| 教員紹介トップページへ | 三重大学トップページへ |
| 職名 | 准教授 | |||||||||
| 氏名 | かわもと えいじ 川本 英嗣 |
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| 生年月 | 1976 | |||||||||
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| a-2@umin.org | ||||||||||
| 個人のホームページ | http://mie-eccc.com/?page_id=24 | |||||||||
| 学歴 | 富山医科薬科大学 学士課程 (1998年04月01日～2004年03月31日) 卒業・修了
三重大学大学院医学系研究科 分子病態学 博士課程・博士後期課程 (2013年04月01日～2017年03月31日) 卒業・修了 |
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| 学位 | 2017.03 医学博士 三重大学大学院医学系研究科 分子病態学
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| 所属学会 | 日本救急医学会 日本麻酔科学会 日本臨床救急医学会 日本集中治療学会 日本医学シミュレーション学会 日本shock学会 日本臨床麻酔学会 | |||||||||
| 社会活動 | ||||||||||
| 職歴 | 2004.04～2006.03 中部労災病院 初期臨床研修医 研修医
2006.04～2009.06 中労災病院 麻酔科 医員 2009.07～2012.03 聖マリアンナ医科大学 救急医学 助教 2012.04～ 三重大学医学部附属病院 救命救急センター 助教 |
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| 学術（芸術）賞 | 第32回日本shock学会総会 会長賞受賞,敗血症患者の細胞外小胞にはインテグリン，PD-L1，PD-L2が発現する,2017.09,日本shock学会
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| 専門分野 | 救急医学（日本救急医学会 指導医）
麻酔科学（日本麻酔科学会 指導医） 集中治療医学（日本集中治療医学会 専門医） シミュレーション教育 |
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| 現在の研究課題 | PCAS病態治療におけるデザイナーエキソソームの革新的応用 | |||||||||
| 担当科目 | 畳み込みニューラルネットワーク（CNN）を活用した肺炎の診断方法の開発 | |||||||||
| 主な業績等 | [Case of obstructive sleep apnea possibly having led to postoperative appearance of generalized convulsion]. 共著 2010.04 Masui. The Japanese journal of anesthesiology 59 507-10
[Anesthetic considerations for spine surgery in 71 patients with infectious spondylitis: effects of different pathogen either pyogenic or tuberculous on intraoperative blood loss]. 共著 2010.06 Masui. The Japanese journal of anesthesiology 59 711-4 [A case-control study of airway management for 68 patients with cervical spine injury: comparison of the direct laryngoscope with a Macintosh blade and the fiberoptic bronchoscope]. 共著 2010.08 Masui. The Japanese journal of anesthesiology 59 976-80 Anti-integrin therapy for multiple sclerosis. 共著 2012 Autoimmune diseases 2012 357101- 一般病棟でのDAM(Difficult Airway Management) 共著 2012.01 日本臨床麻酔学会誌 32 117-120 Positive clinical risk factors predict a high rate of methicillin-resistant Staphylococcus aureus colonization in emergency department patients. 共著 2012.12 American journal of infection control 40 988-91 インテグリンと炎症 共著 2013 Coagulation and Inflammation 7 医師を動かすドクターコール 全身症状のアセスメントとドクターコール 単著 2013.06 救急看護・トリアージ 7-13 救急事例で学ぶSBAR活用のポイント 意識障害・外傷編 単著 2013.08 救急看護・トリアージ 16-22 気管挿管 共著 2014 救急医学 38 888-892 高体温症に対する冷却 共著 2014 救急医学 38 718-722 Endothelial connexin32 enhances angiogenesis by positively regulating tube formation and cell migration. 共著 2014.02 Experimental cell research 321 133-41 トロンボモジュリン (TM) は白血球インテグリンと結合する : TM抗炎症作用機序への関与の可能性 共著 2015 Shock 30 44-53 Saving a life- the effect of the medical emergency team in preventing the deterioration of inpatients 共著 2015.06 Journal of Medical Safety 67-75 手術室における火災対応 共著 2016.04 日本火災学会誌 66 2-7 LFA-1 and Mac-1 integrins bind to the serine/threonine-rich domain of thrombomodulin. 共著 2016.05 Biochemical and biophysical research communications 473 1005-12 Gap junction-mediated regulation of endothelial cellular stiffness. 共著 2017.07 Scientific Report 7(1) 6134- Gap junction-mediated regulation of endothelial cellular stiffness. 共著 2017.07 Scientific reports 7 6134- Two cases of life-threatening arrhythmia induced by risperidone: evaluation of risperidone and 9-hydroxy-risperidone concentrations. 共著 2017.07 Acute medicine & surgery 4 341-343 Study protocol for the G-SPIRIT trial: a randomised, placebo-controlled, double-blinded phase III trial of granulocyte colony-stimulating factor-mediated neuroprotection for acute spinal cord injury. 2018.05 BMJ open 8 e019083- Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor ﾎｳ expression. 2018.06 Experimental cell research 367 264-273 Biomechanical profiles of tracheal intubation: a mannequin-based study to make an objective assessment of clinical skills by expert anesthesiologists and novice residents. 2018.12 BMC medical education 18 293- Exosomes in Sepsis and Inflammatory Tissue Injury. 2019 Current pharmaceutical design 25 4486-4495 Connexins and Integrins in Exosomes. 2019.01 Cancers 11 Exosomal regulation of lymphocyte homing to the gut. 2019.01 Blood advances 3 1-11 Anti-adhesive effects of human soluble thrombomodulin and its domains. 