三重大学教員紹介

職名

講師

氏名

ふじもと　なおき
藤本　直紀

生年月

所属	部局	医学系研究科
	学科・専攻	生命医科学専攻
	講座	臨床医学系講座
	教育研究分野

TEL

FAX

E-mail

naokifujimo@med. (末尾に mie-u.ac.jp を補ってください)

個人のホームページ

学歴

学位

博士（医学）

所属学会

社会活動

職歴

学術（芸術）賞

専門分野

循環器内科、運動生理学、心機能

現在の研究課題

・心不全患者における心機能、血行動態の評価
・心不全患者や健常高齢者における運動療法

担当科目

主な業績等

Publications
1. Moriwaki K, Fujimoto N, Omori T, Miyahara S, Kameda I, Ishiyama M, Sugiura E, Nakamori S, Dohi K. Comparison of haemodynamic response to muscle reflex in heart failure with reduced vs. preserved ejection fraction. ESC Heart Fail. 2021. doi: 10.1002/ehf2.13682.

2. Ishiura J, Nakamori S, Ishida M, Imanaka-Yoshida K, Hiroe M, Moriwaki K, Sugiura E, Fujimoto N, Takafuji M, Ichikawa Y, Kitagawa K, Sakuma H, Dohi K. Serial Native T1 Assessment for LV Functional Recovery in Recent-Onset DCM: A Comparison with Histology. JACC Cardiovasc Imaging. 2021:S1936-878X(21)00633-1.

3. Sakaguchi S, Fujimoto N, Ichikawa K, Izumi D, Katsuta K, Takafuji M, Imanaka-Yoshida K, Dohi K. Myopericarditis After COVID-19 mRNA Vaccination. Circ J. 2021. doi:10.1253/circj.CJ-21-0683.

4. Ishiyama M, Sugiura E, Ito H, Nakajima H, Kurita T, Fujimoto N, Dohi K. Refractory exercise-induced severe mitral regurgitation in a patient with hypertrophic cardiomyopathy. J Echocardiogr. 2021. doi:10.1007/s12574-021-00535-8.

5. Ishiyama M, Kurita T, Nakamura S, Omori T, Nakamori S, Ishida M, Fujimoto N, Kitagawa K, Sakuma H, Ito M, Dohi K. Prognostic importance of acute phase extracellular volume evaluated by cardiac magnetic resonance imaging for patients with acute myocardial infarction. Int J Cardiovasc Imaging. 2021. doi: 10.1007/s10554-021-02321-0.

6. Akatsuka T, Fujimoto N, Ishiyama M, Nakamori S, Imanaka-Yoshida K, Dohi K. Trajectory of left ventricular geometry and diastolic dysfunction in hereditary transthyretin cardiac amyloidosis. ESC Heart Fail. 2021. doi: 10.1002/ehf2.13454.

7. Kakuta K, Dohi K, Yamamoto T, Fujimoto N, Shimoyama T, Umegae S, Ito M. Coronary Microvascular Dysfunction Restored After Surgery in Inflammatory Bowel Disease: A Prospective Observational Study. J Am Heart Assoc. 2021;10:e019125.

8. Murakami H, Fujimoto N, Moriwaki K, Nakata K, Ishida M, Okamoto R, Ito M, Dohi K. Serial cardiac magnetic resonance imaging in wet beriberi. J Cardiol Cases. 2020;22:100-102.

9. Omori T, Nakamori S, Fujimoto N, Ishida M, Kitagawa K, Ichikawa Y, Kumagai N, Kurita T, Imanaka-Yoshida K, Hiroe M, Sakuma H, Ito M, Dohi K. Myocardial native T1 predicts load-independent left ventricular chamber stiffness in patients with HFpEF. JACC Cardiovasc Imaging. 2020;13(10):2117-2128.

10. Fukuma T, Fujimoto N, Ishiyama M, Dohi K. Atrial wall thickening, fevers, and atrial fibrillation caused by immunoglobulin G4-related biatrial cardiomyopathy. Eur Heart J. 2020;41:3488.

11. Carrick-Ranson G, Sloane NM, Howden EJ, Bhella PS, Sarma S, Shibata S, Fujimoto N, Hastings JL, Levine BD. The effect of lifelong endurance exercise on cardiovascular structure and exercise function in women. J Physiol. 2020;598:2589-605.

