職名 准教授
氏名 やのゆたか
矢野  裕
生年月 1959.06
所属 部局 附属病院
学科・専攻 内科系診療科
講座 糖尿病・内分泌内科
教育研究分野  
TEL  
FAX  
E-mail yanoyuta@clin.medic. (末尾に mie-u.ac.jp を補ってください)
個人のホームページ  
学歴 三重大学医学部 学士課程 (~1985年)
三重大学大学院医学研究科内科学III 博士課程・博士後期課程 (~1990年) 卒業・修了
学位 1990.03 医学博士 三重大学
所属学会 日本内科学会 日本糖尿病学会 日本腎臓学会 糖尿病合併症学会 日本内分泌学会 日本病態栄養学会 日本甲状腺学会 日本肥満治療学会 日本肥満学会 糖尿病情報学会
社会活動 三重県糖尿病対策委員
雑誌さかえ編集委員


職歴  
学術(芸術)賞 東海学術奨励賞
三重大学大学院医学系研究科教育貢献賞
内科学会優秀演題賞
知的財産優秀出願賞,知的財産活動に対する成果,2015.09,三重大学
専門分野 内分泌代謝学
現在の研究課題 糖尿病性血管障害に対しての新規治療法の開発
担当科目 チュートリアルの系統講義、副甲状腺
修士講義 糖尿病と遺伝子 糖尿病の先端医療 糖尿病の病態と診断 糖尿病の病態と分子機構 糖尿病の薬物療法
主な業績等 Increased plasma thrombin-activatable fibrinolysis inhibitor levels in normotensive type 2 diabetic patients with microalbuminuria. 共著 2003.02 The Journal of clinical endocrinology and metabolism 88 736-41
Increased oxidative stress is associated with elevated plasma levels of adrenomedullin in hypertensive patients with type 2 diabetes. 共著 2003.05 Diabetes care 26 1642-3
Association between endothelial nitric oxide synthase Glu298Asp polymorphism and postchallenge insulin levels in nondiabetic Japanese subjects. 共著 2003.07 Diabetes care 26 2216-8
Nitric oxide stimulates glucose transport through insulin-independent GLUT4 translocation in 3T3-L1 adipocytes. 共著 2003.07 European journal of endocrinology / European Federation of Endocrine Societies 149 61-7
Increased visceral fat and serum levels of triglyceride are associated with insulin resistance in Japanese metabolically obese, normal weight subjects with normal glucose tolerance. 共著 2003.08 Diabetes care 26 2341-4
Oxidative stress is associated with adiposity and insulin resistance in men. 共著 2003.10 The Journal of clinical endocrinology and metabolism 88 4673-6
Plasma levels of adiponectin are associated with insulin resistance and serum levels of triglyceride in Japanese metabolically obese, normal-weight men with normal glucose tolerance. 共著 2003.10 Diabetes care 26 2964-5
Increased oxidative stress is associated with serum levels of triglyceride, insulin resistance, and hyperinsulinemia in Japanese metabolically obese, normal-weight men. 共著 2004.02 Diabetes care 27 631-2
Tumor necrosis factor-alpha is associated with increased protein C activation in nonobese type 2 diabetic patients. 共著 2004.03 Diabetes care 27 844-5
Circulating levels of active ghrelin is associated with abdominal adiposity, hyperinsulinemia and insulin resistance in patients with type 2 diabetes mellitus. 共著 2004.11 European journal of endocrinology / European Federation of Endocrine Societies 151 573-7
Presence of thrombin-activatable fibrinolysis inhibitor in Helicobacter pylori-associated gastroduodenal disease. 共著 2009.04 Helicobacter 14 147-55
A case of fulminant type 1 diabetes with coxsackie B4 virus infection diagnosed by elevated serum levels of neutralizing antibody. 共著 2009.06 Diabetes research and clinical practice 84 0-2
Direct effects of protein S in ameliorating acute lung injury. 共著 2009.12 Journal of thrombosis and haemostasis : JTH 7 2053-63
Inhibition of allergic bronchial asthma by thrombomodulin is mediated by dendritic cells. 共著 2011.01 American journal of respiratory and critical care medicine 183 31-42
Development and preclinical efficacy of novel transforming growth factor-beta1 short interfering RNAs for pulmonary fibrosis. 共著 2012.03 American journal of respiratory cell and molecular biology 46 397-406
Dose-dependent differential effects of thrombin in allergic bronchial asthma. 共著 2013.10 Journal of thrombosis and haemostasis : JTH 11 1903-15
Activated protein C modulates the proinflammatory activity of dendritic cells. 共著 2015.05 Journal of asthma and allergy 8 29-37
Effects of sugar-sweetened beverage intake on the development of type 2 diabetes mellitus in subjects with impaired glucose tolerance: the Mihama diabetes prevention study. 共著 2015.06 Journal of nutritional science and vitaminology 61 14-9
Amelioration of Atherosclerosis by the New Medicinal Mushroom Grifola gargal Singer. 共著 2015.08 Journal of medicinal food 18 872-81
Amelioration of Diabetes by Protein S. 共著 2016.07 Diabetes 65 1940-51
