職名 教授
氏名 こんどう みねお
近藤 峰生
生年月 1965.11.24
所属 部局 医学系研究科
学科・専攻 生命医科学専攻
講座 臨床医学系講座
教育研究分野 眼科学
TEL 059-231-5027
FAX 059-231-3036
E-mail mineo@med.mie-u.ac.jp
個人のホームページ  
学歴 1991金沢大学医学部医学科卒業
1997名古屋大学大学院医学研究科 博士課程・博士後期課程 修了
学位 医学博士(1997)
所属学会 日本眼科学会(常務理事)
日本網膜硝子体学会(常務理事)
日本臨床視覚電気生理学会(理事長)
日本視野画像学会(理事)
日本神経眼科学会(評議員)
日本眼循環学会(理事)
日本小児眼科学会(理事)
Japan Macula Club(世話人)
International Society for Clinical Electrophysiology of Vision (Vice President)
Association for Research in Vision & Ophthalmology (Gold Fellow)
American Academy of Ophthalmology (Member)
Macula Society (Member)
Retina Society (Member)


社会活動 日本網膜色素変性症協会(学術理事)
独立行政法人 医薬品医療機器総合機構(PMDA)眼科専門委員


職歴 1991年:公立陶生病院 研修医 (1992年3月31日まで)
1992年:名古屋大学医学部附属病院 研修医(眼科学教室入局)(1993年3月31日まで)
1997年名古屋大学医学部研究生(眼科学講座)(1998年6月30日まで)
1998年:名古屋大学医学部附属病院眼科 助手
1999年:名古屋大学医学部附属病院眼科 助手休職
1999年:米国ミシガン大学眼科留学(Research Fellow, Prof. Paul A. Sieving )
2001年:米国ミシガン大学眼科留学より帰国
2001年:名古屋大学医学部附属病院眼科 助手復職
2002年:名古屋大学医学部附属病院眼科 講師
2006年:名古屋大学大学院医学系研究科 感覚器障害制御学(眼科) 准教授
2011年三重大学大学院医学系研究科 臨床医学系講座眼科学 教授
学術(芸術)賞 Pfizer Ophthalmic Award Japan,腫瘍関連網膜症に対する新規原因抗原の発見,日本眼科学会
日本眼科学会学術奨励賞,多局所ERGの明順応における増幅現象,2001.04,日本眼科学会
ロート賞,2002.05
ジャムコン賞,2004.12
日本眼科学会評議員会賞(JOS Council Award),2009.04
日本医師会医学研究助成受賞,2009.11,日本医師会
専門分野 眼科学
視覚科学
臨床視覚電気生理学
現在の研究課題 ・網膜硝子体疾患の病態解明
・網膜硝子体疾患の電気生理学的解析
・網膜硝子体疾患のイメージング
・網膜硝子体疾患の手術
・網膜疾患動物モデルの研究と新規治療法開発
担当科目 眼科診断学
主な業績等 Spondylometaphyseal dysplasia with cone-rod dystrophy. 2011.04 American journal of medical genetics. Part A 155A 845-9
Identification of autoantibodies against TRPM1 in patients with paraneoplastic retinopathy associated with ON bipolar cell dysfunction:TRPM1 antibody in paraneoplastic retinopathy 共著 2011.05 PLoS One
Changes in areas of capillary nonperfusion after intravitreal injection of bevacizumab in eyes with branch retinal vein occlusion. 2011.06 Retina (Philadelphia, Pa.) 31 1068-74
Rebound of macular edema after intravitreal bevacizumab therapy in eyes with macular edema secondary to branch retinal vein occlusion. 2011.06 Retina (Philadelphia, Pa.) 31 1075-82
Significant correlation between electroretinogram parameters and ocular vascular endothelial growth factor concentration in central retinal vein occlusion eyes. 2011.07 Investigative ophthalmology & visual science 52 5737-42
miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression. 2011.08 Nature neuroscience 14 1125-34
Enhancement of ON-bipolar cell responses of cone electroretinograms in rabbits with the Pro347Leu rhodopsin mutation. 2011.09 Investigative ophthalmology & visual science 52 7610-7
Real-time imaging of rabbit retina with retinal degeneration by using spectral-domain optical coherence tomography. 2012 PloS one 7 e36135-
Two novel mutations in the EYS gene are possible major causes of autosomal recessive retinitis pigmentosa in the Japanese population. 2012 PloS one 7 e31036-
Short-interfering RNAs induce retinal degeneration via TLR3 and IRF3. 2012.01 Molecular therapy : the journal of the American Society of Gene Therapy 20 101-8
ISCEV standard for clinical multifocal electroretinography (mfERG) (2011 edition). 2012.02 Documenta ophthalmologica. Advances in ophthalmology 124 1-13
Photoreceptor and post-photoreceptoral contributions to photopic ERG a-wave in rhodopsin P347L transgenic rabbits. 2012.03 Investigative ophthalmology & visual science 53 1467-72
Presynaptic dystroglycan-pikachurin complex regulates the proper synaptic connection between retinal photoreceptor and bipolar cells. 2012.05 The Journal of neuroscience : the official journal of the Society for Neuroscience 32 6126-37
Clinical features of a Japanese case with Bothnia dystrophy. 2012.06 Ophthalmic genetics 33 83-8
Focal macular electroretinograms after intravitreal injections of bevacizumab for age-related macular degeneration. 2012.06 Investigative ophthalmology & visual science 53 4185-90
Transcorneal electrical stimulation promotes survival of photoreceptors and improves retinal function in rhodopsin P347L transgenic rabbits. 2012.06 Investigative ophthalmology & visual science 53 4254-61