12. Fukuoka S, Dohi K, Takeuchi T, Moriwaki K, Ishiyama M, Omori T, Fujimoto N, Ito M. Mechanisms and prediction of short-term natriuretic effect of sodium-glucose cotransporter 2 inhibitor in heart failure patients coexisting type 2 diabetes mellitus. Heart Vessels. 2020;35:1218-26.

13. Ishiyama M, Kurita T, Ishiura J, Yamamoto N, Sugiura E, Ito H, Tada N, Fujimoto N, Ito M, Dohi K. Successful percutaneous treatment of recurrent post-infarction ventricular septal rupture using an Amplatzer duct occluder. J Cardiol Cases. 2019;21:12-15.

14. Fukuoka S, Kurita T, Takasaki A, Nakata T, Fujimoto N, Masuda J, Hoshino K, Tanigawa T, Koyabu S, Ito M, Dohi K. Clinical usefulness of instantaneous　wave-free ratio for the evaluation of coronary artery lesion with prior myocardial infarction: A multi-center study. Int J Cardiol Heart Vasc. 2019;26:100431.

15. Fujimoto N, Moriwaki K, Takeuchi T, Sawai T, Sato Y, Kumagai N, Masuda J, Nakamori S, Ito M, Dohi K. Effects of sitagliptin on exercise capacity and hemodynamics in patients with type 2 diabetes mellitus and coronary artery disease. Heart Vessels. 2020;35:605-613.

16. Mizutani H, Ogihara Y, Fujimoto N, Izumi D, Ohashi H, Mitani Y, Ito M, Dohi K. Pulmonary Perfusion Scintigraphy- Non-Invasive Method to Confirm Platypnea-Orthodeoxia Syndrome Treatment Effectiveness. Circ J. 2019;83:2570

17. Ogihara Y, Fujimoto N, Ohashi H, Yamamoto N, Ito H, Mitani Y, Aoki Y, Imanaka-Yosida K, Ito M, Dohi K. Case of Noonan Syndrome With an Expanding Coronary Arterial Aneurysm. Circ Cardiovasc Imaging. 2019;12:e009429.

18. Fujimoto N, Sato T, Moriwaki K, Sugiura E, Nakamori S, Imanaka-Yoshida K, Ito M, Dohi K. Early Localized Ventricular Septal Aneurysm Formation in Acute Eosinophilic Myocarditis. Circ J. 2019;83:2567.

19. Carrick-Ranson G, Spinale FG, Bhella PS, Sarma S, Shibata S, Fujimoto N, Hastings JL, Levine BD. Plasma matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs and aging and lifelong exercise adaptations in ventricular and arterial stiffness. Exp Gerontol. 2019;123:36-44.

20. Fukuoka S, Fujimoto N, Dohi K, Onuma H, Okamoto R, Kakimoto H, Ito M. Echocardiographic changes in diastolic filling and stroke volume during postural alterations and ankle exercise in a patient with congenital defect of the pericardium. J Echocardiogr. 2020;18:130-1.

21. Hieda M, Howden E, Shibata S, Fujimoto N, Bhella PS, Hastings JL, Tarumi T, Sarma S, Fu Q, Zhang R, Levine BD. Impact of Lifelong Exercise Training Dose on Ventricular-Arterial Coupling. Circulation. 2018;138:2638-47.

22. Okamoto R, Taniguchi M, Onishi Y, Kumagai N, Uraki J, Fujimoto N, Fujii E, Yano Y, Ogura T, Ito M. Predictors of confirmatory test results for the diagnosis of primary hyperaldosteronism in hypertensive patients with an aldosterone-to-renin ratio greater than 20. The SHRIMP study. Hypertens Res. 2019;42:40-51.

23. Shibata S, Fujimoto N, Hastings JL, Carrick-Ranson G, Bhella PS, Hearon C, Levine BD. The effect of lifelong exercise frequency on arterial stiffness. J Physiol. 2018;596:2783-2795.

24. Moriwaki K, Takeuchi T, Fujimoto N, Sawai T, Sato Y, Kumagai N, Masuda J, Nakamori S, Ishida M, Yamada N, Nakamura M, Sakuma H, Ito M, Dohi K. Effect of Sitagliptin on Coronary Flow Reserve Assessed by Magnetic Resonance Imaging in Type 2 Diabetic Patients With Coronary Artery Disease. Circ J. 2018;596:2783-2795.