2019.04 Biochemical and biophysical research communications 511 312-317 Talin-2 regulates integrin functions in exosomes. 2019.05 Biochemical and biophysical research communications 512 429-434 Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis. 2019.07 Biomedicines 7 Integrin and PD-1 Ligand Expression on Circulating Extracellular Vesicles in Systemic Inflammatory Response Syndrome and Sepsis. 2019.07 Shock (Augusta, Ga.) 52 13-22 How ICU Patient Severity Affects Communicative Interactions Between Healthcare Professionals: A Study Utilizing Wearable Sociometric Badges. 2020 Frontiers in medicine 7 606987- How ICU Patient Severity Affects Communicative Interactions Between Healthcare Professionals: A Study Utilizing Wearable Sociometric Badges. 共著 2020 Frontiers in medicine 7 606987- Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin. 2020 Frontiers in cell and developmental biology 8 588066- Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin. 共著 2020 Frontiers in cell and developmental biology 8 588066- Feasibility of Measuring Face-to-Face Interactions among ICU Healthcare Professionals Using Wearable Sociometric Badges. 2020.01 American journal of respiratory and critical care medicine 201 245-247 Targeted remodeling of breast cancer and immune cell homing niches by exosomal integrins. 共著 2020.04 Diagnostic pathology 15 38- Virtual reality as a non-pharmacologic analgesic for fasciotomy wound infections in acute compartment syndrome: a case report. 共著 2020.04 Journal of medical case reports 14 46- Recombinant Human Soluble Thrombomodulin Suppresses Monocyte Adhesion by Reducing Lipopolysaccharide-Induced Endothelial Cellular Stiffening. 共著 2020.07 Cells 9 Acquired factor XIII deficiency in two patients with bleeding events during veno-venous extracorporeal membrane oxygenation treatment. 2020.09 Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 23 283-287 Acquired factor XIII deficiency in two patients with bleeding events during veno-venous extracorporeal membrane oxygenation treatment. 共著 2020.09 Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 23 283-287 The Role of Innate Lymphoid Cells in the Regulation of Immune Homeostasis in Sepsis-Mediated Lung Inflammation. 共著 2020.10 Diagnostics (Basel, Switzerland) 10 Intestinal Epithelium-Derived Luminally Released Extracellular Vesicles in Sepsis Exhibit the Ability to Suppress TNF-a and IL-17A Expression in Mucosal Inflammation. 共著 2020.11 International journal of molecular sciences 21 Social Network Analysis of Intensive Care Unit Health Care Professionals Measured by Wearable Sociometric Badges: Longitudinal Observational Study. 共著 2020.12 Journal of medical Internet research 22 e23184- Methods to Study Integrin Functions on Exosomes. 共著 2021 Methods in molecular biology (Clifton, N.J.) 2217 265-281 Potential Roles of Muscle-Derived Extracellular Vesicles in Remodeling Cellular Microenvironment: Proposed Implications of the Exercise-Induced Myokine, Irisin. 共著 2021 Frontiers in cell and developmental biology 9 634853- Remodeling of Bone Marrow Niches and Roles of Exosomes in Leukemia. 共著 2021.02 International journal of molecular sciences 22 The Lectin-Like Domain of Thrombomodulin Inhibits ﾎｲ1 Integrin-Dependent Binding of Human Breast Cancer-Derived Cell Lines to Fibronectin. 共著 2021.02 Biomedicines 9 Internet-Based Individualized Cognitive Behavioral Therapy for Shift Work Sleep Disorder Empowered by Well-Being Prediction: Protocol for a Pilot Study. 共著 2021.03 JMIR research protocols 10 e24799- Sepsis Induces Deregulation of IL-13 Production and PD-1 Expression in Lung Group 2 Innate Lymphoid Cells. 共著 2021.03 Shock (Augusta, Ga.) 55 357-370 Veno-arterial extracorporeal membrane oxygenation and targeted temperature management in tricyclic antidepressant-induced cardiac arrest: A case report and literature review. 共著 2021.03 Medicine 100 e24980- Randomized trial of granulocyte colony-stimulating factor for spinal cord injury. 共著 2021.04 Brain : a journal of neurology 144 789-799 The characteristics, types of intervention, and outcomes of postoperative patients who required rapid response system intervention: a nationwide database analysis. 