職名 寄附講座教授
氏名 まつだ ただし
松田 直
生年月 1962.09
所属 部局 医学系研究科
学科・専攻 生命医科学専攻
講座 寄附講座
教育研究分野 周産期新生児発達医学
TEL +81-59-232-1111 (内線6433)
FAX +81-59-231-5202
E-mail choku@yonaha.jp
個人のホームページ なし
学歴 北海道大学 (1981年04月01日~1987年03月31日) 卒業・修了
学位 1999.03 医学博士 北海道大学
所属学会 日本小児科学会,日本周産期新生児医学会,日本新生児成育医学会
社会活動 なし
職歴 S62. 神戸市立中央市民病院
H01.北海道大学 医学部附属病院 分娩部
H01.北海道社会保険中央病院 小児科
H02.市立札幌病院 新生児センター
H03.帯広厚生病院 小児科
H04.市立札幌病院 新生児センター
H06.北海道大学病院 周産母子センター
H15.東北大学病院 周産母子センター
H29.八戸市立市民病院 新生児集中治療室
H31.ヨナハ産婦人科小児科病院
R02.現職
学術(芸術)賞 なし
専門分野 胎児生理学,発達神経学,人工胎盤・人工子宮,新生児集中治療,新生児乳幼児の発達支援
現在の研究課題 胎生期における脳subplate層の障害が出生後の中枢神経系発達に与える影響の解析
担当科目 なし
主な業績等 1. Matsuda T, Nakajima T, Hattori S, Hanatani K, Fukazawa Y, Kobayashi K, Fujimoto S. Necrotizing funisitis: clinical significance and association with chronic lung disease in premature infants. Am J Obstet Gynecol 1997; 177: 1402-7.
2. Matsuda T, Okuyama K, Cho K, Hoshi N, Matsumoto Y, Kobayashi Y, Fujimoto S. Induction of antenatal periventricular leukomalacia by hemorrhagic hypotension in the chronically instrumented fetal sheep. Am J Obstet Gynecol 1999; 181(3): 725-30.
3. Cho K, Matsuda T, Okajima S, Matsumoto Y, Sagawa T, Fujimato S, Kobayashi K. Factors influencing pulmonary surfactant protein A levlels in cord blood, maternal blood and amniotic fluid. Biol Neonate 1999; 75(2):104-10.
4. Ohta H, Cho K, Matsumoto Y, Matsuda T, Ohyu J, Fujimoto S & Honma K. The observation of an ultradian rhythm of heart rate in low birth weight infants. Biol Rhythm Res 1999; 30: 545-54.
5. Cho K, Matsuda T, Okajima S, Matsumoto Y, Sagawa T, Fujimoto S, Kobayashi K. Prediction of respiratory distress syndrome by the level of pulmonary surfactant protein A in cord blood sera. Biol Neonate 2000; 77: 83-7.
6. Hoshi Y, Kohri S, Matsumoto Y, Cho K, Matsuda T, Okajima S, Fujimoto S. Hemodynamic responses to photic stimulation in neonates. Pediatr Neurol 2000; 23: 323-7.
7. Kobayashi Y, Yamada M, Omata Y, Koyama T, Matsuda T, Okuyama K, Fujimoto S, Furuoka H, Mataui T. Naturally-occurring Neospora caninum infection in an adult sheep and her twin fetuses. J Parasitol 2001; 87: 434-6.
8. Okajima S, Matsuda T, Cho K, Matsumoto Y, Kobayashi Y, Fujimoto S. Antenatal dexamethasone administration impairs normal postnatal lung growth in rats. Pediatr Res 2001; 49: 777-81.
9. Kiguchi S, Matsuda T, Cho K, Okuyama K, Akahane M, Fujimoto S. KUR-1246, a novel ß2-adrenoceptor agonist, as a tocolytic agent. Obstet Gynecol 2002; 100: 487-94.
10. Kusaka T, Matsuda T, Okuyama K, Cho K, Kishida K, Kobayashi Y, Fujimoto S. Analyses of factors contributing to vulnerability to antenatal periventricular leukomalacia induced by hemorrahagic hypotention in chronically instrumented fetal sheep. Pediatr Res 2002; 51: 20-4.
11. Murata S, Matsuda T, Kiguchi S, Kobayashi M, Cho K, Okuyama K. Effects of long-term administration of KUR-1246, a selective 2-adrenoceptor agonist, on pregnant sheep and their fetuses. BJOG 2005; 112: 69-74.
12. Matsuda T, Okuyama K, Cho K, Okajima S, Kobayashi Y, Hoshi Y, Kobayashi K. Cerebral hemodynamics during the induction of antenatal periventricular leukomalacia by hemorrhagic hypotension in chronically instrumented fetal sheep. Am J Obstet Gynecol 2006; 194: 1057-63.
13. Ueda K, Cho K, Matsuda T, Okajima S, Uchida M, Kobayashi Y, Minakami H, Kobayashi K. A rat model for arrest of alveolarization induced by antenatal endotoxin administration. Pediatr Res 2006; 59: 396-400.
14. Cho K, Nakata K, Ariga T, Okajima S, Matsuda T, Ueda K, Furuta I, Kobayashi K, Minakami H. Successful treatment of congenital pulmonary alveolar proteinosis with intravenous immunogloblin G administration. Respirology 2006; 11 Supple: S74-7.
15. Uematsu M, Sakamoto O, Nishio T, Ohura T, Matsuda T, Inagaki T, Abe T, Okamura K, Kondo Y, Tsuchiya S. A case surviving for over a year of renal tubular dysgenesis with compound heterozygous angiotensinogen gene mutations. Am J Med Genet A.2006; 140: 2355-60.