A perspective from magnetic resonance imaging findings of the inner ear: Relationships among cerebrospinal, ocular and inner ear fluids. 2012.08 Auris, nasus, larynx 39 345-55
Age-dependent alteration of intraocular soluble heparan sulfate levels and its implications for proliferative diabetic retinopathy. 2013 Molecular vision 19 1125-31
Degeneration of retinal on bipolar cells induced by serum including autoantibody against TRPM1 in mouse model of paraneoplastic retinopathy. 2013 PloS one 8 e81507-
Influence of preoperative intravitreal bevacizumab on visual function in eyes with proliferative diabetic retinopathy. 2013 Ophthalmic research 49 30-6
Peripheral capillary nonperfusion and full-field electroretinographic changes in eyes with frosted branch-like appearance retinal vasculitis. 2013 Clinical ophthalmology (Auckland, N.Z.) 7 137-40
Uniform suspension of the clustered triamcinolone acetonide particle. 2013 Journal of ophthalmology 2013 315658-
[Comparison between subtraction skin electrodes and corneal-contact electrodes in flash electroretinograms]. 2013.01 Nippon Ganka Gakkai zasshi 117 5-11
Cord blood transplantation combined with rituximab for Wiskott-Aldrich syndrome with autoimmune thrombotic thrombocytopenic purpura. 2013.07 The Journal of allergy and clinical immunology 132 226-7
Focal cone ERGs of rhodopsin Pro347Leu transgenic rabbits. 2013.10 Vision research 91 118-23
Functional endothelial progenitor cells selectively recruit neurovascular protective monocyte-derived F4/80(+) /Ly6c(+) macrophages in a mouse model of retinal degeneration. 2013.10 Stem cells (Dayton, Ohio) 31 2149-61
Whole genome sequencing in patients with retinitis pigmentosa reveals pathogenic DNA structural changes and NEK2 as a new disease gene. 2013.10 Proceedings of the National Academy of Sciences of the United States of America 110 16139-44
Relationship between retinal layer thickness and focal macular electroretinogram components after epiretinal membrane surgery. 2013.11 Investigative ophthalmology & visual science 54 7207-14
Bilateral retinal detachment in Werner syndrome. 2014 Retinal cases & brief reports 8 92-4
Changes in outer retinal microstructures during six month period in eyes with acute zonal occult outer retinopathy-complex. 2014 PloS one 9 e110592-
Choroidal atrophy in a patient with paraneoplastic retinopathy and anti-TRPM1 antibody. 2014 Clinical ophthalmology (Auckland, N.Z.) 8 369-73
Histopathological examination of Acanthamoeba sclerokeratitis. 2014 Clinical ophthalmology (Auckland, N.Z.) 8 251-3
Probing of congenital nasolacrimal duct obstruction with dacryoendoscope. 2014 Clinical ophthalmology (Auckland, N.Z.) 8 977-80
Whole exome analysis identifies frequent CNGA1 mutations in Japanese population with autosomal recessive retinitis pigmentosa. 2014 PloS one 9 e108721-
A long-term follow-up of patients with retinopathy of prematurity treated with photocoagulation and cryotherapy. 2014.02 Nagoya journal of medical science 76 121-8
Autoantibodies to transient receptor potential cation channel, subfamily M, member 1 in a Japanese patient with melanoma-associated retinopathy. 2014.03 Japanese journal of ophthalmology 58 166-71
Clinical phenotype in ten unrelated Japanese patients with mutations in the EYS gene. 2014.03 Ophthalmic genetics 35 25-34
Electroretinograms and level of aqueous vascular endothelial growth factor in eyes with hemicentral retinal vein occlusion or branch retinal vein occlusion. 2014.05 Japanese journal of ophthalmology 58 232-6
Transient increase of retinal nerve fiber layer thickness after macular hole surgery. 2014.06 International ophthalmology 34 575-81
Ultra-WideField fluorescein angiography by oral administration of fluorescein. 2014.08 Acta ophthalmologica 92 e417-8
The first USH2A mutation analysis of Japanese autosomal recessive retinitis pigmentosa patients: a totally different mutation profile with the lack of frequent mutations found in Caucasian patients. 2014.09 Journal of human genetics 59 521-8
A Naturally Occurring Canine Model of Autosomal Recessive Congenital Stationary Night Blindness. 2015 PloS one 10 e0137072-
