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三重大学教員紹介

教員情報

職名
教授
氏名
みぞぐち あきら
溝口 明
生年月
1953.08
所属
部局
医学系研究科
学科・専攻
生命医科学専攻
講座
基礎医学系講座
教育研究分野
 
TEL
 
FAX
059-231-5263
E-mail
amizomie@doc.medic. (末尾に mie-u.ac.jp を補ってください)
個人のホームページ
 
学歴
神戸大学医学部 学士課程 (~1980年)
神戸大学医学部大学院 博士課程・博士後期課程 (~1984年) 卒業・修了
学位
1984.03 医学博士 神戸大学
所属学会
日本解剖学会 日本組織細胞化学会 日本神経科学学会 日本電子顕微鏡学会 日本生化学学会
社会活動
 
職歴
1984.12~1989.09 神戸大学医学部 助手
1989.10~1996.07 神戸大学医学部 講師 講師
1996.08~2001.01 京都大学大学院医学研究科 助教授 助教授
2001.02~ 三重大学医学部 教授 教授
学術(芸術)賞
 
専門分野
 
現在の研究課題
 
担当科目
分子生命体科学 ,組織学
主な業績等
Triple N-glycosylation in the long S5-P loop regulates the activation and trafficking of the Kv12.2 potassium channel. 共著 2009.11 J Biol Chem. 284 48 33139-33150
Rim2alpha Determines Docking and Priming States in Insulin Granule Exocytosis. 共著 2010.08 Cell Metab. 12 2 117-129
Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagella. 共著 2000.01 J Cell Sci. 113 Pt1 103-112
Prostaglandin D2 as a mediator of allergic asthma. 共著 2000.03 Science. 287 5460 2013-2017
Nectin-3, a new member of immunoglobulin-like cell adhesion molecules that shows homophilic and heterophilic cell-cell adhesion activities. 共著 2000.04 J Biol Chem. 275 14 10291-10299
Association of synapse-associated protein 90/ postsynaptic density-95-associated protein (SAPAP) with neurofilaments. 共著 2000.05 Genes Cells. 5 3 203-210
Localization of l-afadin at puncta adhaerentia-like junctions between the mossy fiber terminals and the dendritic trunks of pyramidal cells in the adult mouse hippocampus. 共著 2000.08 J Comp Neurol. 424 2 297-306
Role of rab GDP dissociation inhibitor alpha in regulating plasticity of hippocampal neurotransmission. 共著 2000.10 Proc Natl Acad Sci U S A. 97 21 11587-11592
Incorporation and differentiation of hippocampus-derived neural stem cells transplanted in injured adult rat retina. 共著 2000.12 Invest Ophthalmol Vis Sci. 41 13 4268-4274
Cellular localization of lipocalin-type prostaglandin D synthase (beta-trace) in the central nervous system of the adult rat. 共著 2000.12 J Comp Neurol. 428 1 62-78
Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice. 共著 2001.01 Science. 291 5502 319-322
An ADP-ribosylation factor GTPase-activating protein Git2-short/KIAA0148 is involved in subcellular localization of paxillin and actin cytoskeletal organization. 共著 2001.03 Mol Biol Cell. 645-662
Role of Rab3 GDP/GTP exchange protein in synaptic vesicle trafficking at the mouse neuromuscular junction. 共著 2001.05 Mol Biol Cell. 12 5 1421-1430
Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep. 共著 2001.09 Proc Natl Acad Sci U S A. 98 20 11674-11679
The membrane-anchored MMP inhibitor RECK is a key regulator of extracellular matrix integrity and angiogenesis. 共著 2001.12 Cell 107 6 789-800
Nectin: an adhesion molecule involved in formation of synapses. 共著 2002.02 J Cell Biol. 156 3 555-565
Cadherin regulates dendritic spine morphogenesis. 共著 2002.07 Neuron 35 1 77-89
Mouse model of cerebral aneurysm: experimental induction by renal hypertension and local hemodynamic changes. 共著 2002.07 Stroke. 33 7 1911-1915
Spontaneous muscle action potentials fail to develop without fetal-type acetylcholine receptors. 共著 2002.07 EMBO Rep. 3 7 674-681
A GDP/GTP exchange protein for the Rab3 small G protein family up-regulates a postdocking step of synaptic exocytosis in central synapses. 共著 2002.10 Proc Natl Acad Sci U S A. 99 22 14536-14541
Impaired adrenocorticotropic hormone response to bacterial endotoxin in mice deficient in prostaglandin E receptor EP1 and EP3 subtypes. 共著 2003.04 Proc Natl Acad Sci U S A. 100 7 4132-4137
Stem cell-derived neural stem/progenitor cell supporting factor is an autocrine/paracrine survival factor for neural stem/progenitor cells. 共著 2003.09 J Biol Chem. 278 3 35491-35500
Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient mice. 共著 2003.12 Nature Medicine 9 12 1477-1483
The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival. 共著 2004.01 J Neurosci. 24 1 43-52
A novel mode of action of an ArfGAP, AMAP2/PAG3/Papalpha, in Arf6 function. 共著 2004.07 J Biol Chem. 279 36 37677-37684
The targeted disruption of the MYPT1 gene results in embryonic lethality. 共著 2005.06 Transgenic Res. 14 3 337-340
Choroid plexus ependymal cells host neural progenitor cells in the rat. 共著 2006.01 Glia. 53 1 32-42
Protruding disordered loop of gC1qR is specifically exposed and related to antiapoptotic property in germ cell lineage. 共著 2006.12 Histochem Cell Biol. 126 6 665-677
Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer. 共著 2007.02 Nature Biotechnol 25 2 233-237
Impaired cerebellar development and function in mice lacking CAPS2, a protein involved in neurotrophin release. 共著 2007.03 J Neurosci. 27 10 2472-2482
Activity-induced protocadherin arcadlin regulates dendritic spine number by triggering N-cadherin endocytosis via TAO2beta and p38 MAP kinases. 共著 2007.11 Neuron 56 3 456-471
Establishment of cell polarity by afadin during the formation of embryoid bodies. 共著 2008.01 Genes Cells 13 1 79-90
Increased susceptibility to spontaneous lung cancer in mice lacking LIM-domain only 7. 共著 2009.02 Cancer Sci. WILEY Inter Science 100 4 608-616
Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis 共著 2009.04 Genes Cells. 14 4 445-456


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