共著 2021.04 Journal of anesthesia 35 222-231 The Spike Glycoprotein of SARS-CoV-2 Binds to ﾎｲ1 Integrins Expressed on the Surface of Lung Epithelial Cells. 共著 2021.04 Viruses 13 Irisin supports integrin-mediated cell adhesion of lymphocytes. 共著 2021.07 Biochemistry and biophysics reports 26 100977- Ligand-competent fractalkine receptor is expressed on exosomes. 共著 2021.07 Biochemistry and biophysics reports 26 100932- Sociometric wearable devices for studying human behavior in corporate and healthcare workplaces. 共著 2021.07 BioTechniques 71 392-399 Cellular and Exosomal Regulations of Sepsis-Induced Metabolic Alterations. 共著 2021.08 International journal of molecular sciences 22 Cytoskeletal Actin Structure in Osteosarcoma Cells Determines Metastatic Phenotype via Regulating Cell Stiffness, Migration, and Transmigration. 2021.09 Current issues in molecular biology 43 1255-1266 Elevated Plasma Soluble PD-L1 Levels in Out-of-Hospital Cardiac Arrest Patients. 共著 2021.09 Journal of clinical medicine 10 Endothelial connexin-integrin crosstalk in vascular inflammation. 共著 2021.09 Biochimica et biophysica acta. Molecular basis of disease 1867 166168- miRNA-200c-3p targets talin-1 to regulate integrin-mediated cell adhesion. 共著 2021.11 Scientific reports 11 21597- Recombinant soluble thrombomodulin accelerates epithelial stem cell proliferation in mouse intestinal organoids and promotes the mucosal healing in colitis. 共著 2021.11 Journal of gastroenterology and hepatology 36 3149-3157 Substrate stiffness modulates endothelial cell function via the YAP-Dll4-Notch1 pathway. 共著 2021.11 Experimental cell research 408 112835- miR-200c-3pによるインテグリンを介した細胞接着と焦点接着斑形成の制御(Integrin-mediated cell adhesion and focal adhesion formation are regulated by miR-200c-3p) 共著 2022.05 日本血栓止血学会誌 33巻2号 244-244 Possible Metastatic Stage-Dependent ILC2 Activation Induces Differential Functions of MDSCs through IL-13/IL-13Rα1 Signaling during the Progression of Breast Cancer Lung Metastasis. 共著 2022.07 Cancers 14巻13号 Sequential organ failure assessment score as a predictor of the outcomes of patients hospitalized for classical or exertional heatstroke. 共著 2022.09 Scientific reports 12巻1号 16373-16373 Conservative medical management combined with follow-up multidetector computed tomography of tracheobronchial injury caused by penetrating injuries: A case report. 共著 2022.12 Trauma case reports 42巻 100710-100710 Tetraploidy-linked sensitization to CENP-E inhibition in human cells. 共著 2023.01 Molecular oncology MicroRNA Profiles in Intestinal Epithelial Cells in a Mouse Model of Sepsis. 共著 2023.02 Cells 12巻5号 A Novel Approach to Reducing Lung Metastasis in Osteosarcoma: Increasing Cell Stiffness with Carbenoxolone. 共著 2023.05 Current issues in molecular biology 45巻5号 4375-4388 Effect of an Internet-Delivered Cognitive Behavioral Therapy-Based Sleep Improvement App for Shift Workers at High Risk of Sleep Disorder: Single-Arm, Nonrandomized Trial. 共著 2023.08 Journal of medical Internet research 25巻 e45834- Correlation Between Social Network Structure and Well-being of Healthcare Workers in Intensive Care Units: A Prospective Observational Study. 共著 2023.11 Interactive journal of medical research 12巻 e50148- 救急・集中治療分野における交代勤務医療従事者のフィットネストラッカーとアンケートから分かる離職者の傾向 共著 2023.12 日本救急医学会雑誌 34巻12号 742-742 miR-200c-3p regulates ﾎｱ4 integrin-mediated T cell adhesion and migration. 2024.07 Experimental cell research 440 114146- Irisin promotes intestinal epithelial cell proliferation via Wnt/ﾎｲ-catenin and focal adhesion kinase signaling pathways. 2024.10 Scientific reports 14 25702- Roles of programmed death-1 and muscle innate lymphoid cell-derived interleukin 13 in sepsis-induced intensive care unit-acquired weakness. 2024.10 Journal of cachexia, sarcopenia and muscle 15 1999-2012 Virtual Reality-Applied Home-Visit Rehabilitation for Patients With Chronic Pain: Protocol for Single-Arm Pre-Post Comparison Study. 2024.12 JMIR research protocols 13 e58734- Machine Learning-Based Prediction of Delirium and Risk Factor Identification in ICU Patients with Burns: A Retrospective Observational Study. 2025.02 JMIR formative research RRS院内急変対応システム 共著 2012.07 メディカルサイエンスインターナショナル FCCSプロバイダーマニュアル 第2版 共著 2013.10 メディカルサイエンスインターナショナル SimWars 救急シミュレーションシナリオ集 共著 2017.07 メディカルサイエンスインターナショナル |
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