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三重大学教員紹介

教員情報

職名
助教
氏名
かとう しんや
加藤 信哉
生年月
1966.07
所属
部局
地域イノベーション推進機構
学科・専攻
先端科学研究支援センター
講座
放射線科学・安全管理学部門
教育研究分野
 
TEL
059-231-6355
FAX
059-231-5034
E-mail
kato-shinya@doc.medic. (末尾に mie-u.ac.jp を補ってください)
個人のホームページ
 
学歴
愛媛大学大学院生物環境保全学専攻博士課程
高知大学大学院農芸化学専攻修士課程
高知大学農学部農芸化学科
学位
博士(生命システム科学)県立広島大学
所属学会
日本放射線安全管理学会
日本アイソトープ協会
製薬放射線カンファレンス
大学等放射線施設協議会
日本農芸化学会
社会活動
放射線取扱主任者
(第1種放射線取扱主任者、第1種作業環境測定士[放射性物質]、衛生工学衛生管理者)
職歴
大阪市立大学大学院医学研究科 放射性同位元素実験施設 研究員
県立広島大学生命環境学部生命科学科 細胞死制御工学研究室 ラボ主任研究員
(社)生物資源利用研究所 研究員
学術(芸術)賞
第10回日本抗加齢医学会総会優秀演題賞,無作為化二重盲検マッチドペア比較試験によるフラーレンのシワ改善効果の検証,2010.06
日本放射線安全管理学会第15回学術大会優秀ポスター賞,放射線管理区域における床表面汚染密度測定箇所の妥当性について,2016.12
専門分野
放射線安全管理学
応用生物化学
コロイド化学
現在の研究課題
1. 放射線による生体影響の脂質膜モデル(リポソーム)を用いた解析
2. 環境中のコロイド物質がヒトの手に触れたり体内に取りこまれた場合の挙動と有用性
担当科目
放射線業務従事者教育訓練(放射性同位元素の安全取扱い)
入門生物学
研究室研修のレビューワーと指導補助
主な業績等
【原著論文(査読あり)】
28. The stenosis of cerebral arteries and impaired brain glucose uptake by long-lasting inflammatory cytokine release from dermatitis, but rescued by anti-IL-1 therapy.
Shinya Kato, Yoshiaki Matsushima, Kento Mizutani, Fumihiro Kawakita, Masashi Fujimoto, Karin Okada, Makoto Kondo, Koji Habe, Hidenori Suzuki, Hitoshi Mizutani, Keiichi Yamanaka
Journal of Investigative Dermatology
in press (2018).

27. Radiosensitization by liposome-encapsulated fullerenes to mitochondria/DNA-damages on human melanoma cells.
Shinya Kato, Tetsuro Yoshimura, Nobuhiko Miwa
Journal of Nanoscience and Nanotechnology, 18 (6), 3775-3786 (2018).

26. The hydrogen-storing microporous silica 'Microcluster' reduces acetaldehyde contained in a distilled spirit.
Shinya Kato, Nobuhiko Miwa
Materials Science and Engineering C: Materials for Biological Applications, 69, 117-121 (2016).

25. Synergic carcinostatic effects of ascorbic acid and hyperthermia on Ehrlich ascites tumor cell.
Yasukazu Saitoh, Tomoya Yoshimoto, Shinya Kato, Nobuhiko Miwa
Experimental Oncology, 37(2), 94-99 (2015).

24. Antioxidant activities of nano-bubble hydrogen-dissolved water assessed by ESR and 2,2'-bipyridyl methods.
Shinya Kato, Daigo Matsuoka, Nobuhiko Miwa
Materials Science and Engineering C: Materials for Biological Applications, 53, 7-10 (2015).

23. Repressive effects of oat extracts on intracellular lipid-droplet formation in adipocytes and a three-dimensional subcutaneous adipose tissue model.
Shinya Kato, Yuko Kato, Hiroki Shibata, Yasukazu Saitoh, Nobuhiko Miwa
Materials Science and Engineering C: Materials for Biological Applications, 49, 269-273 (2015).

22. Enhanced radiosensitization by the cationic liposome-encapsulated thymidine analogue BrdU through the increased intracellular BrdU-uptake on human melanoma as compared to anionic or nonionic liposomal or free BrdU.
Shinya Kato, Masatsugu Kimura, Nobuhiko Miwa
Journal of Biomedical Nanotechnology, 10, 3280-3290 (2014).