25. Ito T, Fujimoto N, Ishikawa E, Dohi K, Fujimoto M, Murata T, Kiyohara M, Takeuchi H, Koyabu S, Nishimura H, Takeuchi T, Ito M. The effect of an L/N-type calcium channel blocker on intradialytic blood pressure in intradialytic hypertensive patients. Clin Exp Hypertens. 2019;41:92-99.

26. Katayama H, Matsumoto T, Wada H, Fujimoto N, Toyoda J, Abe Y, Ohishi K, Yamashita Y, Ikejiri M, Habe K, Katayama N. An Evaluation of Hemostatic Abnormalities in Patients With Hemophilia According to the Activated Partial Thromboplastin Time Waveform. Clin Appl Thromb Hemost. 2018;24:1170-1176.

27. Hieda M, Parker J, Rajabi T, Fujimoto N, Bhella PS, Prasad A, Hastings JL, Sarma S, Levine BD. Left Ventricular Volume-Time Relation in Patients With Heart Failure With Preserved Ejection Fraction. Am J Cardiol. 2018;121:609-614.

28. Miyahara S, Fujimoto N, Dohi K, Sugiura E, Moriwaki K, Omori T, Takeuchi T, Kumagai N, Nakamori S, Yamada N, Ito M. Postdischarge Light-Intensity Physical Activity Predicts Rehospitalization of Older Japanese Patients With Heart Failure. J Cardiopulm Rehabil Prev. 2018;38:182-186.

29. Kakuta K, Dohi K, Fujimoto N, Yamanaka T, Kawamura M, Ito M. Assessment of coronary artery disease based on coronary flow velocity reserve by transthoracic Doppler echocardiography and coronary computed tomography angiography in a patient with dextrocardia: a case report. J Echocardiogr. 2017. doi:10.1007/s12574-017-0367-z.

30. Howden EJ, Carrick-Ranson G, Sarma S, Hieda M, Fujimoto N, Levine BD. Effects of Sedentary Aging and Lifelong Exercise on Left Ventricular Systolic Function. Med Sci Sports Exerc. 2018;50:494-50.

31. Ikejiri M, Wada H, Tone S, Wakabayashi H, Hasegawa M, Matsumoto T, Fujimoto N, Yamada N, Ito M, Nakatani K, Sudo A. Comparison of three different anti-Xa assays in major orthopedic surgery patients treated with direct oral anticoagulant. Thromb J. 2017;15:27.

32. Kumagai N, Dohi K, Fujimoto N, Tanimura M, Sato Y, Miyahara S, Nakamori S, Fujii E, Yamada N, Ito M. A novel method for the quantitative evaluation of diurnal respiratory instability in patients with heart failure: A pilot study. J Cardiol. 2018;71:159-167.

33. Omori T, Kurita T, Dohi K, Takasaki A, Nakata T, Nakamori S, Fujimoto N, Kitagawa K, Hoshino K, Tanigawa T, Sakuma H, Ito M. Prognostic impact of unrecognized myocardial scar in the non-culprit territories by cardiac magnetic resonance imaging in patients with acute myocardial infarction. Eur Heart J Cardiovasc Imaging. 2018;19:108-116.

34. Matsumoto T, Wada H, Fujimoto N, Toyoda J, Abe Y, Ohishi K, Yamashita Y, Ikejiri M, Hasegawa K, Suzuki K, Imai H, Nakatani K, Katayama N. An Evaluation of the Activated Partial Thromboplastin Time Waveform. Clin Appl Thromb Hemost. 2017:1076029617724230. doi: 10.1177/1076029617724230.

35. Sawai T, Dohi K, Fujimoto N, Okubo S, Isaka N, Ichikawa T, Makino K, Okamoto S, Koyabu S, Kitamura T, Ogura T, Yamada T, Tamaru S, Nishikawa M, Nakamura M, Ito M; OWASE Study Investigators. Antialbuminuric effect of eplerenone in comparison to thiazide diuretics in patients with hypertension. J Clin Hypertens (Greenwich). 2017;19:990-998.

36. Okada Y, Shibata S, Fujimoto N, Best SA, Levine BD, Fu Q. Long-term effects　of a renin inhibitor versus a thiazide diuretic on arterial stiffness and left　ventricular diastolic function in elderly hypertensive patients. Am J Physiol Integul Integr Comp Physiol. 2017;313:R400-R409.