Incidence of retinal detachment associated with atopic dermatitis in Japan: review of cases from 1992 to 2011. 2015 Clinical ophthalmology (Auckland, N.Z.) 9 1129-34
Pikachurin Protein Required for Increase of Cone Electroretinogram B-Wave during Light Adaptation. 2015 PloS one 10 e0128921-
Short Pulse Duration High-Power Laser Photocoagulation during Vitrectomy for Diabetic Retinopathy Reduces Postoperative Inflammation. 2015 PloS one 10 e0135126-
Significant Correlation between Retinal Venous Tortuosity and Aqueous Vascular Endothelial Growth Factor Concentration in Eyes with Central Retinal Vein Occlusion. 2015 PloS one 10 e0134267-
Changes in angle of optic nerve and angle of ocular orbit with increasing age in Japanese children. 2015.02 The British journal of ophthalmology 99 263-6
Clinical characteristics of congenital and developmental cataract undergoing surgical treatment. 2015.05 Japanese journal of ophthalmology 59 148-56
Effect of Pupil Size on Flicker ERGs Recorded With RETeval System: New Mydriasis-Free Full-Field ERG System. 2015.06 Investigative ophthalmology & visual science 56 3684-90
Electroretinographic assessment of rod- and cone-mediated bipolar cell pathways using flicker stimuli in mice. 2015.06 Scientific reports 5 10731-
A survey of the surgical treatment of congenital and developmental cataracts in Japan. 2015.07 Japanese journal of ophthalmology 59 203-8
Exposure of haptic of posterior chamber intraocular lens after sutureless intrascleral fixation. 2015.08 BMC ophthalmology 15 104-
Histopathologic findings of perforated corneas due to ferric ion infiltration. 2015.08 Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 50 322-7
In vivo imaging of axonal transport of mitochondria in the diseased and aged mammalian CNS. 2015.08 Proceedings of the National Academy of Sciences of the United States of America 112 10515-20
Functional and morphological study of retinal photoreceptor cell degeneration in transgenic rabbits with a Pro347Leu rhodopsin mutation. 2015.09 Japanese journal of ophthalmology 59 353-63
Mutation analysis of BEST1 in Japanese patients with Best's vitelliform macular dystrophy. 2015.11 The British journal of ophthalmology 99 1577-82
Pathologic Changes of Cone Photoreceptors in Eyes With Occult Macular Dystrophy. 2015.11 Investigative ophthalmology & visual science 56 7243-9
Hidden Genetic Variation in LCA9-Associated Congenital Blindness Explained by 5'UTR Mutations and Copy-Number Variations of NMNAT1. 2015.12 Human mutation 36 1188-96
Importance of Central Retinal Sensitivity for Prediction of Visual Acuity after Intravitreal Bevacizumb in Eyes with Macular Edema Associated with Branch Retinal Vein Occlusion. 2016 PloS one 11 e0149246-
Lecithin-Bound Iodine Prevents Disruption of Tight Junctions of Retinal Pigment Epithelial Cells under Hypoxic Stress. 2016 Journal of ophthalmology 2016 9292346-
Method of Quantifying Size of Retinal Hemorrhages in Eyes with Branch Retinal Vein Occlusion Using 14-Square Grid: Interrater and Intrarater Reliability. 2016 Journal of ophthalmology 2016 1960190-
Novel mutations in the COL2A1 gene in Japanese patients with Stickler syndrome. 2016 Human genome variation 3 16018-
A Case of Sustained Intraocular Pressure Elevation after Multiple Intravitreal Injection of Ranibizumab and Aflibercept for Neovascular Age-Related Macular Degeneration. 2016.01 Case reports in ophthalmology 7 230-6
Effect of topical rebamipide on conjunctival goblet cell recovery after vitrectomy. 2016.01 Scientific reports 6 19516-
Idiopathic Intracranial Hypertension in a Prepubertal Pediatric Japanese Patient Complicated by Severe Papilledema. 2016.01 Case reports in ophthalmology 7 148-53
Temporal Properties of Cone ERGs of Pikachurin Null Mutant Mouse. 2016.03 Investigative ophthalmology & visual science 57 1264-9
Surgical outcomes of congenital and developmental cataracts in Japan. 2016.05 Japanese journal of ophthalmology 60 127-34
[Guide for Clinical Use of Hydroxychloroquine]. 2016.06 Nippon Ganka Gakkai zasshi 120 419-28
[Intravitreal Triamcinolone Acetonide for Persistent Diabetic Macular Edema after Vitrectomy]. 2016.06 Nippon Ganka Gakkai zasshi 120 429-38
