| 教員紹介トップページへ | 三重大学トップページへ |
| 職名 | 教授 | |||||||||
| 氏名 | おくがわ よしなが 奥川 喜永 |
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| TEL | 内線5645 | |||||||||
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| 現在の研究課題 | エピジェネテックスを介した消化管悪性腫瘍バイオマーカー研究と転移進展機序解明 | |||||||||
| 担当科目 | ||||||||||
| 主な業績等 | Brain-derived neurotrophic factor/tropomyosin-related kinase B pathway in gastric cancer. 2013.01 British journal of cancer 108 121-30
Prognostic significance of a systemic inflammatory response in patients undergoing multimodality therapy for advanced colorectal cancer. 2013 Oncology 84 100-7 Smad interacting protein 1 (SIP1) is associated with peritoneal carcinomatosis in intestinal type gastric cancer. 2013.04 Clinical & experimental metastasis 30 417-29 Cytoreductive strategy for multiple intra-abdominal and abdominal wall desmoid tumors in familial adenomatous polyposis: report of three cases. 2012.10 Clinical journal of gastroenterology 5 361-6 Significant correlation between LKB1 and LGR5 gene expression and the association with poor recurrence-free survival in rectal cancer after preoperative chemoradiotherapy. 2013.01 Journal of cancer research and clinical oncology 139 131-8 Clinical significance of LGR5 and CD44 expression in locally advanced rectal cancer after preoperative chemoradiotherapy. 2012.11 International journal of oncology 41 1643-52 In vivo real-time imaging of chemotherapy response on the liver metastatic tumor microenvironment using multiphoton microscopy. 2012.11 Oncology reports 28 1822-30 The prognostic value of KRAS mutations in patients with colorectal cancer. 2012.11 Oncology reports 28 1579-84 Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy. 2012.09 Oncology reports 28 855-61 Correlation of MACC1 and MET expression in rectal cancer after neoadjuvant chemoradiotherapy. 2012.04 Anticancer research 32 1527-31 Clinical significance of serum soluble E-cadherin in colorectal carcinoma. 2012.06 The Journal of surgical research 175 e67-73 In vivo time-course imaging of tumor angiogenesis in colorectal liver metastases in the same living mice using two-photon laser scanning microscopy. 2012 Journal of oncology 2012 265487- CXCL5, a promoter of cell proliferation, migration and invasion, is a novel serum prognostic marker in patients with colorectal cancer. 2012.09 European journal of cancer (Oxford, England : 1990) 48 2244-51 Clinical significance of Zinc finger E-box Binding homeobox 1 (ZEB1) in human gastric cancer. 2012.09 Journal of surgical oncology 106 280-5 Prognostic significance of glucose transporter-1 (GLUT1) gene expression in rectal cancer after preoperative chemoradiotherapy. 2012.05 Surgery today 42 460-9 TS and DPD mRNA levels on formalin-fixed paraffin-embedded specimens as predictors for distant recurrence of rectal cancer treated with preoperative chemoradiotherapy. 2012.05 Journal of surgical oncology 105 529-34 Inhibition of HGF/cMET expression prevents distant recurrence of rectal cancer after preoperative chemoradiotherapy. 2012.02 International journal of oncology 40 583-91 Intravital dual-colored visualization of colorectal liver metastasis in living mice using two photon laser scanning microscopy. 2012.03 Microscopy research and technique 75 307-15 Phase I study of 5-fluorouracil, leucovorin and bevacizumab in combination with radiation therapy in patients with locally advanced rectal cancer. 2013.05 Molecular and clinical oncology 1 511-516 C-reactive protein as predictor of recurrence in patients with rectal cancer undergoing chemoradiotherapy followed by surgery. 2013.11 Anticancer research 33 5065-74 Correlation of CCL20 expression in rectal mucosa with the development of ulcerative colitis-associated neoplasia. 2013.11 Oncology letters 6 1271-1276 Multimodality therapy in fistula-associated perianal mucinous adenocarcinoma. 2013.09 The American surgeon 79 e286-8 Single-port laparoscopic management of adhesive small bowel obstruction. 2014.03 Surgery today 44 586-90 Loss of the metastasis suppressor gene KiSS1 is associated with lymph node metastasis and poor prognosis in human colorectal cancer. 2013.09 Oncology reports 30 1449-54 Decreased expression of DUSP4 is associated with liver and lung metastases in colorectal cancer. 2013 Medical oncology (Northwood, London, England) 30 620- Identification of patients with developing ulcerative colitis-associated neoplasia by nitrative DNA damage marker 8-nitroguanin expression in rectal mucosa. 2013.10 Journal of clinical gastroenterology 47 e80-6 Trehalose does not affect the functions of human neutrophils in vitro. 2014.02 Surgery today 44 332-9 Chemoradiotherapy followed by restorative proctocolectomy with partial intersphincteric resection for advanced rectal cancer associated with ulcerative colitis: report of a case. 2014.02 Surgery today 44 387-90 Clinical implications of CES2 RNA expression in neuroblastoma. 