37. Tanimura M, Dohi K, Fujimoto N, Moriwaki K, Omori T, Sato Y, Sugiura E,　Kumagai N, Nakamori S, Kurita T, Fujii E, Yamada N, Ito M. Effect of Anemia on　Cardiovascular Hemodynamics, Therapeutic Strategy and Clinical Outcomes in Patients With Heart Failure and Hemodynamic Congestion. Circ J. 2017;81:1670-1677.

38. Nakamori S, Dohi K, Ishida M, Goto Y, Imanaka-Yoshida K, Omori T, Goto I, Kumagai N, Fujimoto N, Ichikawa Y, Kitagawa K, Yamada N, Sakuma H, Ito M. Native T1 Mapping and Extracellular Volume Mapping for the Assessment of Diffuse Myocardial Fibrosis in Dilated Cardiomyopathy. JACC Cardiovasc Imaging. JACC Cardiovasc Imaging. 2018;11:48-59.

39. Hasegawa M, Wada H, Yamaguchi T, Wakabayashi H, Fujimoto N, Matsumoto T, Hasegawa K, Yamada N, Ito M, Yamashita Y, Katayama N, Nakatani K, Sudo A. The Evaluation of D-Dimer Levels for the Comparison of Fibrinogen and Fibrin Units Using Different D-Dimer Kits to Diagnose VTE. Clin Appl Thromb Hemost. 2018;24:655-662.

40. Abdullah SM, Barkley KW, Bhella PS, Hastings JL, Matulevicius S, Fujimoto N, Shibata S, Carrick-Ranson G, Palmer MD, Gandhi N, DeFina LF, Levine BD. Lifelong Physical Activity Regardless of Dose Is Not Associated With Myocardial Fibrosis. Circ Cardiovasc Imaging. 2016 Nov;9(11).

41. Ikejiri M, Wada H, Yamada N, Nakamura M, Fujimoto N, Nakatani K, Matsuda A, Ogihara Y, Matsumoto T, Kamimoto Y, Ikeda T, Katayama N, Ito M. High prevalence of congenital thrombophilia in patients with pregnancy-related or idiopathic venous thromboembolism/ pulmonary embolism. Int J Hematol 2017;105:272-279.

42. Aota T, Wada H, Fujimoto N, Yamashita Y, Matsumoto T, Ohishi K, Suzuki K, Imai H, Usui M, Isaji S, Uchiyama T, Seki Y, Katayama N. Evaluation of the Diagnostic Criteria for the Basic Type of DIC Established by the Japanese Society of Thrombosis and Hemostasis. Clin Appl Thromb Hemost 2016;Oct 11.

43. Aota T, Wada H, Fujimoto N, Sugimoto K, Yamashita Y, Matsumoto T, Ohishi K, Suzuki K, Imai H, Kawasugi K, Madoiwa S, Asakura H, Katayama N. The valuable diagnosis of DIC and pre-DIC and prediction of a poor outcome by the evaluation of diagnostic criteria for DIC in patients with hematopoietic injury established by the Japanese Society of Thrombosis and Hemostasis. Thromb Res. 2016;147:80-84.

44. Carrick-Ranson G, Fujimoto N, Shafer KM, Hastings JL, Shibata S, Palmer MD, Boyd K, Levine BD. The effect of 1 year of Alagebrium and moderate-intensity exercise training on left ventricular function during exercise in seniors: a randomized controlled trial. J Appl Physiol (1985). 2016;121:528-36.

45. Takeuchi T, Fujimoto N, Dohi K, Ino K, Monma F, Katayama N, Ito M. Acute pulmonary edema with new giant V wave immediately after pericardiocentesis. Int J Cardiol. 2016;212:253-254..

46. Sato Y, Dohi K, Watanabe K, Tanimura M, Takeuchi T, Sugiura E, Sugimoto T, Kumagai N, Ogura T, Nakamori S, Fujimoto N, Yamada N, Ito M. Combination of Urinary Sodium/Creatinine Ratio and Plasma Brain Natriuretic Peptide Level Predicts Successful Tolvaptan Therapy in Patients With Heart Failure and Volume Overload. Int Heart J. 2016;57:211-9.

47. Ikejiri M, Wada H, Yamaguchi T, Miyazaki S, Hasegawa M, Wakabayashi H, Asanuma K, Sakaguchi A, Matsumoto T, Onishi K, Fujimoto N, Yamada N, Ito M, Katayama N, Sudo A. Comparison of three different anti-Xa assays in major orthopedic surgery patients treated with fondaparinux. Int J Hematol. 2016;103:554-9.