RPE65 Mutations in Two Japanese Families with Leber Congenital Amaurosis. 2016.06 Ophthalmic genetics 37 161-9
Electroretinographic effects of retinal dragging and retinal folds in eyes with familial exudative vitreoretinopathy. 2016.07 Scientific reports 6 30523-
Cytoprotective Effects of a Novel Nrf2 Activator, RS9, in Rhodopsin Pro347Leu Rabbits. 2016.08 Current eye research 41 1123-1126
Evaluation of micro Electroretinograms Recorded with Multiple Electrode Array to Assess Focal Retinal Function. 2016.08 Scientific reports 6 30719-
Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration. 2016.08 Scientific reports 6 31184-
Mテシller cell metabolic chaos during retinal degeneration. 2016.09 Experimental eye research 150 62-70
Novel RP1L1 Variants and Genotype-Photoreceptor Microstructural Phenotype Associations in Cohort of Japanese Patients With Occult Macular Dystrophy. 2016.09 Investigative ophthalmology & visual science 57 4837-46
Screening for diabetic retinopathy using new mydriasis-free, full-field flicker ERG recording device. 2016.11 Scientific reports 6 36591-
Histopathological Changes of Inner Retina, Optic Disc, and Optic Nerve in Rabbit with Advanced Retinitis Pigmentosa. 2016.12 Neuro-ophthalmology (Aeolus Press) 40 286-291
Long-Term Protection of Genetically Ablated Rabbit Retinal Degeneration by Sustained Transscleral Unoprostone Delivery. 2016.12 Investigative ophthalmology & visual science 57 6527-6538
Inherited Retinal Degeneration: Genetics, Disease Characterization, and Outcome Measures. 2017 Journal of ophthalmology 2017 2109014-
Oxidative Stress in Retinal Diseases. 2017 Oxidative medicine and cellular longevity 2017 4076518-
A pharmacological approach in newly established retinal vein occlusion model. 2017.03 Scientific reports 7 43509-
Contributions of Second- and Third-Order Retinal Neurons to Cone Electroretinograms After Loss of Rod Function in Rhodopsin P347L Transgenic Rabbits. 2017.03 Investigative ophthalmology & visual science 58 1417-1424
A novel method to reduce noise in electroretinography using skin electrodes: a study of noise level, inter-session variability, and reproducibility. 2017.04 International ophthalmology 37 317-324
Two year result of intravitreal bevacizumab for diabetic macular edema using treat and extend protocol. 2017.04 Medicine 96 e6406-
Annual incidences of visual impairment during 10-year period in Mie prefecture, Japan. 2017.07 Japanese journal of ophthalmology 61 293-298
Effect of intravitreal ranibizumab on the ocular circulation of the untreated fellow eye. 2017.08 Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Oph 255 1543-1550
Conjunctival Goblet Cell Density Following Cataract Surgery With Diclofenac Versus Diclofenac and Rebamipide: A Randomized Trial. 2017.09 American journal of ophthalmology 181 26-36
Electrophysiological responses from intrinsically photosensitive retinal ganglion cells are diminished in glaucoma patients. 2017.10 Journal of optometry 10 226-232
Factors Affecting Mydriasis-Free Flicker ERGs Recorded With Real-Time Correction for Retinal Illuminance: Study of 150 Young Healthy Subjects. 2017.10 Investigative ophthalmology & visual science 58 5280-5286
New photic stimulating system with white light-emitting diodes to elicit electroretinograms from zebrafish larvae. 2017.10 Documenta ophthalmologica. Advances in ophthalmology 135 147-154
Temporal Properties of Flicker ERGs in Rabbit Model of Retinitis Pigmentosa. 2017.10 Investigative ophthalmology & visual science 58 5518-5525
Unilateral cancer-associated retinopathy: diagnosis, serology and treatment. 2017.12 Documenta ophthalmologica. Advances in ophthalmology 135 233-240
Short-Term Results of Intravitreal Triamcinolone Acetonide Combined with Cataract Surgery for Diabetic Macular Edema in Japan: In the Era of Anti-Vascular Endothelial Growth Factor Therapy. 2018 Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 240 73-80
Diffusion tensor imaging and magnetic resonance spectroscopy in a patient with adult onset tuberous sclerosis complex. 2018.02 Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 48 108-110