16. Wang F, Zou Y, Tanaka M, Matsuda T, Chonan S. Unconstrained cardiorespiratory monitor for premature infants. Int J Appl Electrom 2007: 25; 469-75.
17. Watanabe T, Matsuda T, Hanita T, Okuyama K, Cho K, Kobayashi K, Kobayashi Y. Induction of necrotizing funisitis by fetal administration of intravenous granulocyte-colony stimulating factor and intra-amniotic endotoxin in premature fetal sheep. Pediatr Res 2007; 62: 670-3.
18. Ohta H, Xu S, Moriya T, Iigo M, Watanabe T, Nakahata N, Chisaka H, Hanita T, Matsuda T, Ohura H, Kimura Y, Yaegashi N, Tei H, Okamura K. Maternal feeding controls fetal biologic clock. PLoS ONE 2008; 3: e2601-5.
19. Saito M, Matsuda T, Okuyama K, Kobayashi Y, Kitanishi R, Hanita T, Okamura K. Effect of intrauterine inflammation on fetal cerebral hemodynamics and white matter injury in chronically instrumented fetal sheep. Am J Obstet Gynecol 2009; 200: 663.e1-663.e11.
20. Hanita T, Miyazawa H, Ohta H, Matsuda T. Monitoring preterm infants' vision development with light – only melanopsin is functional. J Pediatr 2009; 155: 596-596.e1.
21. Akiyama S, Ohta H, Watanabe S, Moriya T, Hariu A, Nakahata N, Chisaka H, Matsuda T, Kimura Y, Tsuchiya S, Tei H, Okamura K, Yaegashi N. The uterus sustains stable biological clock during pregnancy. Tohoku J Exp Med 2010; 221: 287-98.
22. Miura Y, Matsuda T, Funakubo A, Watanabe S, Kitanishi R, Saito M, Hanita T. Novel modification of an artificial placenta: pumpless arteriovenous extracorporeal life support in a premature lamb model. Pediatr Res 2012; 72: 490-4.
23. Watanabe S, Akiyama S, Hanita T, Li H, Nakagawa M, Kaneshi Y, Ohta H; Japan RED filter study group (Matsuda T, et al). Designing Artificial Environments for Preterm Infants Based on Circadian Studies on Pregnant Uterus. Front Endocrinol 2013; 4: 113, 1-11.
24. Kaga M, Matsuda T, Watanabe T, Onodera S, Watanabe S, Usuda H, Ito S. Renal vasodilatory action of arginine vasopressin in extremely low birth weight infants. Tohoku J Exp Med 2013; 231: 159-64.
25. Kitanishi R, Matsuda T, Watanabe S, Saito M, Hanita T, Watanabe T, Kobayashi Y. Cerebral ischemia or intrauterine inflammation promotes differentiation of oligodendroglial precursors in preterm ovine fetuses: possible cellular basis for white matter injury. Tohoku J Exp Med 2014; 234: 299-307.
26. Miura Y, Saito M, Usuda H, Woodward E, Rittenschober-Böhm J, Kannan PS, Musk GC, Matsuda T, Newnham JP, Kemp MW. Ex-Vivo Uterine Environment (EVE) Therapy Induced Limited Fetal Inflammation in a Premature Lamb Model. PLoS One 2015; 10: e0140701.
27. Miura Y, Matsuda T, Usuda H, Watanabe S, Kitanishi R, Saito M, Hanita T, Kobayashi Y. A parallelized, pumpless artificial placenta system significantly prolonged survival time in a preterm lamb model. Artif Organs 2016: 40; E61-8.
28. Hanita T, Matsuda T, Saito M, Kitanishi R, Cho K, Harding R, Kobayashi Y. Potential role of prenatal inflammation in the impairment of lung development following mechanical ventilation of preterm lambs. Reprod Sci 2016: 24; 478-87. DOI: 10.1177/1933719116660846.
29. Itoh S, Matsuda T, Usuda H, Watanabe S, Kitanishi R, Hanita T, Watanabe T., Adachi O. Surgical Ligation for Patent Ductus Arteriosus in Extremely Premature Infants: Strategy to Reduce their Risk of Neurodevelopmental Impairment. Tohoku J Exp Med 2016: 240; 7-13.
30. Usuda H, Watanabe S, Miura Y, Saito M, Musk GC, Rittenschober-Böhm J, Ikeda H, Sato S, Hanita T, Matsuda T, Jobe AH, Newnham JP, Stock SJ, Kemp MW. Successful maintenance of key physiological parameters in preterm lambs treated with ex vivo uterine environment therapy for a period of 1 week. Am J Obstet Gynecol 2017. pii: S0002-9378 (17) 30675-0. doi: 10.1016/j.ajog.2017.05.046.
31. Ito S, Yokoyama U, Saito J, Sato S, Usuda H, Watanabe S, Kitanishi R, Miura Y, Saito M, Hanita T, Matsuda T, Ishikawa Y. Attenuation of ductus arteriosus intimal thickening in preterm sheep twins compared with singletons. J Physiol Sci 2017. doi: 10.1007/s12576-017-0565-5.
32. Miura Y, Usuda H, Watanabe S, Woodward E, Saito M, Musk GC, Kallapur SG, Sato S, Kitanishi R, Matsuda T, Newnham JP, Stock SJ, Kemp MW. Stable control of physiological parameters, but not infection, in preterm lambs maintained on ex vivo uterine environment therapy. Artif Organs 2017; 41: 959-68. doi: 10.1111/aor.12974.
33. Watanabe S, Matsuda T, Hanita T, Ikeda H, Koshinami S, Sato S, Usuda H, Saito M, Kemp MW, Kobayashi Y. Organ Blood Flow in Response to Infusion of Arginine Vasopressin in Premature Fetal Sheep. Pediatr Int 2020 Pediatr Int 2020; 62: 688-693.