48. Yamaguchi T, Wada H, Miyazaki S, Hasegawa M, Wakabayashi H, Asanuma K, Fujimoto N, Matsumoto T, Ohishi K, Sakaguchi A, Yamada N, Ito M, Yamashita Y, Katayama N, Sudo A. Fibrin-related markers for diagnosing acute-, subclinical-, and pre-venous thromboembolism in patients with major orthopedic surgery. Int J Hematol. 2016;103:560-6.

49. Ito T, Fujimoto N, Taniguchi M, Ito M. Congenital extrahepatic portosystemic shunt with multiple visceral aneurysms. Intern Med. 2016;55:207.

50. Kakuta K, Dohi K, Sato Y, Yamanaka T, Kawamura M, Ogura T, Nakamori S, Fujimoto N, Fujii E, Yamada N, Ito M. Chronic inflammatory disease is an independent risk factor for coronary flow velocity reserve impairment unrelated to the processes of coronary artery calcium deposition. J Am Soc Echocardiogr. 2016;29:173-80.

51. Omori T, Nakamori S, Dohi K, Fujimoto N, Kumagai N, Fujii E, Ishida M, Ichikawa Y, Takahashi T, Yamada N, Sakuma H, Ito M. Persistent left ventricular apical ballooning induced by right ventricular apical pacing. Circ J. 2015;79:2723-5.

52. Izumi D, Miyahara M, Fujimoto N, Fukuoka S, Sakai M, Dohi K, Ito M. Optical coherence tomography analysis of the stent strut and prediction of resolved strut malapposition at 3 months after 2nd-generation drug-eluting stent implantation. Heart Vessels. 2016;31:1247-56.

53. Takeuchi T, Dohi K, Omori T, Moriwaki K, Sato Y, Nakamori S, Fujimoto N, Fujii E, Yamada N, Ito M. Diuretic effects of sodium-glucose cotransporter 2 inhibitor in patients with type 2 diabetes mellitus and heart failure. Int J Cardiol. 2015;201:1-3.

54. Masuda J, Tanigawa T, Yamada T, Nishimura Y, Sasou T, Nakata T, Sawai T, Fujimoto N, Dohi K, Miyahara M, Nishikawa M, Nakamura M, Ito M. Effect of combination therapy of ezetimibe and rosuvastatin on regression of coronary atherosclerosis in patients with coronary artery disease. Int Heart J. 2015;56:278-85.

55. Tanimura M, Dohi K, Matsuda M, Sato Y, Sugiura E, Kumagai N, Nakamori S, Yamada T, Fujimoto N, Tanigawa T, Yamada N, Nakamura M, Ito M. Renal resistive index as an indicator of the presence and severity of anemia and its future development in patients with hypertension. BMC Nephrol. 2015;16:45.

56. Takeuchi T, Dohi K, Kumagai N, Nakamori S, Fujimoto N, Okamoto R, Fujii E, Kitamura T, Yamada N, Nakamura M, Hamada M, Ito M. Effects of cardiac resynchronization therapy on left ventricular mechanical desynchrony induced by right ventricular pacing in a patient with heart failure and preserved ejection fraction. Int J Cardiol. 2014;177:1069-72.

57. Cornwell WK 3rd, Tarumi T, Aengevaeren VL, Ayers C, Divanji P, Fu Q, Palmer D, Drazner MH, Meyer DM, Bethea BT, Hastings JL, Fujimoto N, Shibata S, Zhang R, Markham DW, Levine BD. Effect of pulsatile and nonpulsatile flow on cerebral perfusion in patients with left ventricular assist devices. J Heart Lung Transplant. 2014;33:1295-303.

58. Best SA, Bivens TB, Palmer MD, Boyd KN, Galbreath MM, Okada Y, Carrick-Ranson GC, Fujimoto N, Shibata S, Hastings JL, Spencer MD, Tarumi T, Levine BD, Fu Q. Heart rate recovery after maximal exercise is blunted in hypertensive seniors. J Appl Physiol. 2014;117:1302-7.

59. Bhella PS, Hastings JL, Fujimoto N, Shibata S, Carrick-Ranson G, Palmer MD, Boyd KN, Adams-Huet B, Levine BD. Impact of lifelong exercise "dose" on left ventricular compliance and distensibility. J Am Coll Cardiol. 2014;64:1257-66.

