職名 講師
氏名 ひらいとしのり
平井利典
生年月 1986.08
所属 部局 附属病院
学科・専攻 薬剤部
講座  
教育研究分野 臨床薬剤学
TEL  
FAX  
E-mail hirai-toshinori@med. (末尾に mie-u.ac.jp を補ってください)
個人のホームページ https://researchmap.jp/t.hirai
学歴 明治薬科大学 学士課程 (2005年04月01日~2009年03月31日) 卒業・修了
明治薬科大学 博士課程・博士後期課程 (2012年04月01日~2016年09月30日) 卒業・修了
学位 2016.09 博士(薬学) 明治薬科大学
所属学会 日本臨床薬理学会 日本医療薬学会 日本TDM学会 日本腎臓病薬物療法学会 日本薬学会 日本腎臓学会
社会活動  
職歴 2009.04~2017.05 東京女子医科大学病院 薬剤師
2017.06~2018.03 東京女子医科大学東医療センター 薬剤師
2018.04~2020.11 東京女子医科大学東医療センター 薬剤師 主任
2020.12~ 三重大学医学部附属病院 薬剤部 講師
学術(芸術)賞 第40回日本臨床薬理学会学術総会 優秀演題賞,血管新生阻害薬投与患者におけるRAS阻害薬の抗尿蛋白効果と降圧コントロールの関係,2019.12
令和3年度「IATDMCT学術大会」派遣賞,テイコプラニンによる腎毒性発生の危険因子に関するメタ解析,2021.05
臨床薬理研究振興財団賞「学術論文賞」,心不全と心房細動を有する患者におけるジゴキシンの血中濃度と臨床アウトカムの関係,2021.12
専門分野 臨床薬理学・薬物動態学・医療薬学
現在の研究課題 医薬品適正使用を志向した臨床薬理学的研究
担当科目 チュートリアル教育「腎臓・泌尿器」 看護病態学III 臨床実習前集中講義(薬剤学:薬物相互作用)
主な業績等 Modeling and Simulation for Estimating the Influence of Renal Dysfunction on the Hypouricemic Effect of Febuxostat in Hyperuricemic Patients Due to Overproduction or Underexcretion of Uric Acid. 2016 Biological and Pharmaceutical Bulletin 39 1013-21
A retrospective study on the risk factors for bleeding events in warfarin therapy, focusing on renal function. 2017 European journal of clinical pharmacology 73 1491-1497
Evaluation of a pharmacokinetic-pharmacodynamic model for hypouricaemic effects of febuxostat using datasets obtained from real-world patients. 2018 British journal of clinical pharmacology 84 2260-2269
Impact of relative dose intensity on bone marrow suppression induced by S-1: retrospective observational study. 2018 Journal of pharmaceutical health care and sciences 4 30-
Low body mass index is a risk factor for hyperkalaemia associated with angiotensin converting enzyme inhibitors and angiotensin II receptor blockers treatments. 2018 Journal of clinical pharmacy and therapeutics 43 829-835
Correction to: Risk factors for vancomycin nephrotoxicity and time course of renal function during vancomycin treatment. 2019 European journal of clinical pharmacology 75 867-
Renin-angiotensin system inhibitors for countering proteinuria induced by angiogenesis inhibitors: a retrospective observational analysis. 2019 Cancer chemotherapy and pharmacology 84 195-202
Risk factors for vancomycin nephrotoxicity and time course of renal function during vancomycin treatment. 2019 European journal of clinical pharmacology 75 859-866
Clinical Predictors of the Hypoglycemic Effect of Sodium-Glucose Co-transporter-2 Inhibitors in Hyperuricemic Patients: A Retrospective Descriptive Observational Study. 2020 Biological and Pharmaceutical Bulletin 43 782-787
Drug-induced thrombotic microangiopathy using the Japanese pharmacovigilance database. 2020 International journal of clinical pharmacology and therapeutics 58 543-549
Effects of overweight and underweight on the treatment outcomes of rheumatoid arthritis patients treated with biological drugs: A retrospective observational descriptive study. 2020 Journal of clinical pharmacy and therapeutics 45 666-673
Geriatric Patients Are at a High Risk of Hypokalemia Associated with Yokukansan Preparation: A Retrospective Cohort Study. 2020 Biological and Pharmaceutical Bulletin 43 1742-1748
Relationship between Recurrent Falls and Medication Use during Acute-Care Hospitalization: A Retrospective Descriptive Study. 2020 Biological and Pharmaceutical Bulletin 42 1192-1198