21.Fullerene-C60 derivatives prevent UV-irradiation/TiO2-induced cytotoxicity on keratinocytes and 3D-skin tissues through antioxidant actions.
Shinya Kato, Hisae Aoshima, Yasukazu Saitoh, Nobuhiko Miwa.
Journal of Nanoscience and Nanotechnology,
14, 3285-3291 (2014)

20. Radiosensitization by fullerene-C60 dissolved in squalene on human malignant melanoma through lipid peroxidation and enhanced mitochondrial membrane potential.
Shinya Kato, Masatsugu Kimura, Nobuhiko Miwa
Radiation Physics and Chemistry, 97, 134-141 (2014).

19. Hydrogen water intake via tube-feeding for patients with pressure ulcer and its reconstructive effects on normal human skin cells in vitro.
Qiang Li, Shinya Kato, Daigo Matsuoka, Hiroshi Tanaka, Nobuhiko Miwa
Medicinal Gas Research, 3(1), 20 (2013).

18. Repressive Effects of a capacitive-resistive electric transfer (CRet) Hyperthermic Apparatus Combined with ProVitamin C on Intracellular Lipid-Droplets Formation in Adipocytes.
Shinya Kato, Yasukazu Saitoh, Nobuhiko Miwa.
International Journal of Hyperthermia,,29(1), 30-37 (2013).

17. Inhibitions by hydrogen-occluding silica microcluster to melanogenesis in human pigment cells and tyrosinase reaction.
Shinya Kato, Yasukazu Saitoh, Nobuhiko Miwa.
Journal of Nanoscience and Nanotechnology, 13(1), 52-59 (2013).

16. Enhanced radiosensitization by liposome-encapsulated pimonidazole for anticancer effects on human melanoma cells.
Shinya Kato, Masatsugu Kimura, Katsuhiro Kageyama, Hiroshi Tanaka, Nobuhiko Miwa.
Journal of Nanoscience and Nanotechnology, 12(6), 4472-4477 (2012).

15. Colloidal platinum in hydrogen-rich water exhibits radical-scavenging activity and improves blood fluidity.
Shinya Kato, Ryoji Hokama, Hajime Okayasu, Yasukazu Saitoh,Keizou Iwai ,Nobuhiko Miwa.
Journal of Nanoscience and Nanotechnology, 12(5), 4019-4027 (2012).

14. Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes.
Shinya Kato, Yasukazu Saitoh, Keizou Iwai, Nobuhiko Miwa.
Journal of Photochemistry and Photobiology. B, Biology, 106, 24-33 (2012).

13. Anticancer effects of 6-O-palmitoyl-ascorbate combined with a capacitive-resistive electric transfer hyperthermic apparatus as compared with ascorbate in relation to ascorbyl radical generation.
Shinya Kato, Ryoko Asada, Katsuhiro Kageyama, Yasukazu Saitoh, Nobuhiko Miwa.
Cytotechnology, 63, 425-435 (2011).

12. Fullerene-C60 incorporated in liposome exerts persistent hydroxyl radical-scavenging activity and cytoprotection in UVA/B-irradiated keratinocytes.
Shinya Kato, Hisae Aoshima, Yasukazu Saitoh, Nobuhiko Miwa.
Journal of Nanoscience and Nanotechnology, 11, 3814-3823 (2011).

11. Super-highly hydroxylated fullerene derivative protects human keratinocytes from UV-induced cell injuries together with the decreases in intracellular ROS generation and DNA damages.
Yasukazu Saitoh, Akifumi Miyanishi, Hiromi Mizuno, Shinya Kato, Hisae Aoshima, Ken Kokubo, Nobuhiko Miwa.
Journal of Photochemistry and Photobiology. B, Biology, 102, 69-76 (2011).

10. Fish collagen-containing drink is subcutaneously absorbed and attenuates the UVA-induced tissue-integrity destruction and DNA damages in 3D-human skin tissue model.
Shinya Kato, Hisakazu Matsui, Yasukazu Saitoh and Nobuhiko Miwa.
Journal of Functional Foods, 3(1), 50-55 (2011).

9. Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics.
Shinya Kato, Hikaru Taira, Hisae Aoshima, Yasukazu Saitoh, Nobuhiko Miwa.
Journal of Nanoscience and Nanotechnology, 10(10), 6769-6774 (2010).