60. Fujimoto N, Nakajima H, Sugiura E, Dohi K, Kanemitsu S, Yamada N, Aoki Y, Nakatani K, Shimpo H, Nobori T, Ito M. Bilateral giant coronary aneurysms in a 40-year-old male with Noonan syndrome caused by a KRAS germline mutation. Int J Cardiol. 2014;173:e63-6.

61. Carrick-Ranson G, Hastings JL, Bhella PS, Fujimoto N, Shibata S, Palmer MD, Boyd K, Livingston S, Dijk E, Levine BD. The effect of lifelong exercise dose on cardiovascular function during exercise. J Appl Physiol (1985). 2014;116:736-45.

62. Ito T, Ishikawa E, Fujimoto N, Okubo S, Ito G, Ichikawa T, Nomura S, Ito M. Effects of aliskiren on blood pressure and humoral factors in hypertensive hemodialysis patients previously on angiotensin II receptor antagonists. Clin Exp Hypertens. 2014;36:497-502.

63. Oosugi K, Fujimoto N, Dohi K, Machida H, Onishi K, Takeuchi M, Nomura S, Takeuchi H, Nobori T, Ito M. Hemodynamic and pathophysiological characteristics of intradialytic blood pressure elevation in patients with end-stage renal disease. Hypertens Res. 2014;37:158-65.

64. Fujimoto N, Hastings JL, Carrick-Ranson G, Shafer KM, Shibata S, Bhella PS, Abdullah SM, Barkley KW, Adams-Huet B, Boyd KN, Livingston SA, Palmer D, Levine D. Cardiovascular effects of 1 year of alagebrium and endurance exercise raining in healthy older individuals. Circ Heart Fail. 2013;6:1155-64.

65. Fujimoto N, Okada Y, Shibata S, Best SA, Bivens TB, Levine BD, Fu Q. Effects f sex and hypertension subtype on haemodynamics and left ventricular diastolic unction in older patients with stage 1 hypertension. J Hypertens. 2013;31:2282-9.

66. Sarma S, Carrick-Ranson G, Fujimoto N, Adams-Huet B, Bhella PS, Hastings JL, Shafer KM, Shibata S, Boyd K, Palmer D, Szczepaniak EW, Szczepaniak LS, Levine D. Effects of age and aerobic fitness on myocardial lipid content. Circ Cardiovasc Imaging. 2013;6:1048-55.

67. Markham DW, Fu Q, Palmer MD, Drazner MH, Meyer DM, Bethea BT, Hastings JL, Fujimoto N, Shibata S, Levine BD. Sympathetic neural and hemodynamic responses to upright tilt in patients with pulsatile and nonpulsatile left ventricular assist devices. Circ Heart Fail. 2013;6:293-9.

68. Fujimoto N, Prasad A, Hastings JL, Bhella PS, Shibata S, Palmer D, Levine BD. Cardiovascular effects of 1 year of progressive endurance exercise training in patients with heart failure with preserved ejection fraction. Am Heart J. 2012;164:869-77.

69. Fujimoto N, Borlaug BA, Lewis GD, Hastings JL, Shafer KM, Bhella PS, Carrick-Ranson G, Levine BD. Hemodynamic responses to rapid saline loading: the impact of age, sex, and heart failure. Circulation. 2013;127:55-62.

70. Carrick-Ranson G, Hastings JL, Bhella PS, Shibata S, Fujimoto N, Palmer D, Boyd K, Levine BD. The effect of age-related differences in body size and composition on cardiovascular determinants of VO2max. J Gerontol A Biol Sci Med Sci. 2013;68:608-16.

71. Carrick-Ranson G, Hastings JL, Bhella PS, Shibata S, Fujimoto N, Palmer MD, Boyd K, Levine BD. Effect of healthy aging on left ventricular relaxation and diastolic suction. Am J Physiol Heart Circ Physiol. 2012;303:H315-22.

72. Fujimoto N, Hastings JL, Bhella PS, Shibata S, Gandhi NK, Carrick-Ranson G, Palmer D, Levine BD. Effect of ageing on left ventricular compliance and distensibility in healthy sedentary humans. J Physiol. 2012;590:1871-80.