2013.03 Journal of pediatric surgery 48 502-9 Leucine-rich repeat-containing G protein-coupled receptor 5 expression in ductular reactions after chemotherapy for metastatic colorectal cancer. 2013.01 Hepatology research : the official journal of the Japan Society of Hepatology 43 84-90 Prognostic significance of opioid use in the active treatment of advanced colorectal cancer. 2013.01 Molecular and clinical oncology 1 59-64 Brain-derived neurotrophic factor/tropomyosin-related kinase B pathway in gastric cancer. 2013.01 British journal of cancer 108 121-30 Prognostic significance of a systemic inflammatory response in patients undergoing multimodality therapy for advanced colorectal cancer. 2013 Oncology 84 100-7 Smad interacting protein 1 (SIP1) is associated with peritoneal carcinomatosis in intestinal type gastric cancer. 2013.04 Clinical & experimental metastasis 30 417-29 Significant correlation between LKB1 and LGR5 gene expression and the association with poor recurrence-free survival in rectal cancer after preoperative chemoradiotherapy. 2013.01 Journal of cancer research and clinical oncology 139 131-8 Macrophage inflammatory protein-3 alpha (MIP-3a) is a novel serum prognostic marker in patients with colorectal cancer. 2013.02 Journal of surgical oncology 107 160-6 Clinical implications of Fas/Fas ligand expression in patients with esophageal squamous cell carcinoma following neoadjuvant chemoradiotherapy. 2015.01 Molecular and clinical oncology 3 151-156 Conversion Therapy Using mFOLFOX6 With Panitumumab for Unresectable Liver Metastases From Multiple Colorectal Cancers With Familial Adenomatous Polyposis. 2014.11 International surgery 99 795-801 Puborectal sling interposition combined with seton drainage for pouch-vaginal fistula after rectal cancer surgery with colonic J pouch-anal reconstruction: report of a case. 2014.11 International surgery 99 710-3 In vivo characterization of neutrophil extracellular traps in various organs of a murine sepsis model. 2014 PloS one 9 e111888- Elevated serum angiopoietin-like protein 2 correlates with the metastatic properties of colorectal cancer: a serum biomarker for early diagnosis and recurrence. 2014.12 Clinical cancer research : an official journal of the American Association for Cancer Research 20 6175-86 Metastasis-associated long non-coding RNA drives gastric cancer development and promotes peritoneal metastasis. 2014.12 Carcinogenesis 35 2731-9 An update on microRNAs as colorectal cancer biomarkers: where are we and what's next? 2014.11 Expert review of molecular diagnostics 14 999-1021 DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer. 2014.12 Biochemical and biophysical research communications 455 43-57 Clinical significance of tartrate-resistant acid phosphatase type-5 expression in human gastric cancer. 2014.07 Anticancer research 34 3425-9 In vivo optical imaging of cancer metastasis using multiphoton microscopy: a short review. 2014 American journal of translational research 6 179-87 MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1. 2015.02 Gut 64 203-14 Low serum interleukin-13 levels correlate with poorer prognoses for colorectal cancer patients. 2014.05 International surgery 99 223-9 Brain-derived neurotrophic factor (BDNF)-induced tropomyosin-related kinase B (Trk B) signaling is a potential therapeutic target for peritoneal carcinomatosis arising from colorectal cancer. 2014 PloS one 9 e96410- Clinical significance of RacGAP1 expression at the invasive front of gastric cancer. 2015.01 Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 18 84-92 Lack of M30 expression correlates with factors reflecting tumor progression in rectal cancer with preoperative chemoradiotherapy. 2014.01 Molecular and clinical oncology 2 99-104 [MicroRNAs as non-invasive biomarkers for colorectal cancer: review]. 2014.03 Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 111 482-94 Single-port laparoscopic management of adhesive small bowel obstruction. 2014.03 Surgery today 44 586-90 Trehalose does not affect the functions of human neutrophils in vitro. 2014.02 Surgery today 44 332-9 Chemoradiotherapy followed by restorative proctocolectomy with partial intersphincteric resection for advanced rectal cancer associated with ulcerative colitis: report of a case. 2014.02 Surgery today 44 387-90 Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications. 2015.10 Scientific reports 5 14983- Serum angiopoietin-like protein 2 as a potential biomarker for diagnosis, early recurrence and prognosis in gastric cancer patients. 