2019 Adv Exp Med Biol. 2019;1155:533-541 Mechanisms of DNA damage induced by morin, an inhibitor of amyloid β-peptide aggregation. 共著 2019.01 Free Radic Res. 53 115-123 Proteomic analysis of hippocampal proteins in acrylamide-exposed Wistar rats. 共著 2019.07 Arch Toxicol. 93 1993-2006 Polyphenols with Anti-Amyloid β Aggregation Show Potential Risk of Toxicity Via Pro-Oxidant Properties. 共著 2020.05 Int J Mol Sci. 18;21(10):3561. Taurine Attenuates Carcinogenicity in Ulcerative Colitis-Colorectal Cancer Mouse Model. 共著 2020.05 Oxid Med Cell Longev. 20;2020:7935917. CD44v9 Induces Stem Cell-Like Phenotypes in Human Cholangiocarcinoma. 共著 2020.06 Front Cell Dev Biol. 3;8:417 Nitrative DNA damage in lung epithelial cells exposed to indium nanoparticles and indium ions. 共著 2020.07 Sci Rep. 10(1):10741. Proteomic analysis of liver proteins of mice exposed to 1,2-dichloropropane. 共著 2020.08 Arch Toxicol. 94 2691-2705 Proteomic analysis of the monkey hippocampus for elucidating ischemic resistance 共著 2020.09 J Clin Biochem Nutr. 67 167-173 Proteomic identification of the proteins related to cigarette smoke-induced cardiac hypertrophy in spontaneously hypertensive rats. 共著 2020.11 Sci Rep. 2;10(1):18825 Chemopreventive action of xanthone derivatives on photosensitized DNA damage. 2005.03 Photochemistry and photobiology 81 314-9 Sequence-specific DNA damage by reactive oxygen species: Implications for carcinogenesis and aging. 2005.03 Environmental health and preventive medicine 10 65-71 Guanine-specific DNA damage induced by gamma-irradiated histone. 2005.06 The Biochemical journal 388 813-8 Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion. 2005.08 World journal of gastroenterology : WJG 11 4644-9 Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C. 2005.09 Journal of hepatology 43 403-10 Nitrative and oxidative DNA damage in oral lichen planus in relation to human oral carcinogenesis. 2005.09 Cancer science 96 553-9 Oxidative DNA damage in relation to neurotoxicity in the brain of mice exposed to arsenic at environmentally relevant levels. 2005.09 Journal of occupational health 47 445-9 Procyanidin B2 has anti- and pro-oxidant effects on metal-mediated DNA damage. 2005.10 Free radical biology & medicine 39 1041-9 Evaluation for safety of antioxidant chemopreventive agents. 2005.11 Antioxidants & redox signaling 7 1728-39 Radical production and DNA damage induced by carcinogenic 4-hydrazinobenzoic acid, an ingredient of mushroom Agaricus bisporus. 共著 2006.01 Free Radic Res. 1 31-39 Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure. 共著 2006.02 Cardiovasc Res. 3 726-735 Mechanism of DNA damage and apoptosis induced by tetrahydropapaveroline, a metabolite of dopamine. 共著 2006.04 Neurochem Res. 4 523-532 iNOS-dependent DNA damage via NF-kappaB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel. 共著 2006.09 Int J Cancer. 5 1067-1072 Mechanism for manganese enhancement of dopamine-induced oxidative DNA damage and neuronal cell death. 共著 2006.09 Free Radic Biol Med. 4 523-531 Mechanism of oxidative DNA damage induced by capsaicin, a principal ingredient of hot chili pepper. 共著 2006.09 Free Radic Res. 9 966-973 Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal model of dilated cardiomyopathy. 2006.11 Biochemical and biophysical research communications 350 105-13 Proteomic analysis for protein carbonyl as an indicator of oxidative damage in senescence-accelerated mice. 共著 2006.11 Free Radic Res. 11 1173-1181 H2O2 accelerates cellular senescence by accumulation of acetylated p53 via decrease in the function of SIRT1 by NAD+ depletion 共著 2007 Cell. Phyisol. Biochem. 9-Nitroanthracene derivative as a precursor of anthraquinone for photodynamic therapy 2007.03 Bioorg Med Chem. 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