Serum Digoxin Concentrations and Outcomes in Patients with Heart Failure and Atrial Fibrillation: A Single-Center Observational Study 2020 Japanese Journal of Clinical Pharmacology and Therapeutics 51 57-64
A meta-analysis of observational studies on anticholinergic burdenand fracture risk: evaluation of conventional burden scales. 2021 Journal of Pharmceutical Health Care and Sciences 7 30-41
Acute Kidney Injury Impacts on Hypokalemia Associated with Yokukansan Preparation: A Retrospective Observational Study. 2021 Biological and Pharmaceutical Bulletin 44 118-124
Clinical predictors of nephrotoxicity associated with teicoplanin: meta-analysis and meta-regression 2021 Basic & Clinical Pharmacology & Toxicology
Drug-drug interaction between azathioprine and allopurinol in patients with chronic kidney disease: a case series study 2021 BPB Reports 4 170-174
Effect of high-dose sulfamethoxazole/trimethoprim and glucocorticoid use on hyperkalemic event: A retrospective observational study. 2021 Journal of Infection and Chemotherapy 27 1607-1613
Involvement of the effect of renal hypoperfusion medications on vancomycin trough concentration: a secondary analysis using a retrospective observational data 2021 Basic & Clinical Pharmacology & Toxicology 129 376-384
Safety profiles of new xanthine oxidase inhibitors: A post-marketing study. 2021 International journal of clinical pharmacology and therapeutics 59 372-377
三重県下のがん診療病院における若年がん患者の妊孕性温存に関する医師,薬剤師,看護師を対象とした意識調査:薬剤師の役割に関する考察 共著 2021 日本病院薬剤師会雑誌 57 1379-1385
External evaluation of a Bayesian warfarin dose optimization based on a kinetic-pharmacodynamic model 2022 Biological and Pharmaceutical Bulletin 45 136-142
Pharmacokinetics of tacrolimus following an overdose in a patient with extreme obesity and genotype CYP3A5*3/*3: a case report 2022 The Journal of Toxicological Sciences 47 71-75
Population pharmacokinetic analysis and dosage recommendations for digoxin in Japanese patients with atrial fibrillation and heart failure using real-world data 2022 BMC Pharmacology and Toxicology
Population pharmacokinetic model of amiodarone and N-desethylamiodarone focusing on glucocorticoid and inflammation 共著 2022 Biological and Pharmaceutical Bulletin 45 948-954
医師,薬剤師に対する女性がん患者への晩期合併症のフォローアップに関する実態調査 2022 日本病院薬剤師会雑誌 58 781-787
Clinical risk factors for severity and prognosis of antiresorptive agent-related osteonecrosis of the jaw 共著 2022.09 Journal of Bone and Mineral Metabolism
Drug-drug interaction between remdesivir and immunosuppressant agents in a kidney transplant recipient 共著 2022.10 International Journal of Clinical Pharmacology and Therapeutics 60 439-444
Evaluation of bleeding and anticoagulation markers by edoxaban and low-dose cyclosporine: A case series study 共著 2022.10 Biopharmaceutics & Drug Disposition 43 192-200
Dual inhibition of CYP3A4 by voriconazole and clarithromycin influences tacrolimus pharmacokinetics: A case series 2022.11 European Journal of Drug Metabolism and Pharmacokinetics 47 889-893
Population kinetic-pharmacodynamic analysis of serum potassium in patients receiving sulfamethoxazole/trimethoprim 共著 2022.11 Basic & Clinical Pharmacology & Toxicology 131 380-391
検査値と画像データから読み解く 薬効・副作用評価マニュアル 単著or編著 2022.08 医学書院