| 教員紹介トップページへ | 三重大学トップページへ |
| 職名 | 教授 | |||||||||
| 氏名 | わたなべ まさとし 渡邉 昌俊 |
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| TEL | 059-231-5010 | |||||||||
| FAX | 059-232-2864 | |||||||||
| mawata@doc.medic. (末尾に mie-u.ac.jp を補ってください) | ||||||||||
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| 学歴 | 1983.3.横浜国立大学工学部 卒業
1989.3.三重大学医学部 卒業 1993.3.三重大学大学院医学研究科 博士後期課程 修了 |
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| 学位 | 1993.03 博士（医学） 三重大学
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| 所属学会 | 日本病理学会（病理専門医、分子病理専門医、学術評議員、刊行委員）、日本癌学会（評議員、Associate Editor）、日本臨床細胞学会（専門医）、日本臨床検査医学会（専門医、評議員）、 American Association for Cancer Research、 International Agency of Pathology、 日本消化器病学会、日本がん疫学・分子疫学研究会（功労会員）
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| 社会活動 | 日本病理学会・日本泌尿器科学会,前立腺癌取扱規約委員会、三重県死因究明等推進協議会委員、三重県がん登録事業運営部委員会委員、三重県がん対策推進協議会委員
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| 職歴 | 1993.04～1995.06 国立がんセンター研究所 リサーチレジデント
1995.07～1997.03 三重大学医学部 助手 1997.04～2003.03 三重大学医学部 助教授 1997.10～1999.06 NIH/NIEHS 文部省在外研究員・客員研究員 2003.04～2017.04 横浜国立大学大学院工学研究院 教授 2003.06～2017.03 三重大学医学部 非常勤 2003.11～2006.11 横浜市立大学医学部 客員教授 2011.11～2017.03 横浜市立大学医学部 客員教授 2022.4〜三重大学医学部附属病院・副院長（医学部連携担当） |
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| 学術（芸術）賞 | 前立腺がんワークショップ賞,2001.09
日本病理学会学術研究賞（秋期総会A演説）,2001.11 |
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| 専門分野 | 病理学、医工学、レギュラトリーサイエンス | |||||||||
| 現在の研究課題 | 前立腺腫瘍微小環境、新規in vitro培養系構築・標準化、ナノメディシン、ナノトキシコロジー | |||||||||
| 担当科目 | 病理学 | |||||||||
| 主な業績等 | Glycolytic Oscillations in HeLa Cervical Cancer Cell Spheroids. FEBS J. 2022 Apr. doi: 10.1111/febs.16454.
New horizons of DNA adductor for exploring environmental causes of cancer. Cancer Sci, 112(1), 7-15, 2021. Reduced tumorigenicity of mouse ES cells and the augmented anti-tumor therapeutic effects under Parg deficiency. Cancers, 12(4), 1056, 2020. Castration-induced stromal remodeling disrupts the reconstituted prostate epithelial structure. Laboratory Investigation 100(5), 670-681, 2020. Anti-fibrotic agent pirfenidone suppresses proliferation of human pancreatic cancer cells by inducing G0/G1 cell cycle arrest. Pharmacology, 103(5-6), 250-256, 2019. Pirfenidone, an anti-fibrotic drug, suppresses the growth of human prostate cancer cells by inducing G1 cell cycle arrest. J Clin Med, 8(1), 44, 2019. Primary cilia as signaling hubs in health and disease. Adv. Sci., 1801138, 2018 Predicting the tumorigenic phenotype of human bladder cancer cells by combining with fetal rat mesenchyme.Urol Oncol. 36(10), 472.e1-9, 2018 Association of HER2 gene amplification and tumor progression in early gastric cancer. Virchow Arch, 473(5), 559-565, 2018. Red blood cell-shaped microparticles with a red blood cell membrane demonstrate prolonged circulation time in blood. ACS Biomater. Sci.Eng., 4(8), 27729-2732, 2018. A nucleolar stress–specific p53–miR-101 molecular circuit functions as an intrinsic tumor-suppressor network. EbioMedicine, 33, 33-48, 2018. Measurement of poly(ADP-ribose) level with enhanced slot blot assay with crosslinking. Challenges, 9, 27, 2018. The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src. Oncogene,37, 5552-5568, 2018. Aberrant activation of epithelial-stromal interactions in proliferative prostatic diseases. J. Clin. Med. 7, 68, 2018. Establishment of an in vivo simulating co-culture assay platform for genotoxicity of multi-walled carbon nanotubes. Cancer Sci, 109(4), 1024-1031, 2018. Combined effects of Fe3O4 nanoparticles and chemotherapyeutic agents on prostate cancer cells in vitro. Applied Sciences, 8(1), 134, 2018. Primordial oscillations in life: Direct observantion of glycolytic oscillations in individual HeLa cervical cancer cells. Chaos.27, 104602, 2017. Effects of physicochemical character differences on the genotoxic potency of kaolin. Genes Environ, 39, 12, 2017. Pleiotropic functions of magnetic nanoparticles for ex vivo gene transfer. Nanomedicine, 10(6), 1165-1174, 2014. Development of a Novel Semi-Quantitative Analysis System for Ultramicroscale Samples by Fluorescent Capillary Isoelectric Focusing. Biosens Bioelectron, 54, 656-60, 2014. Magnetic nanoparticles of Fe3O4 enhance docetaxel-induced prostate cancer cell death. Int J Nanomed, 8, 3151-3160, 2013. Adiponectin suppresses colorectal carcinogenesis under the high-fat diet condition. Gut, 57(11), 1531-38, 2008. The Role of Epigenetic Modifications in Retinoic Acid Receptor β2 Gene Expression in Human Prostate Cancers. Lab Invest, 81(7), 1049-1057, 2001. Syncytiotrophoblastic giant cells in teratocarcinoma-like tumors derived from Parp-disrupted mouse embryonic stem cells. Pro Natl Acad Sci USA, 96(23), 13345-13350, 1999. Differences in the p53 gene mutational spectra of prostate cancers between Japan and Western countries. Carcinogenesis, 18(7), 1355-1358, 1997. Specific 5'-GGGA- to -5'GGA- mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Proc Natl Acad Sci USA, 92(3), 910-914, 1995. |
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