教員紹介トップページへ

三重大学トップページへ

三重大学教員紹介

教員情報

職名
助教(研究科内講師)
氏名
いしい けんいちろう
石井 健一朗
生年月
1973.07
所属
部局
医学系研究科
学科・専攻
生命医科学専攻
講座
基礎医学系講座
教育研究分野
腫瘍病理学
TEL
059-232-1111(内線 6363)
FAX
059-231-5010
E-mail
kenishii@clin.medic. (末尾に mie-u.ac.jp を補ってください)
個人のホームページ
学歴
岐阜薬科大学 学士課程 (~1996年)
岐阜薬科大学 博士課程・博士後期課程 (~2001年) 卒業・修了
学位
2001.03 博士(薬学) 岐阜薬科大学
2009.07 博士(医学) 三重大学
所属学会
日本癌学会 日本泌尿器科学会 American Association for Cancer Research 環境ホルモン学会 泌尿器科分子・細胞研究会 Society for Basic Urologic Research 日本病理学会 日本ケミカルバイオロジー学会
社会活動
 
職歴
2001.09~2004.08 Vanderbilt University Researcher Research fellow
2004.09~2009.08 三重大学大学院医学系研究科 腎泌尿器外科学 教員 助教
2009.09~2011.04 三重大学大学院地域イノベーション学研究科 研究員 研究講師
2011.05~ 三重大学大学院医学系研究科 腫瘍病理学 教員 研究科内講師
学術(芸術)賞
 
専門分野
癌生物学、薬理学
現在の研究課題
癌関連線維芽細胞を標的にした新規治療戦略の開発
担当科目
 
主な業績等
Aminopeptidase N regulation by zinc in human prostate participates in tumor cell invasion. 共著 2001 International Journal of Cancer 92 49-54
Decrease of metallothionein and aminopeptidase N in renal cancer tissues. 共著 2001 Journal of Biochemistry 129 253-258
Extract from Serenoa repens suppresses the invasion activity of human urological cancer cells by inhibiting urokinase-type plasminogen activator. 共著 2001 Biological&Pharmaceutical Bulletin 24 188-190
Inhibition of Aminopeptidase N (AP-N) and urokinase-type plasminogen activator (uPA) by zinc suppresses the invasion activity in human urological cancer cells. 共著 2001 Biological&Pharmaceutical Bulletin 24 226-230
Effect of transforming growth factor α overexpression on urogenital organ development in mouse 共著 2010 Differentiation 80 82-88
Endodermal origin of bladder trigone inferred from mesenchymal-epithelial interactions 共著 2010 Journal of Urology 183 386-391
Structural changes in alpha1-adrenoceptor antagonist-treated human prostatic stroma 共著 2010 Clinical and Experimental Medicine 10 99-106
Androgen receptor W741C and T877A mutations in AIDL cells, an androgen independent subline of prostate cancer LNCaP cells. 共著 2011 Tumor Biology 32 1097-1102
Endocrine disrupter bisphenol A increases in situ estrogen production in mouse urogenital sinus. 共著 2011 Biology of Reproduction 84 734-742
Heterogeneous induction of carcinoma-associated fibroblast-like differentiation in normal human prostatic fibroblasts by co-culturing with prostate cancer cells. 共著 2011 Journal of Cellular Biochemistry 112 3604-3611
Low androgen sensitivity is associated with low levels of Akt phosphorylation in LNCaP-E9 cells. 共著 2011 Journal of Andrology
Manserin as a novel histochemical neuroendocrine marker in prostate cancer 共著 2011 Urologic Oncology
Naftopidil, a subtype selective alpha1-adrenoceptor antagonist, suppresses human prostate tumor growth by altering interactions between tumor cells and stroma 共著 2011 Cancer Prevention Research 4 87-96
Evidence that the prostate-specific antigen (PSA)/Zn2+ axis may play a role in human prostate cancer cell invasion. 共著 2004 Cancer Letters 207 79-87
NE-10 Neuroendocrine Cancer Promotes the LNCaP Xenograft Growth in Castrated Mice. 共著 2004 Cancer Research 64 5489-5495
Zinc and Metallothionein Levels and Expression of Zinc Transporters in Androgen Independent subline of LNCaP Cells. 共著 2004 Journal of Andrology 25 154-161
The history of tissue recombination technology: Current and Future research. :In: Challenges in Prostate Cancer II. 共著 2005 Bowsher, W. (Ed.) Blackwell 40-52
Use of Tissue Recombination to Predict Phenotypes of Transgenic Mouse Models of Prostate Carcinoma. 共著 2005 Laboratory Investigation 85 1086-1103
Forkhead Box A1 Regulates Prostate Ductal Morphogenesis and Promotes Epithelial Cell Maturation. 共著 2005 Development 132 3431-3443
Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype. 共著 2005 Prostate 63 369-384
The natural history of human prostate gland: morphometric and hitopathological analysis of Japanese men. 共著 2005 Prostate 65 355-364
Steroid Hormones Stimulate Human Prostate Cancer Progression and Metastasis 共著 2006 International Journal of Cancer 118 2123-2131
Androgen-dependent prostate epithelial cell selection by targeting ARR(2)PBneo to the LPB-Tag model of prostate cancer 共著 2006 Laboratory Investigation 86 1074-1088
Bisphenol A induces permanent squamous change in mouse prostatic epithelium. 共著 2007 Differentiation 75 745-756
Isolation and characterization of LNCaP sublines differing in hormone sensitivity. 共著 2007 Journal of Andrology 28 670-678
Proprotein convertases modulate budding and branching morphogenesis of rat ventral prostate. 共著 2007 International Journal of Developmental Biology 51 229-233
Role of stromal tenascin-C in mouse prostatic development and epithelial cell differentiation. 共著 2008 Developmental Biology 324 310-319
Naftopidil, a selective alpha-1 adrenoreptor antagonist, inhibits growth of human prostate cancer cells by G1 cell cycle arrest. 共著 2008 International Journal of Cancer 122 444-451
Improvement to predict tumorigenic phenotype of androgen-insensitive human LNCaP prostatic cancer cell subline in recombination with rat urogenital sinus mesenchyme. 共著 2008 Cancer Science 99 2435-2443
Adult urothelial transdifferentiation to prostate epithelia is mediated by paracrine TGF-ß signaling. 共著 2009 Differentiation 77 95-102
Evidence that androgen-independent stromal growth factor signals promote androgen-insensitive prostate cancer cell growth in vivo. 共著 2009 Endocrine-Related Cancer


教員紹介の掲載内容の更新はこちらから(学内のみ)


三重大学教員紹介の内容について無断転用を禁じます