8. Novel polyhydroxylated fullerene suppresses intracellular oxidative stress together with repression of intracellular lipid accumulation during the differentiation of OP9 preadipocytes into adipocytes.
Yasukazu Saitoh, Li Xiao, Hiromi Mizuno, Shinya Kato, Hisae Aoshima, Hikaru Taira, Ken Kokubo, Nobuhiko Miwa.
Free Radical Research, 44(9), 1072-1081 (2010).

7. Defensive effects of fullerene-C60/liposome complex against UVA-induced intracellular reactive oxygen species generation and cell death in human skin keratinocytes HaCaT, associated with intracellular uptake and extracellular excretion of fullerene-C60.
Shinya Kato, Risa Kikuchi, Hisae Aoshima, Yasukazu Saitoh, Nobuhiko Miwa.
Journal of Photochemistry and Photobiology. B, Biology, 98, 144-151 (2010).

6. Defensive effects of fullerene-C60 dissolved in squalane against the 2,4-nonadienal-induced cell injury in human skin keratinocytes HaCaT and wrinkle formation in 3D-human skin tissue model.
Shinya Kato, Hisae Aoshima, Yasukazu Saitoh, Nobuhiko Miwa.
Journal of Biomedical Nanotechnology, 6(1), 52-58 (2010).

5. Highly hydroxylated or γ-cyclodextrin-bicapped water-soluble derivative of fullerene: The antioxidant ability assessed by electron spin resonance method and β-carotene bleaching assay.
Shinya Kato, Hisae Aoshima, Yasukazu Saitoh, Nobuhiko Miwa.
Bioorganic & Medicinal Chemistry Letters, 19(18), 5293-5296 (2010).

4. Fullerene-C60/liposome complex: Defensive effects against UVA-induced damages in skin structure, nucleus and collagen type I/IV fibrils, and the permeability into human skin tissue.
Shinya Kato, Hisae Aoshima, Yasukazu Saitoh, Nobuhiko Miwa.
Journal of Photochemistry and Photobiology B: Biology, 98(1), 99-105 (2010).

3. Biological safety of LipoFullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and permeability into the human skin tissue.
Shinya Kato, Hisae Aoshima, Yasukazu Saitoh, Nobuhiko Miwa.
Basic & Clinical Pharmacology & Toxicology, 104(6), 483-487 (2009).

2. Biological safety of liposome-fullerene consisting of hydrogenated lecithin, glycine soja sterols, and fullerene-C60 uopn photocytotoxicity and bacterial reverse mutagenicity.
Shinya Kato, Hisae Aoshima, Yasukazu Saitoh, Nobuhiko Miwa.
Toxicology and Industrial Health, 25(3), 197-203 (2009).

1.Sedimentation behavior of dispersed particles of clay and silt in acidic and alkaline suspensions of inorganic materials from various volcanic ash soils.
Yukiya Horikawa, Shinya Kawachi, Toshimasa Honna.
Soil Science and Plant Nutrition, 50(1), 19-25 (2004).

【技術報告(査読なし)】
1. 放射線施設における床表面汚染定点測定箇所の簡単で安価な選定方法の検討
黒澤 俊人, 加藤 信哉, 苅田 修一
技術報告集第23号 ISSN 1348-1991, 15-18 (2015).

【総説(査読なし)】
3. 新規素材の美肌・抗老化・抗メタボ効能に関する化粧品・美肌サプリメントとしての研究開発動向~主に水素・白金・フラーレン・プロビタミンC/E・炭酸ガス・天然系抗酸化剤について~.
斉藤 靖和, 加藤 信哉, 肖 黎, 三羽 信比古.
隔月刊 コスメティックステージ, 5(1), 47-62 (2010).

2. フラーレン誘導体の化粧品としての効能開発と今後の展開~抗酸化作用と細胞死防御効果をベースとして~.
肖 黎, 河地 信哉, 寥 峰, 青島 央江、斉藤 靖和, 三羽 信比古.
隔月刊 コスメティックステージ, 1(7), 36-45 (2007).

1. カーボンナノ素材の皮膚メラニン抑制作用と化粧品への応用
肖 黎,鈴木 清香,河地 信哉,松林 賢司,平田 直之,斉藤 靖和,三羽 信比古:遠藤 守信,飯島 澄男
ナノカーボンハンドブック 第1編,第3章,3-7-2節 514-521 (2007).


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