73. Fujimoto N, Shibata S, Hastings JL, Carrick-Ranson G, Bhella PS, Palmer D, Fu Q, Levine BD. Effects of pericardial constraint and ventricular interaction on left ventricular hemodynamics in the unloaded heart. Am J Physiol Heart Circ Physiol. 2011;300:H1688-95.

74. Fujimoto N, Prasad A, Hastings JL, Arbab-Zadeh A, Bhella PS, Shibata S, Palmer D, Levine BD. Cardiovascular effects of 1 year of progressive and vigorous exercise training in previously sedentary individuals older than 65 years of age. Circulation. 2010;122:1797-805.

75. Murata T, Dohi K, Onishi K, Sugiura E, Fujimoto N, Ichikawa K, Ishikawa E, Nakamura M, Nomura S, Takeuchi H, Nobori T, Ito M. Role of haemodialytic therapy on left ventricular mechanical dyssynchrony in patients with end-stage renal disease quantified by speckle-tracking strain imaging. Nephrol Dial Transplant. 2011;26:1655-61.

76. Fujimoto N, Onishi K, Sato A, Terasaki F, Tsukada B, Nozato T, Yamada T, Imanaka-Yoshida K, Yoshida T, Ito M, Hiroe M. Incremental prognostic values of serum tenascin-C levels with blood B-type natriuretic peptide testing at discharge in patients with dilated cardiomyopathy and decompensated heart failure. J Card Fail. 2009;15:898-905.

77. Kurita T, Onishi K, Dohi K, Takamura T, Fujimoto N, Tanigawa T, Imanaka-Yoshida K, Wada H, Nobori T, Ito M. Conventional therapy with an ACE inhibitor diminishes left ventricular dyssynchrony during the progression of heart failure. Int J Cardiol. 2010;140:48-54.

78. Omichi C, Fujimoto N, Kawasaki A, Kasai A. Ischemia-induced Brugada-type ST-segment alternans and Brugada syndrome. Int J Cardiol. 2010;144:429-30.

79. Fujimoto N, Onishi K, Dohi K, Tanabe M, Kurita T, Takamura T, Yamada N, Nobori T, Ito M. Hemodynamic characteristics of patients with diastolic heart failure and hypertension. Hypertens Res. 2008;31:1727-35.

80. Takamura T, Onishi K, Sugimoto T, Kurita T, Fujimoto N, Dohi K, Tanigawa T, Isaka N, Nobori T, Ito M. Patients with a hypertensive response to exercise have impaired left ventricular diastolic function. Hypertens Res. 2008;31:257-63.

81. Kurita T, Onishi K, Dohi K, Tanabe M, Fujimoto N, Tanigawa T, Setsuda M, Isaka N, Nobori T, Ito M. Impact of heart rate on mechanical dyssynchrony and left ventricular contractility in patients with heart failure and normal QRS duration. Eur J Heart Fail. 2007;9:637-43.

82. Yamanaka T, Onishi K, Tanabe M, Dohi K, Funabiki-Yamanaka K, Fujimoto N, Kurita T, Tanigawa T, Kitamura T, Ito M, Nobori T, Nakano T. Force- and relaxation-frequency relations in patients with diastolic heart failure. Am Heart J. 2006;152:966.e1-7.

83. Fujimoto N, Onishi K, Tanabe M, Dohi K, Funabiki K, Kurita T, Yamanaka T, Nakajima K, Ito M, Nobori T, Nakano T. Nitroglycerin improves left ventricular relaxation by changing systolic loading sequence in patients with excessive arterial load. J Cardiovasc Pharmacol. 2005;45:211-6.

84. Fujimoto N, Onishi K, Tanabe M, Koji T, Omichi C, Kato S, Kawasaki A, Nakano T, Ito M. Two cases of giant aneurysm in coronary-pulmonary artery fistula associated with atherosclerotic change. Int J Cardiol. 2004;97:577-8.

85. Fujimoto N, Masuoka H, Kosaka H, Ota S, Ito M, Nakano T. Primary amyloidosis with pulmonary involvement which presented exudative pleural effusion and high fever. Intern Med. 2003;42:756-60.

86. Matsuoka K, Okubo S, Fujii E, Uchida F, Kasai A, Aoki T, Makino K, Omichi C, Fujimoto N, Ohta S, Sawai T, Nakano T. Evaluation of the arrhythmogenecity of stress-induced "Takotsubo cardiomyopathy" from the time course of the 12-lead surface electrocardiogram. Am J Cardiol. 2003;92:230-3.