Association of Waist Circumference and Body Fat Weight with Insulin Resistance in Male Subjects with Normal Body Mass Index and Normal Glucose Tolerance. 共著 2016.07 Internal medicine (Tokyo, Japan) 55 1425-32
Comparison of Glucose Area Under the Curve Measured Using Minimally Invasive Interstitial Fluid Extraction Technology with Continuous Glucose Monitoring System in Diabetic Patients. 共著 2017.08 Diabetes & metabolism journal 41 265-274
Anti-apoptotic activity of human matrix metalloproteinase-2 attenuates diabetes mellitus. 共著 2018.05 Metabolism: clinical and experimental 82 88-99
Anti-inflammatory effect of activated protein C in gastric epithelial cells. 共著 2005.12 Journal of thrombosis and haemostasis : JTH 3 2721-9
Decreased circulating levels of active ghrelin are associated with increased oxidative stress in obese subjects. 共著 2005.09 European journal of endocrinology / European Federation of Endocrine Societies 153 403-7
Vacuolating cytotoxin A is associated with increased thrombin generation in gastric mucosa. 共著 2005.08 Helicobacter 10 323-31
Quantitative insulin sensitivity check index is a useful indicator of insulin resistance in Japanese metabolically obese, normal-weight subjects with normal glucose tolerance. 共著 2005.04 Endocrine journal 52 253-7
Metformin-induced suppression of glucose-6-phosphatase expression is independent of insulin signaling in rat hepatoma cells. 共著 2005.03 International journal of molecular medicine 15 449-52
Insulin enhanced thrombin-activable fibrinolysis inhibitor expression through PI3 kinase/Akt pathway. 共著 2005.02 International journal of molecular medicine 15 265-8
Decreased high-molecular weight adiponectin-to-total adiponectin ratio in sera is associated with insulin resistance in Japanese metabolically obese, normal-weight men with normal glucose tolerance 共著 2006 Diabetes Care. 29 2327-2328
Increased oxidative stress is associated with decreased circulating levels of adiponectin in Japanese metabolically obese, normal-weight men with normal glucose tolerance. 共著 2006.03 Diabetes Res Clin Pract 73 310-314
Thrombin-activatable fibrinolysis inhibitor deficiency attenuates bleomycin-induced lung fibrosis. 共著 2006.04 Am J Pathol. 168 1086-1096
Decreased protein C activation in patients with fulminant hepatic failure. 2006.03 Scand J Gastroenterol. 41 331-337
Different metabolic correlations of thrombin-activatable fibrinolysis inhibitor and plasminogen activator inhibitor-1 in non-obese type 2 diabetic patients. 共著 2006.02 Diabetes Res Clin Pract. 73 150-157
Inverse correlation between activated protein C generation and carotid atherosclerosis in Type 2 diabetic patients. 共著 2007.12 Diabet Med. 24 1322-1328
Monocyte chemoattractant protein-1 promoter -2518 polymorphism is associated with post-challenge insulin and glucose levels in non-diabetic Japanese subjects. 共著 2007.02 Diabetes Res Clin Pract 78 208-210
Role of thrombin in interleukin-5 expression from basophils. 共著 2008.03 Biochem Biophys Res Commun 368 116-120
Protective role of thrombin activatable fibrinolysis inhibitor in obstructive nephropathy-associated tubulointerstitial fibrosis. 共著 2008.01 J Thromb Haemost 6 139-146
Inhibition of nuclear factor-kappaB in T cells suppresses lung fibrosis. 共著 2007.12 Am J Respir Crit Care Med. 176 1251-1260
Role of the coagulation system in allergic inflammation in the upper airways. 2008.11 Clinical immunology (Orlando, Fla.) 129 365-71
Immune complex-mediated glomerulonephritis is ameliorated by thrombin-activatable fibrinolysis inhibitor deficiency. 共著 2008.07 Thrombosis and haemostasis 100 90-100
糖尿病性昏睡(高血糖高浸透圧症候群、乳酸アシドーシス) 単著 2008.01 今日の治療指針 2008年版 548-549
Role of thrombin in interleukin-5 expression from basophils. 共著 2008.03 Biochemical and biophysical research communications 368 116-20
Protective role of thrombin activatable fibrinolysis inhibitor in obstructive nephropathy-associated tubulointerstitial fibrosis. 共著 2008.01 Journal of thrombosis and haemostasis : JTH 6 139-46
尿中トランスフェリン 共著 2008.10 新時代の糖尿病学(4) 増刊号
三重医学研究振興会 単著
医科学応用研究財団研究報告書 共著
岡三加藤財団 単著