2015.12 Carcinogenesis 36 1474-83 Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers. 2015.10 Gastroenterology 149 1204-1225.e12 Efficacy and safety of laparoscopic surgery in elderly patients with colorectal cancer. 2015.07 Molecular and clinical oncology 3 897-901 Serum miR-21, miR-29a, and miR-125b Are Promising Biomarkers for the Early Detection of Colorectal Neoplasia. 2015.09 Clinical cancer research : an official journal of the American Association for Cancer Research 21 4234-42 Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer. 2015.05 Cancer prevention research (Philadelphia, Pa.) 8 431-43 Letter to the Editor: Intravital imaging of the association between intravascular neutrophil extracellular traps and microvascular obstruction using multiphoton microscopy. 2015.04 American journal of physiology. Heart and circulatory physiology 308 H960- Visualization of in vivo thromboprophylactic and thrombolytic efficacy of enoxaparin in laser-induced vascular endothelial injury model using multiphoton microscopy. 2015 American journal of translational research 7 79-87 Preoperative assessment of vascular anatomy by multidetector computed tomography before laparoscopic colectomy for transverse colon cancer: report of a case. 2015.02 International surgery 100 208-12 Elevated platelet count as predictor of recurrence in rectal cancer patients undergoing preoperative chemoradiotherapy followed by surgery. 2015.02 International surgery 100 199-207 Identification of a metastasis-specific MicroRNA signature in human colorectal cancer. 2015.03 Journal of the National Cancer Institute 107 Immunodeficiency and autoimmune enterocolopathy linked to NFAT5 haploinsufficiency. 2015.03 Journal of immunology (Baltimore, Md. : 1950) 194 2551-60 Curcumin mediates chemosensitization to 5-fluorouracil through miRNA-induced suppression of epithelial-to-mesenchymal transition in chemoresistant colorectal cancer. 2015.03 Carcinogenesis 36 355-67 Comparison of reduced-port and conventional laparoscopic total proctocolectomy with ileal J-pouch-anal anastomosis. 2015.02 The American surgeon 81 E70-2 Clinical implications of Fas/Fas ligand expression in patients with esophageal squamous cell carcinoma following neoadjuvant chemoradiotherapy. 2015.01 Molecular and clinical oncology 3 151-156 MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1. 2015.02 Gut 64 203-14 Clinical significance of RacGAP1 expression at the invasive front of gastric cancer. 2015.01 Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 18 84-92 RacGAP1 expression, increasing tumor malignant potential, as a predictive biomarker for lymph node metastasis and poor prognosis in colorectal cancer. 2015.03 Carcinogenesis 36 346-54 Metastasis-associated protein is a predictive biomarker for metastasis and recurrence in gastric cancer. 2016.10 Oncology reports 36 1893-900 Elevated serum concentration of monocyte chemotactic protein 4 (MCP-4) as a novel non-invasive prognostic and predictive biomarker for detection of metastasis in colorectal cancer. 2016.09 Journal of surgical oncology 114 483-9 FOXM1 and FOXQ1 Are Promising Prognostic Biomarkers and Novel Targets of Tumor-Suppressive miR-342 in Human Colorectal Cancer. 2016.10 Clinical cancer research : an official journal of the American Association for Cancer Research 22 4947-4957 Intravital imaging of the effects of 5-fluorouracil on the murine liver microenvironment using 2-photon laser scanning microscopy. 2016.04 Oncology letters 11 2433-2439 Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer. 2016.03 Oncotarget 7 16158-71 Microsatellite Alterations With Allelic Loss at 9p24.2 Signify Less-Aggressive Colorectal Cancer Metastasis. 2016.04 Gastroenterology 150 944-55 Emerging Role of MicroRNAs as Liquid Biopsy Biomarkers in Gastrointestinal Cancers. 2017.01 Clinical cancer research : an official journal of the American Association for Cancer Research Objective Predictive Score as a Feasible Biomarker for Short-term Survival in TerminalIy Ill Patients with Cancer. 2017.01 Anticancer research 37 267-275 Genome-Wide miRNA Analysis Identifies miR-188-3p as a Novel Prognostic Marker and Molecular Factor Involved in Colorectal Carcinogenesis. 2017.03 Clinical cancer research : an official journal of the American Association for Cancer Research 23 1323-1333 Exportin-5 Functions as an Oncogene and a Potential Therapeutic Target in Colorectal Cancer. 2017.03 Clinical cancer research : an official journal of the American Association for Cancer Research 23 1312-1322 Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer. 2017.01 Gut 66 107-117 Circulating microRNA-203 predicts prognosis and metastasis in human colorectal cancer. 2017.04 Gut 66 654-665 |
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